Structure and Function of Human Fc Receptors
Structure and Function of Human Fc Receptors
批准号:
nhmrc : GNT1079946
负责人:
A/Pr Michele Grimbaldeston
金额:
$67.35万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 --
中文摘要
我们已经发现了一种名为IgG4的罕见人类抗体是如何对人体免疫系统发挥重要的调节作用的。我们已经发现IgG4是如何“关闭”炎症性白细胞的,这对开发新的治疗方法具有广泛的意义,这些疗法可以关闭过敏和自身免疫性疾病,也可以打开对感染和癌症的免疫力。
英文摘要
We have discovered how a rare type of human antibody called IgG4 exerts a major regulatory influence on the body's immune system. We have discovered how IgG4 can 'switch' off inflammatory white blood cells which has broad implications for the development of new forms of therapy for switching off allergies and autoimmune diseases and for switching on immunity to infections and cancers.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Novel approaches to control mast cell function in allergic inflammation.
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批准号:nhmrc : GNT1127290
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项目类别:Project Grants
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资助金额:$72.34万
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财政年份:2017
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Novel approaches to control mast cell function in allergic inflammation.
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批准号:nhmrc : 1127290
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项目类别:Project Grants
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资助金额:$49.38万
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财政年份:2017
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Structure and Function of Human Fc Receptors
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批准号:nhmrc : 1079946
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项目类别:Project Grants
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资助金额:$46.38万
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财政年份:2015
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Regulatory roles of mast cells in cutaneous dermatitis in vivo
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批准号:nhmrc : 1011203
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项目类别:Project Grants
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资助金额:$39.14万
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财政年份:2011
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Mast cell proteases suppress respiratory viral infections and alleric inflammation of the airways
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批准号:nhmrc : 1004185
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项目类别:NHMRC Project Grants
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资助金额:$44.38万
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财政年份:2011
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Mast cells as regulators of UVB-induced skin pathology and inflammation
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批准号:nhmrc : 626907
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项目类别:Career Development Fellowships
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资助金额:$26.3万
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财政年份:2010
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
The role of dermal mast cells in limiting the pathology associated with chronic low-dose UVB irradiation of the skin.
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批准号:nhmrc : 539800
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项目类别:NHMRC Project Grants
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资助金额:$34.27万
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财政年份:2009
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
Regulation of cutaneous gene expression by mast cells
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批准号:nhmrc : 229968
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项目类别:Early Career Fellowships
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资助金额:$28.75万
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财政年份:2003
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负责人:A/Pr Michele Grimbaldeston
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依托单位:
国内基金
海外基金
原生动物四膜虫生殖小核(germline nucleus)体功能(somatic function)的分子基础研究
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批准号:31872221
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项目类别:面上项目
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资助金额:60.0万元
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批准年份:2018
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负责人:熊杰
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依托单位: