Duke Summer Training in Academic Research (Duke's STAR)

杜克大学夏季学术研究培训（杜克大学之星）

• 批准号: 10614911
• 负责人: DANIEL K. BENJAMIN
• 金额: $ 10.78万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10614911
• 关键词: Adverse event; Biometry; Child; Child Health; Childhood; Clinical Pharmacology; Clinical Research; Clinical Trials; Communication; Communities; Complement; Continuing Education; Data; Databases; Dose; Drug Kinetics; Education; Education Projects; Environment; Epidemiology; Faculty; Foundations; Funding; Future; Goals; High School Faculty; High School Student; Infant; Infrastructure; Instruction; Journals; Knowledge; Leadership; Learning; Link; Manuscripts; Medical; Medical Students; Mentors; Mentorship; Methods; National Center for Advancing Translational Sciences; National Institute of Child Health and Human Development; Nature; Network Infrastructure; Online Systems; Oral; Outcome; Participant; Pediatric Research; Pediatrics; Peer Review; Pharmaceutical Preparations; Pharmacoepidemiology; Physiology; Population Scientist Supplement (R25); Positioning Attribute; Principal Investigator; Process; Publications; Publishing; Qualifying; Recording of previous events; Research; Research Institute; Research Methodology; Research Personnel; Resources; Review Literature; Running; Safety; Schools; Science; Scientist; Series; Solid; Students; Therapeutic; Time; Training; Training Programs; Training Support; Underrepresented Minority; United States; United States National Institutes of Health; Universities; Work; Writing; body system; career; disadvantaged student; drug efficacy; drug metabolism; education research; experience; faculty mentor; graduate school preparation; high risk; high school; improved; knowledge base; meetings; member; mid-career faculty; older patient; organ growth; peer; prevent; programs; project-based learning; recruit; research faculty; science teacher; skills; success; summer program; summer research; teacher; text searching; tutoring; undergraduate research experience; undergraduate student; university student

The proposed Duke Summer Training in Academic Research program (referred to henceforth as “Duke's STAR” program) will provide a high-quality research experience for undergraduate students, high school students, and high school teachers during the summer academic break. The program will help attract young students to careers in science; provide opportunities for students to gain valuable research experience in preparation for graduate school; and enhance the skills of science teachers, enabling them to more effectively communicate the nature of the scientific process to their students. The proposed summer research program will expand and complement existing NIH-sponsored training programs already in place at Duke University under the leadership of the principal investigator, Daniel K. Benjamin Jr. As chair of the Pediatric Trials Network, Dr. Benjamin has broad oversight of 3–6 large pharmacoepidemiology projects every year, each of which requires well-defined, short-term, pre-study work that is ideally suited for a 9-week summer research experience and, as we have demonstrated with our previous R25 program, will result in publications for trainees. In addition, the Duke Clinical Research Institute (DCRI) offers formal educational and support programs for junior faculty, fellows, residents, and medical students with funding from internal DCRI resources as well as the NIH. The proposed program represents a critical piece in a continuum of NIH-supported training at the DCRI that runs the gamut from the high school level to mid-career faculty. In short, the program will be uniquely positioned within an established educational infrastructure with a track record of successful trainees. The summer research experience will take place over 9 weeks and will focus on pharmacoepidemiological research methodology and writing skills. Participants will be paired with Duke faculty to work on an original, hypothesis-driven project. For the first 2 weeks of the program, trainees will work with their faculty mentors to develop a solid knowledge base of a specific pharmacoepidemiologic question based on a thorough review of the literature. During weeks 2–8, the trainees will work in groups to develop a 6–10-page manuscript consisting of a description of the research question, specific aims, methods, and figures/tables for the study. During the final 2 weeks, trainees will refine their manuscripts and prepare oral presentations of their findings. Throughout this time, a medical writer will provide trainees with didactic instruction via small group sessions. Trainees will also work with their mentors throughout the course of the program to review their progress. At the program's conclusion, trainees will present the results of their work at the DCRI before an audience of their peers, pediatrics faculty and fellows, and other community members. Finally, trainees will be followed for 10 years using a web-based database to assess the training program's impact on their subsequent academic and professional trajectories. The proposed program will result in an improved pipeline of future scientists whose practical experience in pediatric clinical research will facilitate their entry into research careers.

