Alzheimer's Disease and Related Dementias Innovation Incubator (InnovaTor)

项目摘要/摘要 阿尔茨海默病和相关痴呆症(ADRD)是对公共卫生日益严峻的挑战， 可通过以下方式满足的未得到满足的需求：具体目标1)创新和创业；具体目标2) 以非学术研究为基础的职业；以及特定目标3)学术ADRD药物开发。这三个人 主题将在研讨会、实习、亲身体验、讨论和监督项目中展开 UNLV脑健康创新孵化器(创新者)。创新者将由首席调查员共同领导 (PI)Jeffrey Cummings，医学博士，SCD，经验丰富的ADRD调查员和试验者，Pi Jamie Schwartz，MBA， 联合国志愿人员组织经济发展办公室工业和商业参与主任 科学-商业领导团队。创新者将成为帮助学生识别研究产品的平台 有商业价值，保护知识产权，创办初创公司，获得资金，促进 商业化，并推进营销活动(具体目标1)。该课程将包括 介绍SBIR和STTR赠款的发展。除了正在进行的研讨会外，为期一周的暑期 让UNLV学生和其他人参与讨论、项目和团队的创业沉浸式体验 演练将由创新者主持。一年一度的创新日将包括全校范围的活动，以吸引 为创新者提供培训，并为与可持续发展发展相关的创业机会提供见解。 有关非学术职业选择的讨论将由在政府科学领域担任职务的个人领导 行政、宣传、非营利组织、科学写作和编辑、政策智库和投资 (具体目标2)。创新者与礼来公司建立了战略联盟，以拥有行业- 基础教员与参与者互动，并就生物制药方面的研究职业进行培训。药效 发展讨论将强调与相关初创企业和 创业机会(具体目标3)。创新者俱乐部将由现在和过去的创新者组成 与会者鼓励创业，并支持不断发展的初创企业社区。敏捷的创新者 该结构将由一个指导委员会、外部咨询委员会和一个评估小组提供支助。已定义 里程碑将指导创新者的发展。对联合国志愿人员方案以及其他方案的宣传 南内华达州的教育机构将由一个创新领航员领导，其中包括一个吸引 本科生(CubaTor之前)。UNLV既是一个为拉美裔服务的机构，也是一个亚裔美国人 和美洲原住民太平洋岛民服务机构提供机会建立项目以吸引 开展少数民族学生创新活动。创新者将与NIH和NSF资助的项目在 联合国志愿人员组织、联合国志愿人员组织创新资源(李商学院、博伊德法学院、经济办公室 (发展)，以及当地社区生物技术公司和组织。大脑健康创新者将 建设一种致力于ADRD的创新创业文化。

PROJECT SUMMARY/ABSTRACT Alzheimer’s Disease and Related Dementias (ADRD) are growing challenges to the public health and have unmet needs that can be addressed through: Specific Aim 1) innovation and entrepreneurship; Specific Aim 2) non-academic research-based careers; and Specific Aim 3) academic ADRD drug development. These three themes will be developed in seminars, internships, lived experiences, discussions, and supervised projects of the UNLV Brain Health Innovation Incubator (InnovaTor). The InnovaTor will be Co-Led by Principal Investigator (PI) Jeffrey Cummings, MD, ScD, an experienced ADRD investigator and trialist and PI Jamie Schwartz, MBA, Director of Industry and Business Engagement for the UNLV Office of Economic Development to create a science-business leadership team. The InnovaTor will be a platform to help students identify research products that have commercial value, protect intellectual property, initiate a start-up company, secure funding, promote commercialization, and advance a marketing campaign (Specific Aim 1). The curriculum will include an introduction to SBIR and STTR grant development. In addition to on-going seminars, a 1-week summer Entrepreneurship Immersion Experience engaging UNLV students and others in discussions, projects, and team exercises will be hosted by the InnovaTor. An annual Innovation Day will involve campus-wide activities to attract participants to the InnovaTor and provide insights into the opportunities for ADRD-related entrepreneurship. Discussions of non-academic career alternatives will be led by individuals with roles in government science administration, advocacy, non-profit organizations, science writing and editing, policy think tanks, and investment (Specific Aim 2). The InnovaTor has established a strategic alliance with Eli Lilly and Company to have industry- based faculty interact with participants and educate about research-based careers in biopharma. Drug development discussions will emphasize the academic-industry interface with associated start-up and entrepreneurial opportunities (Specific Aim 3). An Innovator Club will be comprised of current and past InnovaTor participants to encourage entrepreneurship and to support an evolving start-up community. An agile InnovaTor structure will be supported by a Steering Committee, External Advisory Board, and an assessment team. Defined milestones will guide the development of the InnovaTor. Outreach to UNLV programs as well as other educational institutions in Southern Nevada will be led by an Innovation NavigaTor including a program to attract undergraduate students (Pre-CubaTor). UNLV is both a Hispanic-Serving Institution and an Asian American and Native American Pacific Islander-Serving Institution providing an opportunity to build programs to attract minority students to InnovaTor activities. The InnovaTor will interact with NIH and NSF-funded programs at UNLV, UNLV innovation resources (Lee Business School, Boyd School of Law, Office of Economic Development), and local community biotechnology firms and organizations. The Brain Health InnovaTor will build a culture of innovation and entrepreneurship devoted to ADRD.