Center for Environmental and Health Effects of PFAS

摘要 北卡罗来纳州全氟辛烷磺酸环境与健康影响国家中心侧重于了解 年在开普福里河流域接触全氟辛烷磺酸对人和动物的影响 北卡罗来纳州。北卡罗来纳州的开普费尔河的特点是高水平的 流域内各种全氟烷基化合物(全氟烷基物质和多氟烷基物质)。具体的 化学物质因地点不同而不同，下角恐惧以新奇的存在为特征 来自北卡罗来纳州费耶特维尔附近化学制造的氟醚，而上游， 传统的全氟辛烷酸和全氟辛烷磺酸等全氟辛烷磺酸含量升高，经常超过饮用水 这些化学品的建议水平。为了更好地描述全氟辛烷磺酸暴露的多样性 在开普敦恐惧河沿岸受影响的社区中，我们制定了这一补充方案 建议：1)进一步描述人类在费耶特维尔上游社区的暴露特征，2) 扩展分析能力以测量生物和环境中的总有机氟 样本，以及3)展示了新的血液采集方法的可行性，这些方法可以 在现场用于人和动物血液的全氟辛烷磺酸分析。

Abstract The NC State Center for Environmental and Health Effects of PFAS focuses on understanding the implications of PFAS exposure in humans and animals in the Cape Fear River Basin of North Carolina. The Cape Fear River in North Carolina is characterized by high levels of a variety of PFAS (per-and poly-fluoroalkyl substances) throughout the watershed. The specific chemicals vary by location with the lower Cape Fear characterized by the presence of novel fluoroethers from chemical manufacturing near Fayetteville, NC, while upstream, the levels of legacy PFAS such as PFOA and PFOS are elevated and frequently exceed the drinking water advisory levels for these chemicals. To better characterize the diversity of PFAS exposures among impacted communities along the Cape Fear River, we have developed this supplement proposal to: 1) further characterize human exposure in communities upriver from Fayetteville, 2) expand analytical capabilities to measure total organic fluorine in biological and environmental samples, and 3) demonstrate feasibility for novel blood collection methods that can be employed in the field for both human and animal blood PFAS analysis.