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整体项目总结 INBRE续展申请的总体目标是促进高质量的生物医学研究活动 在路易斯安那州全州,重点是建设研究能力和劳动力发展。 从2016年开始,对整体业务进行了重新组织,以最大限度地提高效力和影响。简单地说, 这些措施包括:1)指导委员会成员通过每两年举行一次务虚会和 各主要本科院校(PUI)提供书面报告。2)任命核心联络员 每个PPI的主任(CLO)直接评估个别项目和教师的需求,并将其转介给LBRN 生物信息学、生物统计学和计算生物学核心(BBCC)和分子细胞生物学 资源核心(MCBRC)。3)建立“核心雄鹿”筹资机制,以支持获取核心 对于所有的PUI教职员工。在本申请中,提出了更多的主要更改,以进一步改善目前的 成功的LBRN计划:1)将PUI的数量从7个扩大到8个,增加了 新奥尔良(UNO)校区。2)我们将把本科生的研究经验扩大到包括 一学年,以及在学术和工业环境中的暑期经历。重要的是, 路易斯安那州董事会(劳工)已经认识到LBRN在全州生物医学中的主要影响 研究和培训,并将提供比赛资金约为。在五年内为LBRN提供120万美元 暑期研究项目。路易斯安那州立大学也提供了重要支持,包括路易斯安那州立大学兽医学院 医学(支持向量机)和计算与技术中心(CCT)。3)我们首次启动了一项 为LBRN计划争取非营利机构以及 来自营利性机构。我们预计这一努力将为本科生提供额外的暑期津贴。 学生以及新的托管机构,并为扩大生物医学劳动力做出贡献 路易斯安那州。本申请的主要目标将通过以下具体目标来实现: 具体目标一:维护和扩大以前建立的全州基础设施和 支持跨学科生物医学研究的智力研究网络。 具体目标二:扩大和提高PUI校区生物医学研究人员的临界人数 通过有指导的研究和加强沟通的支持。 具体目标三:提高本科生在整个生物医学研究职业生涯中的兴趣 路易斯安那州通过提供暑期和学年研究机会给所有PUI机构 州政府。 具体目标四:通过以下方式评价、评估和持续监测LBRN内的进展 详细跟踪研究成果、人力资源开发和生产情况 参与机构之间的合作。
英文摘要
OVERALL Project Summary The overall goal of this INBRE renewal application is the facilitation of quality biomedical research activities throughout the State of Louisiana with an emphasis on building research capacity and workforce development. Starting with 2016, overall operations have been re-organized to maximize effectiveness and impact. Briefly, these include: 1) Direct engagement of the Steering Committee members by having bi-annual retreats and written reports provided by each Primarily Undergraduate Institution (PUI). 2) The appointment of Core Liaison Officers (CLO) in each PUI to directly evaluate individual projects and faculty needs and referral to the LBRN Cores, Bioinformatics Biostatistics and Computational Biology Core (BBCC) and Molecular Cell Biology Resources Core (MCBRC). 3) The creation of a “Core Bucks” funding mechanism to support access to cores for all PUI faculty. In this application, additional major changes are proposed to further improve the currently successful LBRN program: 1) Expansion of the number of PUIs from seven to eight by adding the University of New Orleans (UNO) campus. 2) We will expand undergraduate research experiences to include entire academic year, as well as summer experiences in both academic and industrial settings. Importantly, the Louisiana Board of Regents (LABoR) has recognized the major impact of LBRN in state-wide biomedical research and training and will provide match funding of approx. $1.2 million over five years for the LBRN summer research program. Significant support is also provided by LSU including the LSU School of Veterinary Medicine (SVM) and the Center for Computation & Technology (CCT). 3) For the first time, we have initiated a campaign to solicit additional financial support for the LBRN program from not-for-profit-institutions, as well as from for-profit institutions. We expect that this effort will provide additional summer stipends for undergraduate students, as well as new hosting institutions and contribute to the expansion of biomedical workforce in Louisiana. The major objectives of this application will be accomplished through the following specific aims: Specific Aim I: Maintain and expand the previously established state-wide infrastructure and intellectual research network supporting interdisciplinary biomedical research. Specific Aim II: Expand and improve the critical mass of biomedical investigators at PUI campuses through the support of mentored research and enhanced communication. Specific Aim III: Increase undergraduate student interest in biomedical research careers throughout Louisiana by providing summer and academic year research opportunities to all PUI institutions within the state. Specific Aim IV: Evaluate, assess, and continuously monitor the progress within LBRN through detailed tracking of research accomplishments, the development of human resources, and productive collaborations among participating institutions.
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DOI: 10.1177/17590914221101704
发表时间: 2022-01
期刊: ASN NEURO
影响因子: 4.7
作者: [Nwokwu, Chukwumaobim Daniel, Xiao, Adam Y., Harrison, Lynn, Nestorova, Gergana G.]
通讯作者: Nestorova, Gergana G.
Growth hormone-releasing hormone antagonists counteract hydrogen peroxide - induced paracellular hyperpermeability in endothelial cells.
生长激素释放激素拮抗剂可以抵消过氧化氢诱导的内皮细胞旁细胞通透性过高。
DOI: 10.1016/j.ghir.2023.101534
发表时间: 2023
期刊: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society
影响因子: --
作者: [Barabutis,Nektarios, Siejka,Agnieszka, Akhter,MohammadS]
通讯作者: Akhter,MohammadS
The effect of androgen exposure on cerebral lateralization in the American alligator (Alligator mississippiensis).
雄激素暴露对美洲短吻鳄(密西西比短吻鳄)大脑偏侧化的影响。
DOI: 10.1016/j.ygcen.2023.114248
发表时间: 2023
期刊: General and comparative endocrinology
影响因子: 2.7
作者: [Honan,Caroline, Murray,ChristopherM]
通讯作者: Murray,ChristopherM
DOI: 10.1016/j.tem.2021.03.001
发表时间: 2021-06
期刊: Trends in endocrinology and metabolism: TEM
影响因子: --
作者: [Barabutis N]
通讯作者: Barabutis N
85
    National IDeA Symposium of Biomedical Research Excellence - NISBRE
    Molecular Biology and Immunopathology Core
    Molecular Biology and Immunopathology Core
    Molecular Biology
    海外基金