Yale Transdisciplinary Collaborative Center for Health Disparities Research (YALE-TCC)

耶鲁大学健康差异研究跨学科合作中心 (YALE-TCC)

• 批准号: 10272527
• 负责人: Oswald Peter Adams
• 金额: $ 123.49万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-16 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10272527
• 关键词: Address; Adult; African; Age-Years; Barbados; Behavioral; Biological; Caribbean region; Chronic Disease; Cohort Studies; Collaborations; Communication; Communities; Community Networks; Data; Data Analyses; Data Collection; Development; Diffusion; Early Diagnosis; Endowment; Enrollment; Ethics; Evaluation; Event; Evidence based intervention; Funding; Goals; Governing Board; Government Agencies; Grant; Health; Hispanics; Hypertension; Individual; Institution; Intervention; Knowledge; Lead; Methodology; Mission; Monitor; Network Infrastructure; New York; Non-Insulin-Dependent Diabetes Mellitus; Outcomes Research; Pilot Projects; Policies; Population; Primary Prevention; Process; Public Health; Puerto Rico; Research; Research Design; Research Infrastructure; Research Personnel; Resources; Risk; Risk Factors; Role; Series; Site; System; Testing; Time; Tobago; Trinidad; United States Virgin Islands; Work; base; biomedical informatics; care delivery; clinical care; clinical practice; clinically significant; contextual factors; cost effective intervention; data integration; data sharing; data warehouse; design; disorder risk; educational atmosphere; evidence base; health care delivery; health disparity; health equity promotion; high risk; hypertension prevention; improved; individual patient; innovation; medical schools; meetings; member; novel; precision medicine; programs; protective factors; public health relevance; tool; uptake; working group

 DESCRIPTION (provided by applicant): The Yale Transdisciplinary Collaborative Center for Health Disparities Research Focused on Precision Medicine (YALE-TCC) is a Region II coalition of research institutions (n=5), stakeholder member organizations (n > 80 individuals representing >30 organizations) focused on African descent and Hispanic populations living in the U.S. Virgin Islands and Puerto Rico. The YALE-TCC proposes a research portfolio that combines different types of data to improve our ability to identify who is at risk for hypertension (HTN) and type 2 diabetes (T2D) sooner than we can now. The YALE- TCC also supports pilot and demonstration projects. Through the coordinated activities of the YALE-TCC, the ultimate goal is to identify and test culturally relevant and low resource interventions to reduce the population burden of HTN and T2D and to inform clinical care delivery to individual patients at high risk for these diseases and their consequences.

 描述（由申请人提供）：耶鲁大学跨学科合作中心的健康差异研究专注于精准医学（YALE-TCC）是一个区域II联盟的研究机构（n=5），利益相关者成员组织（n > 80个人代表>30个组织）专注于生活在美属维尔京群岛和波多黎各的非洲裔和西班牙裔人口。YALE-TCC提出了一个结合不同类型数据的研究组合，以提高我们识别高血压风险人群的能力 (HTN)和2型糖尿病（T2 D）的发病率。耶鲁大学技术合作学院还支持试点和示范项目.通过YALE-TCC的协调活动，最终目标是确定和测试与文化相关的低资源干预措施，以减少HTN和T2 D的人口负担，并为这些疾病及其后果的高风险个体患者提供临床护理。

项目成果

Risk factors for household food insecurity in the Eastern Caribbean Health Outcomes Research Network cohort study.

• DOI: 10.3389/fpubh.2023.1269857
• 发表时间: 2023
• 期刊: FRONTIERS IN PUBLIC HEALTH
• 影响因子: 5.2
• 作者: Martinez-Brockman, Josefa L.;Hromi-Fiedler, Amber;Galusha, Deron;Oladele, Carol;Acosta, Lisbette;Adams, O. Peter;Maharaj, Rohan G.;Nazario, Cruz M.;Nunez, Maxine;Nunez-Smith, Marcella;Perez-Escamilla, Rafael
• 通讯作者: Perez-Escamilla, Rafael

Egocentric Health Networks and Cardiovascular Risk Factors in the ECHORN Cohort Study.

ECHORN 队列研究中的以自我为中心的健康网络和心血管危险因素。

• DOI: 10.1007/s11606-019-05550-1
• 发表时间: 2020
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: Oladele,CarolR;Thompson,Terri-Ann;Wang,Karen;Galusha,Deron;Tran,Emma;Martinez-Brockman,JosefaL;Adams,OswaldP;Maharaj,RohanG;Nazario,CruzM;Nunez,Maxine;Nunez-Smith,Marcella
• 通讯作者: Nunez-Smith,Marcella

Is hypertension in African-descent populations contributed to by an imbalance in the activities of the ACE2/Ang-(1-7)/Mas and the ACE/Ang II/AT1 axes?

• DOI: 10.1177/1470320320908186
• 发表时间: 2020-01-01
• 期刊: JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
• 影响因子: 2.9
• 作者: Cohall, Damian;Ojeh, Nkemcho;Nunez-Smith, Marcella
• 通讯作者: Nunez-Smith, Marcella

Consumption of sugar-sweetened beverages and T2D diabetes in the Eastern Caribbean.

• DOI: 10.1017/s1368980023000381
• 发表时间: 2023-07
• 期刊: PUBLIC HEALTH NUTRITION
• 影响因子: 3.2
• 作者: Oladele, Carol R.;Khandpur, Neha;Galusha, Deron;Hassan, Saria;Colon-Ramos, Uriyoan;Miller, Mary;Adams, Oswald P.;Maharaj, Rohan G.;Nazario, Cruz M.;Nunez, Maxine;Perez-Escamilla, Rafael;Hassell, Trevor;Nunez-Smith, Marcella
• 通讯作者: Nunez-Smith, Marcella

The relationship between non-permanent migration and non-communicable chronic disease outcomes for cancer, heart disease and diabetes - a systematic review.

非永久移民与癌症、心脏病和糖尿病等非传染性慢性疾病结果之间的关系——系统评价。

• DOI: 10.1186/s12889-019-6646-z
• 发表时间: 2019
• 期刊: BMC public health
• 影响因子: 4.5
• 作者: Wang,KarenH;Hendrickson,ZoéM;Brandt,CynthiaA;Nunez-Smith,Marcella
• 通讯作者: Nunez-Smith,Marcella