UniProt building community metrics for FAIR and TRUSTworthy resources

项目摘要 UNIPROT建立公平和值得信赖的资源的社区指标- 2022年申请 通用蛋白质资源（UniProt）的使命是支持生物医学研究， 提供了一个免费的、稳定的、全面的、丰富的和准确的注释序列， 知识库UniProt父母补助金补充申请的总体目标 （U24 HG 007822）是（i）支持UniProt评估并增加与FAIR和TRUST的一致性 原则，（ii）提供一种工具，使数据资源能够帮助评估其使用情况，效用， 影响，以及（iii）推进对跨数据储存库的数据重用的评估。UniProt已经 自2002年成立以来，一直是提供蛋白质序列和注释数据的领导者。作为 作为生物医学研究基础设施的一个重要组成部分， 专业化和强化其流程和发展。这也发生在 通过创建一系列原则，如公平原则和信任原则， 以及越来越多的各种认证。UniProt被认为是最初的范例 出版物描述公平的原则，也是一个早期采用的信任原则 于2020年5月获得CoreTrustSeal认证。我们将进一步自我评估我们的 公平和信任合规作为项目的一部分，导致一组目标，支持我们的 于2023年申请更新CoreTrustSeal认证。这项工作将有助于确保我们 与数据和元数据的社区标准保持一致，并更新我们的展望 UniProt的管理流程。我们相信，我们正处于发展的最前沿。 生物医学资源，并制定了一系列指标，以了解使用，影响， 和UniProt的效用。我们将在GoogleColab中开发一个界面，使社区能够查看 UniProt或任何其他感兴趣的生物医学资源的快速度量， 可用于文献和专利数据库的API。我们意识到UniProt数据被广泛重复使用 跨其他数据资源，这种重用非常难以衡量， 我们对生物医学数据资源的影响的理解存在最大的差距。我们将召开 与主要利益相关者讨论如何衡量NIH数据资源的重用。

PROJECT SUMMARY UNIPROT BUILDING COMMUNITY METRICS FOR FAIR AND TRUSTWORTHY RESOURCES- SUPPLEMENT REQUEST 2022 The mission of the Universal Protein Resource(UniProt) is to support biomedical research by providing a freely available, stable, comprehensive, richly and accurately annotated sequence knowledgebase. The overall goal of this Supplement application for the UniProt parent grant (U24HG007822) is to (i) support UniProt to assess and increase alignment with FAIR and TRUST principles, (ii) to provide a tool to enable data resources to help evaluate their usage, utility, and impact and (iii) advance the the evaluation of data reuse across data repositories. UniProt has been a leader in the provision of protein sequence and annotation data since its inception in 2002. As a large and central piece of the biomedical research infrastructure it has seen a progresive professionalisation and hardening of its processes and development. This has also happened to the field as a whole with the creation of sets of principles such as the FAIR and TRUST principles as well as a growing variety of certifications. UniProt was identified as an exemplar in the original publication describing the FAIR principles and was also an early adopter of the TRUST principles gaining CoreTrustSeal certification in May 2020. We will carry out a further self assessment of our FAIR and TRUST compliance as part of the project leading to a set of goals supporting our application for renewal of CoreTrustSeal certification in 2023. This work will help to ensure we remain well aligned with community standards for data and metadata as well as refresh our outlook for management processes of UniProt. We believe that we are at the forefront of developing biomedical resources and have developed a range of metrics for understanding the usage, impact and utility of UniProt. We will develop an interface in GoogleColab to enable the community to view metrics for UniProt or any other biomedical resource of interest in a rapid way based on publicly available APIs to literature and patent databases. We are aware that UniProt data is widely reused across other data resources and this reuse is extremely difficult to measure and can be considered the greatest gap in our understanding of the impact of biomedical data resources. We will hold a workshop with key stakeholders to discuss ways to measure reuse across NIH data resources.