Novel approaches to control mast cell function in allergic inflammation.
Novel approaches to control mast cell function in allergic inflammation.
批准号:
nhmrc : 1127290
负责人:
A/Pr Michele Grimbaldeston
金额:
$49.38万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 2019-12-31
中文摘要
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英文摘要
Allergic disorders are a major health problem. Driven by mast cells, the underlying inflammation is exacerbated by the ‘?c family’ of cytokines acting on the surface of these cells. We aim to characterise the ‘mast cell-?c axis’ with the view to developing new therapies based on our ?c receptors blocking antibodies. This path of discovery-mechanism-translation seeks to recapitulate our previous success of taking a related antibody to Phase II clinical trials to treat patients with leukaemia.
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Novel approaches to control mast cell function in allergic inflammation.
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批准号:nhmrc : GNT1127290
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项目类别:Project Grants
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资助金额:$72.34万
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财政年份:2017
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Structure and Function of Human Fc Receptors
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批准号:nhmrc : GNT1079946
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项目类别:Project Grants
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资助金额:$67.35万
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财政年份:2015
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Structure and Function of Human Fc Receptors
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批准号:nhmrc : 1079946
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项目类别:Project Grants
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资助金额:$46.38万
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财政年份:2015
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Regulatory roles of mast cells in cutaneous dermatitis in vivo
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批准号:nhmrc : 1011203
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项目类别:Project Grants
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资助金额:$39.14万
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财政年份:2011
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Mast cell proteases suppress respiratory viral infections and alleric inflammation of the airways
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批准号:nhmrc : 1004185
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项目类别:NHMRC Project Grants
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资助金额:$44.38万
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财政年份:2011
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Mast cells as regulators of UVB-induced skin pathology and inflammation
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批准号:nhmrc : 626907
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项目类别:Career Development Fellowships
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资助金额:$26.3万
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财政年份:2010
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
The role of dermal mast cells in limiting the pathology associated with chronic low-dose UVB irradiation of the skin.
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批准号:nhmrc : 539800
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项目类别:NHMRC Project Grants
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资助金额:$34.27万
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财政年份:2009
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Regulation of cutaneous gene expression by mast cells
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批准号:nhmrc : 229968
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项目类别:Early Career Fellowships
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资助金额:$28.75万
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财政年份:2003
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
国内基金
海外基金
Lagrangian origin of geometric approaches to scattering amplitudes
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批准号:24ZR1450600
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项目类别:省市级项目
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资助金额:--
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批准年份:2024
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负责人:ALEXANDER OCHIROV
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依托单位: