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The effects of ACTN3 R577X on muscle wasting and repair, and response to therapy

The effects of ACTN3 R577X on muscle wasting and repair, and response to therapy
ACTN3 R577X 对肌肉消耗和修复以及治疗反应的影响
批准号:
nhmrc : GNT1130215
负责人:
A/Pr Paul Gregorevic
金额:
$106.61万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2017
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2017-01-01 至 --

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中文摘要
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英文摘要
Complete loss of ACTN3 is normal and occurs in 1 in 5 people world-wide. While it does not cause disease, loss of ACTN3 results in ~10% reduction in muscle mass and strength. This has tremendous impact not only on the success of elite athletes but also the quality of life in people who are already frail. Precisely how ACTN3 affects muscle mass is unclear. Understanding this will help identify the patients who are at greater risk of muscle wasting and also the therapies that will best treat them.
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Rescuing the dystrophin-glycoprotein complex to protect muscles from wasting conditions
  • 批准号:
    nhmrc : GNT1144772
  • 项目类别:
    Project Grants
  • 资助金额:
    $83.33万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Paul Gregorevic
  • 依托单位:
Rescuing the dystrophin-glycoprotein complex to protect muscles from wasting conditions
  • 批准号:
    nhmrc : 1144772
  • 项目类别:
    Project Grants
  • 资助金额:
    $56.35万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Paul Gregorevic
  • 依托单位:
The effects of ACTN3 R577X on muscle wasting and repair, and response to therapy
  • 批准号:
    nhmrc : 1130215
  • 项目类别:
    Project Grants
  • 资助金额:
    $72.83万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Paul Gregorevic
  • 依托单位:
Investigating follistatin-based interventions for long term-protection against frailty associated with chronic illness and aging
  • 批准号:
    nhmrc : GNT1121500
  • 项目类别:
    Project Grants
  • 资助金额:
    $98.72万
  • 财政年份:
    2017
  • 负责人:
    A/Pr Paul Gregorevic
  • 依托单位:
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