South Carolina Department of Health and Environmental Control Laboratory Flexible Funding Model Grant Submission

SC-DHEC PHL-ISO摘要 南卡罗来纳州公共卫生与环境控制部(SC-DHEC) 实验室(PHL)，作为国家公共卫生实验室，致力于改善 南卡罗来纳州人的生活质量通过保护和促进公众和 环境。PHL食品微生物学实验室保持了检测 食源性致病菌和食品质量指标生物40多年和2016年 获得国际标准化组织/国际电工委员会17025认证，并自那时以来一直获得认证。在此期间 合作协议，食品微生物实验室将保持国际标准化组织/国际电工委员会17025 通过遵守我们的认证机构提出的要求进行认证，并 通过维护质量管理体系，满足并符合以下所有要素 国际标准化组织/国际电工委员会17025标准通过执行内部审核、管理评审、熟练程度 测试和质量体系改进。通过与国家制造的合作伙伴关系 食品零售计划标准(MFRPS)计划和州动物食品零售产品 计划标准(AFRPS)计划食品微生物实验室将参加 加强监测，共分析500个人类食物和动物样本 食品。将通过收集加强对食物防御反应的准备 用于分析炭疽芽孢杆菌和鼠疫耶尔森菌的50个样本。整体的表现 对400个分离株进行基因组测序将有助于增长对 微生物生态和多样性。通过常规监测产生的数据的共享 活动将允许食品和药物管理局访问我们的数据以供执行 活动。这些数据将在国际标准化组织/国际电工委员会17025认证的实验室中产生 将简化分析审查，并使FDA能够迅速做出反应并执行法规 合规性。这些项目将作为加强和改进FDA 努力预防食源性疾病和最大限度地减少接触，以便在国家 综合实验室科学系统，并为伙伴实验室配备额外资源 以增加国家范围内的样品吞吐能力。

SC-DHEC PHL-ISO Summary The South Carolina Department of Health and Environmental Control (SC-DHEC), Public Health Laboratory (PHL), serves as the state public health laboratory working towards improving the quality of life for South Carolinians by protecting and promoting the health of the public and environment. The PHL Food Microbiology Laboratory has maintained the ability to test for foodborne pathogens and food quality indicator organisms for over 40 years and in 2016 achieved ISO/IEC 17025 accreditation and has remained accredited since that time. During this cooperative agreement, the Food Microbiology Laboratory will maintain ISO/IEC 17025 accreditation by remaining compliant with requirements set forth by our accrediting body and by maintaining a quality management system that addresses and conforms to all elements of ISO/IEC 17025 standards by performing internal audits, management reviews, proficiency testing, and quality system improvements. Through a partnership with the state Manufactured Food Retail Program Standards (MFRPS) programs, and the state Animal Food Retail Product Program Standards (AFRPS) program the Food Microbiology Laboratory will participate in the enhanced surveillance with a total of 500 samples being analyzed for human food and animal food products. Preparedness for food defense response will be enhanced through the collection of 50 samples for analysis for Bacillus anthracis and Yersinia pestis. The performance of whole genome sequencing on 400 isolates will contribute to growing knowledge and understanding of microbial ecology and diversity. The sharing of this data generated through routine surveillance activities will allow the Food and Drug Administration access to our data for enforcement activities. The fact that this data will be generated in an ISO/IEC 17025 accredited laboratory will streamline analytical review and allow the FDA to rapidly respond and enforce regulatory compliance. These projects will serve as a foundation to strengthen and improve the FDA’s efforts to prevent foodborne illness and minimize exposures in order to build upon a nationally integrated laboratory science system and equips partner laboratories with additional resources to increase sample throughput capacity within the state.