CENTER FOR PERCEPTION AND COMMUNICATION IN CHILDREN

项目摘要/摘要 总而言之：儿童感知和交流中心 我们的儿童感知与交流中心(CPCC)第二阶段的目标是 奥马哈男童镇国立研究医院(BTNRH)的生物医学研究卓越奖(Cobre)， 内布拉斯加州，是扩大目前的研究计划的范围，为 对确定影响机制和因素感兴趣的初级教员的发展 儿童的听觉和视觉感知与交流发展。这一重点反映了一种迫切的需求 用于翻译，多学科研究，调查患有沟通障碍的儿童的结果。 我们的目标是继续扩大我们的研究项目的范围，最终成为全国的领导者 研究有沟通能力的儿童的言语、语言、听力和认知发展 精神错乱。我们实现这一目标的方法是建立和支持独立、但互补的 针对(1)影响言语、语言、听力和认知的因素的研究项目 发展，(2)儿童听力损失和语言发育障碍对言语的影响， 真实世界环境中的语言、听力和认知功能，以及(3)改善儿童 言语、语言、听力和认知结果。我们将通过开发和支持关键的 美国国立卫生研究院资助的大量研究项目集中在与儿童感知和交流相关的问题上。 我们还将在第二阶段加强核心销售线索可用的研究基础设施，并扩展用户 这些资源的基础包括CPCC现有的调查人员。 第二阶段的四个初始项目将调查与以下相关的问题：(1)促进 人工耳蜗术后听者的言语理解：(2)儿童的鉴别诊断和预后 中耳炎，(3)听觉-视觉基础的知觉和语言机制的年龄效应 语音增强，以及(4)儿童克服困难的排练策略的个体差异 工作记忆的局限性。关于这些主题的研究将由三个核心推动。核心A，AN 行政核心，将协调与外部咨询委员会、行政管理委员会的互动 咨询委员会、内部执行委员会和研究导师。核心B，技术核心， 将为硬件和软件开发、数据分析和房间声学问题提供支持。核心C， 人类受试者核心，将收集临床数据，实施质量保证程序，并协助 临床措施的选择和解释以及研究研究参与者的招募。这个 CPCC将继续受益于高级教员的综合研究经验，他们将担任 核心领导和导师，以及来自独特的患者资源和翻译研究环境 BTNRH。

PROJECT SUMMARY/ABSTRACT OVERALL: CENTER FOR PERCEPTION AND COMMUNICATION IN CHILDREN The goal of Phase II of the Center for Perception and Communication in Children (CPCC), our Center of Biomedical Research Excellence (COBRE) at the Boys Town National Research Hospital (BTNRH) in Omaha, Nebraska, is to expand the range of the current research program by providing a unique environment for the development of junior faculty who have an interest in identifying mechanisms and factors that influence children’s auditory and visual perception and communicative development. This focus reflects a critical need for translational, multi-disciplinary research investigating outcomes for children with communication disorders. Our goal is to continue to expand the scope of our research programs, ultimately becoming the national leader for research on speech, language, hearing, and cognitive development in children with communication disorders. Our approach for achieving this goal is to build and support independent, yet complementary, research programs that address (1) factors that influence speech, language, hearing, and cognitive development, (2) the impact of childhood hearing loss and developmental language disorders on speech, language, hearing, and cognitive functions in real-world environments, and (3) strategies to improve children’s speech, language, hearing, and cognitive outcomes. We will do this by developing and supporting a critical mass of NIH-funded research programs focused on issues related to perception and communication in children. We will also strengthen the research infrastructure available to Core Leads in Phase II, and extend the user base of these resources to include established CPCC investigators. The four initial projects in Phase II will investigate issues related to (1) cognitive mechanisms that facilitate speech understanding for listeners with cochlear implants, (2) differential diagnosis and outcomes for children with otitis media, (3) age effects in the perceptual and linguistic mechanisms that underlie auditory-visual speech enhancement, and (4) individual differences in the rehearsal strategies used by children to overcome working memory limitations. Research on these topics will be facilitated by three cores. Core A, the an Administrative Core, will coordinate interaction with an External Advisory Committee, an Administrative Advisory Committee, an internal Executive Committee, and research mentors. Core B, the Technology Core, will provide support for hardware and software development, data analysis, and room-acoustics issues. Core C, the Human Subjects Core, will collect clinical data, implement quality assurance procedures, and assist with selection and interpretation of clinical measures and recruitment of participants for research studies. The CPCC will continue to benefit from the combined research experience of the senior faculty who will serve as Core Leads and mentors, and from the unique patient resources and translational research environment at BTNRH.