Regulatory roles of mast cells in cutaneous dermatitis in vivo

肥大细胞在体内皮肤皮炎中的调节作用

• 批准号: nhmrc : 1011203
• 负责人: A/Pr Michele Grimbaldeston
• 金额: $ 39.14万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/regulatory-roles-mast-dermatitis-vivo/109562
• 关键词: Regulatory; roles; mast; cells; cutaneous

Allergic conditions that can affect the skin, such as contact dermatitis or eczema are common amongst Australians. Although not life threatening, these common skin conditions can cause considerable physical diability and be expensive to treat. The major focus of our research is to define how dermal mast cells can be modulated to help limit the tissue changes and damage associated with these skin conditions, and ultimately develop improved treatments in the future.

可能影响皮肤的过敏性疾病，如接触性皮炎或湿疹在澳大利亚人中很常见。虽然不危及生命，这些常见的皮肤病可能会导致相当大的身体disability和昂贵的treat.The我们的研究的主要重点是确定如何真皮肥大细胞可以被调制，以帮助限制与这些皮肤病相关的组织变化和损伤，并最终开发出改进的治疗方法在未来。