Spatial Genomics for in situ single cell expression analysis in the brain
Spatial Genomics for in situ single cell expression analysis in the brain
批准号:
10254447
负责人:
Kirsten Frieda
金额:
$99.45万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
已结题
起止时间:
2018-07-01 至 2022-08-31
关键词:
AddressAdoptedAttentionBRAIN initiativeBrainCellsComputer softwareConfocal MicroscopyCustomDataData SetDevelopmentFamiliarityFluorescent in Situ HybridizationFutureGene ExpressionGene Expression ProfilingGenesGenomicsHumanImageIn SituIndustryLaboratoriesLiquid substanceMarketingMessenger RNAMethodsMicroscopeModelingMolecularMusNatureNeurodegenerative DisordersNeurosciencesPatternPhaseProductionPublicationsRNAResearchResearch PersonnelRunningSafetySamplingSiteSliceSpecific qualifier valueStandardizationTechnologyTestingTissuesTrainingbasebrain cellbrain tissuecell typecommercializationexperienceexperimental studygene panelinstrumentinterestnovelpreservationprototypescreeningsingle-cell RNA sequencingtouchscreentranscriptometranscriptomicsuser-friendly
中文摘要
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英文摘要
SUMMARY
Spatial Genomics, Inc. is commercializing seqFISH technology that can visualize thousands of
genes at the mRNA level in single cells with spatial information preserved. Recent advances now
make it possible to achieve 10,000 gene multiplexing in single cells directly in tissues (Eng et al.,
Nature 2019). With this technology, novel cell types can be discovered in situ and spatial
organizations can be directly identified and visualized in brain tissue sections.
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依托单位:
海外基金