UCSF Environmental Research and Translation for Health Center (EaRTH Center)

加州大学旧金山分校健康中心环境研究与翻译（EaRTH 中心）

• 批准号: 10598480
• 负责人: Tracey J. Woodruff
• 金额: $ 131.45万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-05-22 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10598480
• 关键词: Acceleration; Address; Affect; Analytical Chemistry; Bioinformatics; Biological; Biological Assay; Biomedical Research; California; Cell Nucleus; Cells; Chemical Exposure; Chemicals; Child; Chronic Disease; Clinical; Clinical Medicine; Clinical Research; Clinical Sciences; Collaborations; Communication; Communities; Community Outreach; Complex; Consultations; Core Facility; Data; Dentistry; Development; Diabetes Mellitus; Discipline; Discipline of Nursing; Disease; Education; Educational Curriculum; Environment; Environmental Exposure; Environmental Health; Environmental Risk Factor; Epidemiology; Exposure to; Family; Funding; Future; Goals; Health; Health Professional; Health Resources; Health Sciences; Health education; Healthcare; Human; Infrastructure; Institution; International; Intervention; Investigation; Laboratories; Leadership; Link; Location; Longevity; Malignant Neoplasms; Measurement; Measures; Mediating; Medical; Medical Students; Medicine; Mentors; Mentorship; Modeling; National Institute of Environmental Health Sciences; Neurodevelopmental Disorder; Obesity; Pathway interactions; Patients; Peer Review; Pharmacy facility; Pilot Projects; Positioning Attribute; Prevalence; Prevention; Production; Proteomics; Publishing; Reproduction; Reproductive Health; Research; Research Design; Research Personnel; Resources; Role; San Francisco; Schools; Science; Scientist; Students; Technology; Translating; Translational Research; Translations; Underserved Population; Universities; Vulnerable Populations; Women' s Health; Work; career; clinical training; community engagement; data integration; environmental chemical; environmental stressor; health data; health literacy; healthcare community; high throughput screening; human tissue; improved; in vivo; insight; interdisciplinary collaboration; member; men; mobile computing; model organism; next generation; operation; outreach; prevent; programs; reproductive; social stressor; tool

The overall goal of the new University of California, San Francisco (UCSF) Environmental Research and Translation for Health (EaRTH) Center is to accelerate the pace of recognizing and preventing environmental exposures that affect reproduction and development to improve human health across the lifespan. Addressing the complex problems of environmental health requires partnerships across disciplines; mobilization of technology for identification, intervention, and prevention; and education of future scientists and clinicians and the public. The EaRTH Center is uniquely positioned to address these challenges and advance environmental health. By virtue of its location at UCSF—a premier institution for biomedical research, translation of research findings, and clinical training—and its strong interdisciplinary team, the EaRTH Center will fill a critical gap in a prominent clinical and biomedical research setting. Our proposed UCSF P30 EaRTH Center will allow us to: create opportunities for new research directions in environmental health at UCSF that are not currently possible; nurture and sustain transdisciplinary research collaborations across a network of academics and diverse UCSF departments to advance our understanding of the relationship between environment and disease; mentor and grow the next generation of research and clinical leaders in environmental health; and embed environmental health literacy within health care to accelerate prevention of environmentally mediated diseases. Our Center tightly integrates 4 cores and 1 program: 1) an Administrative Core to provide leadership, infrastructure, administrative and communication support, advice and oversight to coordinate all EaRTH Center operations; 2) an Integrated Health Sciences Facility Core (IHSFC) that will provide consultation on study design, data integration, data of environmental and social stressors, and translation and dissemination of research findings; 3) a Bioassay Facility Core that will provide state-of-the-art tools for measuring chemical exposures and their effects on biological pathways; 4) a Community Engagement Core (CEC) to expand environmental health education and resources for students and health professionals to embed environmental health within health care; and 5) a Pilot Project Program to fund transdisciplinary projects enabling researchers to enter the field or add an environmental component to their current research. Our integrated Center will lead to new scientific understandings in environmental health tightly linked to our community outreach work, which will shift the fundamental understanding of the role of environment in disease, leading to solutions to preventing harmful exposures and improving health.

新成立的加州大学旧金山分校(UCSF)环境研究的总体目标 而翻译为健康(地球)中心是为了加快识别和预防的步伐 影响生殖和发育的环境暴露，以改善人类一生的健康。 解决环境健康的复杂问题需要跨学科的伙伴关系；动员 用于识别、干预和预防的技术；以及对未来科学家和临床医生的教育 公众。地球中心在应对这些挑战和促进环境保护方面具有独特的地位 健康。凭借其在加州大学旧金山分校的位置-一流的生物医学研究机构，研究成果的翻译 研究结果和临床培训-及其强大的跨学科团队，地球中心将填补 突出的临床和生物医学研究环境。我们拟建的加州大学旧金山分校P30地球中心将允许我们： 为加州大学旧金山分校在环境健康方面的新研究方向创造机会，这是目前不可能的； 在学术网络和不同的加州大学旧金山分校培养和维持跨学科研究合作 促进我们对环境与疾病之间关系的认识；指导和 培养环境健康领域的下一代研究和临床领导者；并将环境 在卫生保健中普及卫生知识，以加速预防环境介导性疾病。我们的中心 紧密集成4个核心和1个计划：1)管理核心，以提供领导力、基础设施、 行政和通信支助、咨询和监督，以协调地球中心的所有业务；2) 综合健康科学设施核心(IHSFC)，将提供研究设计、数据方面的咨询 整合环境和社会应激源的数据，翻译和传播研究成果； 3)生物分析设施核心，将提供最先进的工具来测量化学暴露及其 对生物途径的影响；4)社区参与核心(CEC)，以扩大环境健康 为学生和卫生专业人员提供教育和资源，将环境卫生纳入卫生保健； 5)试点项目计划，资助跨学科项目，使研究人员能够进入该领域或增加 在他们目前的研究中加入了环境因素。我们的综合中心将带来新的科学 对环境健康的理解与我们的社区外展工作紧密相连，这将使 对环境在疾病中的作用的基本理解，导致预防有害的解决方案 暴露和改善健康。