Technology-Based Prevention for Adolescent Substance Use, Sexual Assault, and Sexual Risk in Primary Care

项目摘要 这项以患者为导向的导师研究职业发展奖(K23)的首要目标是 为阿曼达·吉尔莫博士提供成为独立医生所需的培训和研究活动 调查员。她的研究计划将专注于开发、测试和传播创新的、 以技术为基础的预防侧重于青少年药物使用、性侵犯(SA)和性风险 初级保健环境中的行为(SRB)。物质使用、性侵犯和性危险行为是 在青少年中很常见。它们同时发生，相互关联，形成综合预防 关注这些危害健康的行为势在必行。儿科初级保健机构的预防性就诊是一种 由于其潜在的广泛性，因此是实施简短、综合预防的理想地点。这项建议 包括培训活动，以确保吉尔莫博士实现以下五个新的职业目标：1)获得 对青少年进行综合预防培训，使其成为专注于预防的预防研究人员 物质使用、SA和SRB；2)在初级学校接受实施基于预防的临床试验的培训 使用筛查、短暂干预和转诊治疗(SBIRT)模式的护理环境；3)增强 临床试验和纵向分析的统计培训；4)加强创新应用的培训 将技术作为提供预防方案的一种方式；5)增加手稿写作、赠款写作和 授予管理技能；以及6)加强对研究道德的理解。导师团队包括 以下研究领域的专家心理学家和儿科医生：青少年综合预防 危险行为和暴力预防(赛尔夫-布朗，丹尼尔森)，儿科使用SBIRT物质(利维)， 以技术为基础的青少年预防方案(Ruggiero)，社区儿科研究 实践研究网络(Wallis)，来自临床试验的纵向数据分析(Ramakrishnan)，简要 对阿片类药物滥用和性危险行为的干预(库珀)，以及对性少数群体的干预 (凯森)。吉尔摩博士将把在培训活动中获得的技能应用到一个专注于研究项目的项目中 关于针对青少年药物使用的循证预防方案的适应和整合， 将性侵犯和性危险行为纳入以片剂为基础的初级保健预防计划。这项研究 该项目包括适应/集成阶段的焦点小组和专家输入，以及两者的可用性测试 社区儿科诊所内的青少年和医生，以及社区内的可行性研究 儿科诊所。可行性研究将确定进行更大规模随机对照试验的可行性。 测试新整合和适应的预防计划的有效性。该药的初步疗效观察 将对预防计划进行审查，但确定可行性是首要目标。这个奖项将为博士做准备。 Gilmore的独立研究生涯专注于开发、测试和传播 预防的重点是初级保健青少年中的药物使用、性侵犯和性风险。

PROJECT ABSTRACT The overarching goal of this Mentored Patient-Oriented Research Career Development Award (K23) is to provide Dr. Amanda Gilmore with the training and research activities needed to become an independent investigator. Her program of research will focus on the development, testing, and dissemination of innovative, technology-based prevention focused on adolescent substance use, sexual assault (SA), and sexual risk behaviors (SRBs) in primary care settings. Substance use, sexual assault, and sexual risk behaviors are common among adolescents. They occur concurrently and are interrelated, making integrated prevention concerning these health risk behaviors imperative. Preventative visits in pediatric primary care settings are an ideal location to implement brief, integrated prevention due to their potential for wide reach. This proposal includes training activities to ensure that Dr. Gilmore achieves the following five new career goals: 1) Receive training in integrated prevention for adolescents to become a prevention researcher focused on preventing substance use, SA, and SRBs; 2) Receive training in implementing prevention-based clinical trials in primary care settings using screening, brief intervention, and referral to treatment (SBIRT) models; 3) Enhance statistical training in clinical trials and longitudinal analyses; 4) Enhance training in the use of innovative technologies as a mode of delivering prevention programs; 5) Increase manuscript writing, grant writing, and grant management skills; and 6) Enhance understanding of research ethics. The mentorship team includes expert psychologists and pediatricians in the following areas of research: integrated prevention of adolescent risk behavior and violence prevention (Self-Brown, Danielson), substance use SBIRT in pediatrics (Levy), technology-based prevention programs for adolescents (Ruggiero), research within community pediatric practice research networks (Wallis), longitudinal data analyses from clinical trials (Ramakrishnan), brief interventions for opioid misuse and sexual risk behaviors (Cooper), and interventions for sexual minorities (Kaysen). Dr. Gilmore will apply the skills acquired during the training activities to a research project focused on the adaptation and integration of evidence-based prevention programs targeting adolescent substance use, sexual assault, and sexual risk behaviors to a tablet-based prevention program for primary care. The research project includes focus groups and expert input in the adaptation/integration phase, usability tests with both adolescents and physicians within community pediatric clinics, and a feasibility study within community pediatric clinics. The feasibility study will establish feasibility of conducting a larger randomized controlled trial testing the efficacy of the newly integrated and adapted prevention program. Preliminary efficacy of the prevention program will be examined, but determining feasibility is the primary goal. This award will prepare Dr. Gilmore for an independent research career focused on the development, testing, and dissemination of prevention focused on substance use, sexual assault, and sexual risk among adolescents in primary care.