CIVICS)PROGRAM - SARS-CoV-2 STUDIES

CIVICS) 计划 - SARS-CoV-2 研究

• 批准号: 10269386
• 负责人: FLORIAN KRAMMER
• 金额: $ 734.26万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-10 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10269386
• 关键词: 2019-nCoV; Basic Science; Biological Assay; COVID-19; Clinical Research; Clinical Trials; Development; Evaluation; Immune response; Immunity; Immunologics; In Vitro; Infection; Reagent; Support Contracts; Vaccine Design; design; efficacy testing; immunogenicity; in vivo; innovation; programs; vaccine candidate; vaccine delivery

This contract supports the design and evaluation of innovative vaccine candidates and delivery platforms that aim to achieve durable, robust and broadly protective immunity. Activities may include immunologic analyses to inform vaccine design and identify surrogates/correlates of protection; in vitro and in vivo immunogenicity and efficacy testing; assay and reagent development; and clinical studies and trials. Additional studies are being conducted to evaluate the immune response to SARS-CoV-2 infection.

该合同支持设计和评估创新的候选疫苗和交付平台，旨在实现持久、强大和广泛的保护性免疫。活动可包括免疫分析，以便为疫苗设计提供信息并确定替代物/保护性相关因素；体外和体内免疫原性和效力测试；分析和试剂开发；以及临床研究和试验。目前正在进行其他研究，以评估对SARS-CoV-2感染的免疫反应。