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Novel Muscle Therapeutics Through Selective Beta-Adrenoceptor Signalling

Novel Muscle Therapeutics Through Selective Beta-Adrenoceptor Signalling
通过选择性β-肾上腺素受体信号传导的新型肌肉疗法
批准号:
nhmrc : 1026231
负责人:
A/Pr Paul Gregorevic
金额:
$40.25万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2012
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2012-01-01 至 2015-12-31

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中文摘要
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英文摘要
Muscle wasting is an urgent and unmet health risk commonly associated with ageing; cancer, muscle diseases, and conditions including cardiovascular and metabolic disorders. Manipulating beta-adrenergic signalling is a therapeutic target for muscle wasting but treatments have so far been limited due to cardiaovascular side effects. Using cutting edge technologies, we will identify treatments that effectively separate beneficial effects on skeletal muscles from unwanted effects on the heart.
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