Developmental Trajectories to Stuttering Persistence and Recovery
口吃持续和恢复的发展轨迹
基本信息
- 批准号:10624921
- 负责人:
- 金额:$ 62.31万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-06-01 至 2025-05-31
- 项目状态:未结题
- 来源:
- 关键词:AccelerationAchievementAddressAdoptedAdultAffectAgeAnxietyArousalAssessment toolAttitudeAwarenessBehavioralBiological MarkersBrainBrain imagingBrain regionChildChildhoodChronicClinicalCognitiveCommunicationCouplingCross-Sectional StudiesDataDevelopmentDiagnosticDiseaseEmotionalEmotionsEquationEtiologyGoalsGuidelinesIndividualInfluentialsInterventionLeadLearningLife ExperienceLightLinguisticsLinkLongitudinal StudiesMapsMissionModelingNeurologicNursery SchoolsOutcomeOutputPathway interactionsPerformancePersonsPhysiologicalPreschool ChildPreventionPrevention strategyProductionQuality of lifeRecoveryResearchResourcesRiskRisk FactorsRisk MarkerRoleSchool-Age PopulationScientistSeveritiesSpeechSpeech-Language PathologyStutteringSympathetic Nervous SystemTechniquesTestingTimeTranslatingUnited States National Institutes of HealthVariantVocationadverse outcomecombinatorialemotional factorexperiencefunctional near infrared spectroscopyhemodynamicsimaging modalityimprintimprovedinsightlongitudinal designneuralneuroimagingneurophysiologynovelnovel therapeutic interventionpsychosocial developmentresponseskillstreatment strategy
项目摘要
Summary
Stuttering or childhood onset fluency disorder, affects 5-8% of preschool-aged children. Although many
children’s stuttering resolves within 12-24 months of onset, those who continue to stutter beyond age 7 are at
significant risk for chronic stuttering. For children who persist, speaking often becomes a lifelong struggle. The
negative consequences for academic/vocational achievement and psychosocial development suffered by
many of these children are substantial and long lasting.
Prior studies in preschool children who stutter (CWS) have identified demographic, behavioral, and
physiological factors associated with stuttering persistence by comparing performance across groups of
preschool children. Yet, we do not know how a child’s unique developmental pathway leads them to recover or
persist in stuttering. This limits our ability to predict a child’s risk of developing persistent (chronic) stuttering
reliably and to develop efficacious prevention and treatment strategies.
This project shifts experimental focus, for the first time, to the individual child, providing a dynamic
account of how neurological, behavioral, and experiential factors unfold over time and contribute to different
stuttering outcomes. We achieve this through our comprehensive, longitudinal design and structural equation
modeling framework, in which we map the developmental trajectories of critical factors implicated in stuttering.
In our approach, we use a novel neuroimaging technique, functional near-infrared spectroscopy (fNIRS), that
allows us to record brain activity concurrent with continuous speech production, a distinct advantage of this
technique. We will assess whether neural markers derived from fNIRS recordings identified in our research
with older CWS can distinguish preschool children at risk for persistence, thereby helping to establish a neural
basis for stuttering persistence and recovery. We will also assess whether atypical coupling between
sympathetic nervous system activity and speech output, detected in cross-sectional studies, represents a risk
factor for chronic stuttering. Finally, stuttering leaves a lasting imprint on children who persist. Ample evidence
shows that older children and adults are more likely to harbor negative emotions about their speech and/or
develop communication anxiety. We lack a continuous picture, however, of how these issues develop in young
children whose awareness of stuttering is emerging. We will examine how behavioral, emotional, and
experiential factors unfold over time and explore their roles in stuttering persistence or recovery and in the
development of negative communication attitudes.
This project will bring new, comprehensive insights into why stuttering persists in individual children,
and, in parallel, help better prioritize therapy resources, identify etiological targets for prevention and
intervention, and accelerate the development of new treatments.
总结
项目成果
期刊论文数量(0)
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{{ truncateString('BRIDGET M WALSH', 18)}}的其他基金
Developmental Trajectories to Stuttering Persistence and Recovery
口吃持续和恢复的发展轨迹
- 批准号:
9973268 - 财政年份:2020
- 资助金额:
$ 62.31万 - 项目类别:
Developmental Trajectories to Stuttering Persistence and Recovery
口吃持续和恢复的发展轨迹
- 批准号:
10377110 - 财政年份:2020
- 资助金额:
$ 62.31万 - 项目类别:
Developmental Trajectories to Stuttering Persistence and Recovery
口吃持续和恢复的发展轨迹
- 批准号:
10728444 - 财政年份:2020
- 资助金额:
$ 62.31万 - 项目类别:
Developmental Trajectories to Stuttering Persistence and Recovery
口吃持续和恢复的发展轨迹
- 批准号:
10408693 - 财政年份:2020
- 资助金额:
$ 62.31万 - 项目类别:
Developmental Trajectories to Stuttering Persistence and Recovery
口吃持续和恢复的发展轨迹
- 批准号:
10594623 - 财政年份:2020
- 资助金额:
$ 62.31万 - 项目类别:
Central and Peripheral Dynamics of Speech Production in Children Who Stutter
口吃儿童言语产生的中枢和外周动态
- 批准号:
8690439 - 财政年份:2014
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$ 62.31万 - 项目类别:
Language and Motor Interactions in Parkinson's Disease
帕金森病的语言和运动相互作用
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7038336 - 财政年份:2005
- 资助金额:
$ 62.31万 - 项目类别:
Language and Motor Interactions in Parkinson's Disease
帕金森病的语言和运动相互作用
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6936907 - 财政年份:2005
- 资助金额:
$ 62.31万 - 项目类别:
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