Administrative Core

项目摘要/摘要 修订后的科布雷应用免疫学和病理过程中心的目标是 建立国家认可的高级研究和培训计划，以促进 初级教员研究向专业自主研究经费投入在研究交叉点之间 免疫反应功能障碍和疾病发病机制。也就是说，我们希望成长为应用型 免疫学作为一门基础科学、临床科学和医学的重要学科在校园中的地位和作用 能够参与并与校园内所有其他中心协同工作的翻译科学。具体来说，我们 希望通过对免疫反应异常与疾病发病机制的认识，使我们 更好地了解免疫反应、免疫病理或疾病是如何改变的 发展随之而来。这一重点研究领域与我们目前的专业知识和我们新的 有针对性的初级教师招聘计划(2019年招聘了3名新的终身教职跟踪教师，直接符合 科布雷申请；2020年将有更多职位空缺)。为了实现这一目标，一个多方面的 研究计划的发展，以及指导和培训是必需的。政府当局 核心A将实施和管理所有Cobre计划计划，包括建立高级研究 核心设施，为初级教师发展建立导师计划，初级教师发展 讲习班，建立外部和内部咨询委员会以及一名高级导师 委员会，与外部研究专家协调，建立年度科学讨论会 和正式的评估程序，并建立支持发展的试点赠款机制 来自初级教员的有希望的项目。行政核心(核心A)将由Cobre Pi管理 以及协调员协助、核心管理协助和业务管理监督 计划预算。该核心将集中所有符合规定的Cobre计划文档和报告 符合NIH Cobre的要求。

PROJECT SUMMARY/ABSTRACT The goal of the revised COBRE Center for Applied Immunology and Pathological Processes is to establish a nationally recognized advanced research and training program that facilitates the development of junior faculty research toward major independent research funding in the research intersections between the dysfunctioning of the immune response and disease pathogenesis. That is, we hope to grow Applied Immunology as a discipline on campus because of its importance as a basic science, clinical science and a translational science that can engage and synergize with all of the other centers on campus. Specifically, we hope to focus on the understanding of abnormal immune responses with disease pathogenesis, such that we provide a better understanding of how when the immune response is altered, immunopathology or disease development ensues. This focused research area is in line with our current expertise and with our new targeted junior faculty hiring plan (3 new tenure track faculty have been hired in 2019 that fit directly with the COBRE application; additional positions will open in 2020). In order to accomplish this goal, a multifaceted plan for research program development along with mentorship and training is required. The Administration Core A will implement and manage all COBRE program initiatives including establishing advanced research core facilities, establishing a mentorship program for junior faculty development, junior faculty development workshops, establishing External and Internal Advisory Committees along with a Senior Mentoring Committee, coordination with the External Research Specialists, establishing an annual scientific colloquium and formal evaluation procedures, and establishing pilot grant mechanism that supports development of promising projects from junior faculty. The Administration Core (Core A) will be managed by the COBRE PI along with coordinator assistance, core management assistance, and business management oversight of the program budget. This core will centralize all COBRE program documentation and reporting in compliance with NIH COBRE requirements.