Integrated Health Sciences Facility Core

综合健康科学设施核心

• 批准号: 10600012
• 负责人: Fred A. Wright
• 金额: $ 27.03万
• 依托单位: NORTH CAROLINA STATE UNIVERSITY RALEIGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-20 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10600012
• 关键词: Affect; Basic Science; Bioinformatics; Biological Models; Clinical; Clinical Research; Communication; Communities; Core Facility; Data; Data Science; Data Scientist; Dedications; Discipline; Ensure; Environment; Environmental Exposure; Environmental Health; Environmental Impact; Epidemiologist; Epidemiology; Funding; Goals; Health; Health Sciences; Human; Human Resources; Institution; Integrative Medicine; Interdisciplinary Study; International; Libraries; Link; Mission; Modeling; Population; Population Study; Prevention; Public Health; Research; Research Personnel; Resources; Sampling; Scientist; Specialist; Structure; System; Tissues; Translating; Translational Research; Translations; community engagement; community organizations; data curation; data integration; data management; data science resource; data streams; data visualization; experimental study; health data; health science research; human study; improved; knowledgebase; member; method development; public health priorities; success

ABSTRACT-INTEGRATIVE HEALTH SCIENCES FACILITY CORE: The Integrative Health Sciences Facility Core (IHSFC) of the Center for Human Health and the Environment (CHHE) is the central interface between basic scientists, data scientists, epidemiologists, clinical researchers, and public health practitioners. Its mission is to catalyze multidirectional translation of research between diverse model systems, population-based studies, and community partners to advance understanding about the effects of environmental exposures on human health and facilitate use of this information by affected communities to improve public health. The intentional disciplinary diversity of the IHSFC leaders has developed the Core into a highly effective resource for CHHE’s internationally renowned scientists who leverage diverse models for environmental health science (EHS) research, bioinformaticists who integrate data streams from across the health sciences, and epidemiologists and community engagement specialists who are substantively involved in local communities and translating CHHE research to improve public health. The IHSFC has been highly successful in its goal to establish key translational partnerships and resources and facilitate new and impactful interdisciplinary research connections and community engagement initiatives. Reflection on these successes revealed that a major factor in these connections was access to data science resources for interpreting, linking, and communicating results from basic science experiments through human studies and, ultimately, community engagement. Therefore, in the next funding cycle the previously separate data science efforts have been expanded and integrated into a new IHSFC Environmental Data Science Group (EDSG) that provides Center members clear access to significant data science capabilities. With expertise drawn from the Bioinformatics Research Center and the NC State Libraries, the EDSG component of IHSFC provides best-practices in data management, analysis, and sharing into all Center activities. Additionally, in the next funding cycle the IHSFC will revise its key personnel to accommodate the addition of the EDSG, will establish and extend key programmatic partnerships, and is creating new and enhancing existing resources at NC State and partner institutions. These activities will promote new opportunities for multidirectional translation between basic science, clinical research, and community organizations.

摘要-综合健康科学因素核心： 人类健康与环境中心的综合健康科学设施核心（IHSFC） （CHHE）是基础科学家，数据科学家，流行病学家，临床研究人员， 和公共卫生从业人员。它的使命是促进研究之间的多方向翻译 不同的模型系统，基于人口的研究，以及社区合作伙伴，以促进对 环境接触对人类健康的影响，并促进受影响者使用这一信息 社区改善公共卫生。IHSFC领导人有意的学科多样性 将核心开发成CHHE国际知名科学家的高效资源， 利用环境健康科学（EHS）研究的各种模型，整合数据的生物信息学家 来自健康科学界的专家，流行病学家和社区参与专家， 实质性地参与当地社区，并将CHHE研究转化为改善公共卫生。的 IHSFC在建立关键的翻译伙伴关系和资源的目标方面非常成功， 促进新的和有影响力的跨学科研究联系和社区参与倡议。 对这些成功的反思表明，这些联系的一个主要因素是获得数据科学 资源解释，链接，并通过人类交流基础科学实验的结果 研究，最终，社区参与。因此，在下一个供资周期， 数据科学工作已经扩大，并整合到一个新的IHSFC环境数据科学组 （EDSG），为中心成员提供了明确的访问重要的数据科学能力。具有专门知识的 来自生物信息学研究中心和NC州立图书馆，IHSFC的EDSG组件 为中心的所有活动提供数据管理、分析和共享方面的最佳实践。此外，在 下一个资助周期，IHSFC将调整其关键人员，以适应EDSG的增加， 建立和扩大关键的方案伙伴关系，并正在创造新的和加强现有的资源， 北卡罗来纳州和伙伴机构。这些活动将促进多向翻译的新机会 在基础科学、临床研究和社区组织之间。