拟议中的杜克暑期学术研究培训计划（以下简称“杜克的 星星”计划）将为本科生、高中生提供高质量的研究体验 学生和高中教师在暑假期间。该计划将有助于吸引年轻人 学生在科学事业;为学生提供机会，以获得宝贵的研究经验， 为研究生院做准备;提高科学教师的技能，使他们能够更有效地 向学生传达科学过程的本质。暑期研究计划 将扩展和补充杜克大学现有的NIH赞助的培训项目 在首席研究员丹尼尔K.小本杰明作为儿科试验的主席 网络，本杰明博士每年有3-6个大型药物流行病学项目的广泛监督， 这需要明确的，短期的，研究前的工作，非常适合为期9周的夏季研究 经验，正如我们在之前的R25计划中所展示的那样，将导致以下出版物： 实习生此外，杜克临床研究所（DCRI）提供正规的教育和支持 初级教师，研究员，居民和医学生的计划，由DCRI内部资源提供资金 以及NIH。拟议的计划代表了NIH支持的连续培训的关键部分 在DCRI，从高中到职业中期的教师。简而言之，该计划将 在已建立的教育基础设施中具有独特的地位，并有成功的学员记录。 夏季研究经验将在9周内进行，重点是药物流行病学 研究方法和写作技巧。参与者将与杜克教师配对， 假设驱动项目。在课程的前两周，学员将与他们的教师导师合作， 基于对以下内容的全面审查，建立特定药物流行病学问题的坚实知识基础 文学作品在第2-8周，学员将分组工作，以制定一个6-10页的手稿， 说明研究问题、具体目标、方法和研究的图表。期间 最后两周，受训人员将修改他们的手稿，并准备口头报告他们的调查结果。在整个 今次，一名医学作家将以小组形式为学员提供教学指导。学员将 在整个课程过程中，他们也与导师一起工作，以审查他们的进展。在节目的 最后，受训人员将在DCRI向同行观众展示他们的工作成果， 儿科教师和研究员，以及其他社区成员。最后，学员将被跟踪10年 使用基于网络的数据库来评估培训计划对他们随后的学术和 职业轨迹拟议中的计划将导致未来科学家的改善管道， 儿科临床研究的实践经验将有助于他们进入研究生涯。

项目成果

Diagnostic Utility of Cerebrospinal Fluid White Blood Cell Components for the Identification of Bacterial Meningitis in Infants.

脑脊液白细胞成分在婴儿细菌性脑膜炎鉴定中的诊断效用。

• DOI: 10.1093/jpids/piad087
• 发表时间: 2023
• 期刊: Journal of the Pediatric Infectious Diseases Society
• 影响因子: 3.2
• 作者: Lamb,AshleyE;Rent,Sharla;Brannon,AsiaJ;Greer,JonathanL;Ndey-Bongo,NyssaP;Cho,StephenH;Greenberg,RachelG;BenjaminJr,DanielK;Clark,ReeseH;Kumar,KaranR
• 通讯作者: Kumar,KaranR

Early-onset sepsis in term infants admitted to neonatal intensive care units (2011-2016).

• DOI: 10.1038/s41372-020-00860-3
• 发表时间: 2021-01
• 期刊: Journal of perinatology : official journal of the California Perinatal Association
• 作者: Polcwiartek LB;Smith PB;Benjamin DK;Zimmerman K;Love A;Tiu L;Murray S;Kang P;Ebbesen F;Hagstrøm S;Clark RH;Greenberg RG
• 通讯作者: Greenberg RG

Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge.

新生儿重症监护室庆大霉素暴露和出院时听力功能的评估。

• DOI: 10.1016/j.jpeds.2018.07.101
• 发表时间: 2018
• 期刊: The Journal of pediatrics
• 作者: Puia-Dumitrescu,Mihai;Bretzius,OliviaM;Brown,Nia;Fitz-Henley,JamesA;Ssengonzi,Rebecca;Wechsler,CarolineS;Gray,KeyariaD;BenjaminSr,DanielK;Smith,PBrian;Clark,ReeseH;Gonzalez,Daniel;Hornik,ChristophP
• 通讯作者: Hornik,ChristophP

In-hospital outcomes of premature infants with severe bronchopulmonary dysplasia.

• DOI: 10.1038/jp.2017.49
• 发表时间: 2017-07
• 期刊: Journal of perinatology : official journal of the California Perinatal Association
• 作者: Jackson W;Hornik CP;Messina JA;Guglielmo K;Watwe A;Delancy G;Valdez A;MacArthur T;Peter-Wohl S;Smith PB;Tolia VN;Laughon MM
• 通讯作者: Laughon MM

Safety of histamine-2 receptor blockers in hospitalized VLBW infants.

• DOI: 10.1016/j.earlhumdev.2016.05.010
• 发表时间: 2016-08
• 期刊: Early human development
• 影响因子: 2.5
• 作者: Romaine A;Ye D;Ao Z;Fang F;Johnson O;Blake T;Benjamin DK Jr;Cotten CM;Testoni D;Clark RH;Chu VH;Smith PB;Hornik CP;Best Pharmaceuticals for Children Act – Pediatric Trials Network
• 通讯作者: Best Pharmaceuticals for Children Act – Pediatric Trials Network