Brief Research In Aging and Interdisciplinary Neurosciences (BRAIN)

项目总结 哥伦比亚大学医学中心的神经病学系是多学科的丰富场所 神经学研究，特别关注与老化神经系统相关的疾病。这 一项提案寻求继续资助25名临床前学生参加#年简要研究的职位 老龄化和跨学科神经科学(脑)课程每年夏天。对于大脑计划，我们有 在早期为博士前学生开发了一种全面的方法来开发正式的研究计划 在生物医学、行为和临床研究方面发展事业。这项工作是以合作的方式进行的 通过简短但密集的指导暑期研究，为这些学生提供培训经验。这项研究 培训通过在该领域的持续研究提供基础、行为和临床研究的机会 基础神经科学、神经病理学、神经遗传学、神经心理学、中风、阿尔茨海默病和 相关障碍、运动神经元病、帕金森病和相关障碍、癫痫以及 治疗这些疾病患者的神经学临床试验。此外，一项全面的结构化研究 教育课程是在密集的研究体验过程中提供的，主题包括 负责任地进行研究和方法，以提高重现性、基本研究方法、 摘要作者简介和海报演示文稿，以及统计概念和 分析方法，以及最常见神经病学的流行病学和病理生理学综述 与衰老相关的疾病，因此有可能被研究。我们的机构拥有最好的记录， 培养世界各地的学术神经学家，这一短期、密集的计划建立在 这一丰富的资源通过实践介绍神经学研究，全面回顾 研究原理，从而确保这些学生有最好的机会在 并准备开发自己的研究项目。

Project summary The Department of Neurology at Columbia University Medical Center serves as a rich site for multidisciplinary neurological research, with particular focus on disorders associated with the aging nervous system. This proposal seeks to continue funding for positions for 25 preclinical students participating in the Brief Research in Aging and Interdisciplinary Neurosciences (BRAIN) program each summer. For the BRAIN program, we have developed a comprehensive approach to develop a formal research program for predoctoral students early in developing careers in biomedical, behavioral and clinical research. The work is collaboratively approached through brief but intensive mentored summer research training experiences for these students. The research training provides opportunities in basic, behavioral and clinical research through ongoing research in the fields of basic neuroscience, neuropathology, neurogenetics, neuropsychology, stroke, Alzheimer disease and related disorders, motor neuron disease, Parkinson disease and related disorders, and epilepsy, as well as neurologic clinical trials treating patients with these disorders. In addition, a comprehensive structured research education curriculum is delivered over the course of the intense research experience, with topics including responsible conduct of research and methods to enhance reproducibility, basic research methodologies, introductions to abstract authorship and poster presentations, and introduction of statistical concepts and approach to analyses, as well as epidemiologic and pathophysiologic reviews of the most common neurologic disorders associated with aging and thus likely to be studied. Our institution has the strongest track record of developing academic neurologists of anywhere worldwide, and this short-term, intense program builds upon this wealth of resources through hands-on introductions to neurological research, comprehensive review of principles of research, and thus assures the best opportunity for these students to develop research careers in the field and be prepared to developing research projects of their own.