The role of dermal mast cells in limiting the pathology associated with chronic low-dose UVB irradiation of the skin.

真皮肥大细胞在限制与皮肤慢性低剂量 UVB 照射相关的病理学中的作用。

• 批准号: nhmrc : 539800
• 负责人: A/Pr Michele Grimbaldeston
• 金额: $ 34.27万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-dermal-mast-irradiation-skin/81681
• 关键词: role; dermal; mast; cells; limiting

Australians are subject to high levels of sun exposure , that consequently can lead to skin damage and skin cancer. The specific aims of our reseearch are to investigate the role of skin mast cells in the limitation of skin alterations associated with chronic low-dose ultraviolet B exposure. Understanding the innate mechanisms that protect against excessive skin damage and cancer might aid the development of better treatment modalities in the future.

澳大利亚人受到高水平的阳光照射，因此可能导致皮肤损伤和皮肤癌。本研究的具体目的是探讨皮肤肥大细胞在慢性低剂量紫外线B暴露相关皮肤改变的限制中的作用。了解防止过度皮肤损伤和癌症的先天机制可能有助于未来开发更好的治疗方式。