Center for Environmental and Health Effects of PFAS

PFAS 环境与健康影响中心

• 批准号: 10747757
• 负责人: CAROLYN J MATTINGLY
• 金额: $ 73万
• 依托单位: NORTH CAROLINA STATE UNIVERSITY RALEIGH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-19 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10747757
• 关键词: Address; Animals; Area; Back; Blood; Blood Tests; Blood specimen; Categories; Chemicals; Collection; Communities; Diagnostic Reagent Kits; Engineering; Ensure; Fright; Funding; Future; Health; Health Professional; Human; Individual; Internet; Intervention; Laboratories; Location; Measures; Medical; Medicine; Methods; Nafion; National Health and Nutrition Examination Survey; Newsletter; North Carolina; Parents; Participant; Persons; Plants; Poly-fluoroalkyl substances; Public Health; Randomized; Recommendation; Recording of previous events; Reporting; Research Project Grants; Sampling; Self Administration; Serum; Superfund; Technology; Test Result; Testing; Thyroid Gland; Time; Training; United States National Academy of Sciences; Work; community engagement; comparison group; coronavirus disease; drinking water; exposed human population; field study; follow-up; high risk; improved; manufacture; member; novel; sample collection; self testing; social media; study population; substance use; water treatment; webinar

Abstract The NC State Center for Environmental and Health Effects of PFAS focuses on understanding the implications of PFAS exposure in humans and animals in the Cape Fear River Basin of North Carolina. The Cape Fear River in North Carolina is characterized by high levels of a variety of PFAS (per-and poly-fluoroalkyl substances) throughout the watershed. The specific chemicals vary by location with the lower Cape Fear characterized by the presence of novel fluoroethers from chemical manufacturing near Fayetteville, NC, while upstream, the levels of legacy PFAS such as PFOA and PFOS are elevated and frequently exceed the drinking water advisory levels for these chemicals. To better characterize the diversity of PFAS exposures among impacted communities along the Cape Fear River, we have developed this supplement proposal to: 1) further characterize human exposure in communities upriver from Fayetteville, 2) improve turnaround time for report back of PFAS blood results and evaluate a self-administered method for PFAS blood testing, and 3) expand community engagement regarding the recent National Academies of Sciences, Engineering, and Medicine recommendations for PFAS testing and medical management for communities throughout the Cape Fear River Basin.

摘要 北卡罗来纳州全氟辛烷磺酸环境和健康影响国家中心侧重于了解其影响 在北卡罗来纳州的开普福里河流域，人类和动物暴露于全氟辛烷磺酸的风险。恐惧角河流 在北卡罗来纳州，以各种全氟辛烷酸(全氟烷基和多氟烷基物质)含量较高为特征 在整个分水岭。特定的化学物质因地点不同而不同，下角恐惧的特征是 来自北卡罗来纳州费耶特维尔附近化学制造的新型氟醚的存在，而上游的水平 传统的全氟辛烷磺酸和全氟辛烷磺酸等全氟辛烷磺酸含量偏高，经常超过饮用水建议水平。 这些化学物质。为了更好地描述受影响社区中全氟辛烷磺酸暴露的多样性 在恐惧角河流，我们制定了这项补充建议，以：1)进一步描述人类暴露的特征 在费耶特维尔上游的社区，2)改善报告PFAS血液结果的周转时间，并 评估自我管理的全氟辛烷磺酸血液检测方法，以及3)扩大社区参与 美国国家科学院、工程院和医学研究院最近对全氟辛烷磺酸检测和 为整个开普费尔河流域的社区提供医疗管理。