Activity Space Adversity and Racial Disparities in Adolescent Health

青少年健康中的活动空间逆境和种族差异

• 批准号: 10754093
• 负责人: Christopher R Browning
• 金额: $ 68.62万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10754093
• 关键词: Adolescence; Adolescent; Adolescent Development; Adult; Age; Area; Black race; C-reactive protein; COVID-19 pandemic; Caregivers; Chronic Disease; Communities; Data; Data Analyses; Data Collection; Data Sources; Development; Dimensions; Disparity; Ecological momentary assessment; Exhibits; Exposure to; Hair; Health; Heterogeneity; Home; Hydrocortisone; Individual; Inflammation; Inflammatory; Intervention; Investigation; Link; Location; Measures; Mediating; Mental Health; Neighborhoods; Outcome; Patient Self-Report; Perception; Personal Satisfaction; Phase; Physiological; Police; Process; Race; Reaction; Research; Resolution; Risk; Role; Safety; Sampling; Shapes; Stress; Structural Racism; Surveys; Time; Victimization; Violence; Work; Youth; adolescent health; behavioral health; children of color; cohort; design; experience; heart rate variability; innovation; killings; metropolitan; microaggression; neglect; novel; psychologic; racial difference; racial disparity; racial diversity; racial identity; response; segregation; stress reactivity; substance use; violence exposure

PROJECT SUMMARY Prior research has documented substantial differences in levels of physiological stress among Black- and White- identifying individuals during adolescence, a period of particular importance from a developmental perspective, which may shape disparities in chronic disease in adulthood. The proposed project seeks to explore the role of exposure to multiple dimensions of activity-space adversity (ASA) – including area-level violence, elevated policing, and racial exclusivity – in contributing to everyday (real-time) perceptions of both physical and psychological unsafety and their contribution to explaining racial physiological stress disparities during adolescence (Aim 1). We will also consider the impact of ASA exposures, unsafety perceptions, and physiological stress as predictors of substance use and mental health outcomes (Aim 2). We will explore the moderating influence of other-perceived race – or the degree to which an individual believes others perceive their race to be Black in public interactions – on ASA exposure and unsafety effects on physiological stress and health outcomes. The project will collect aim-relevant data on a racially diverse cohort of adolescents residing in the Columbus, OH metropolitan area employing an innovative two-stage design: The first phase will produce rich cross-sectional data (N=700) including standard survey items for youth and their caregivers; estimates of youth ASA exposures from self-reported routine activity locations combined with extensive contextual ratings and administrative data, physiological stress markers (cortisol and inflammatory), and health outcomes. The second phase will involve a supplemental intensive longitudinal data collection period taking place over a six-month period for a subsample of Phase 1 youth (N=300) selected using a novel exposure-based sampling strategy. Data collected during this supplemental phase will include an unprecedented combination of continuous high- resolution GPS tracking; ecological momentary assessments of perceived psychological and physical safety; continuously-sensed heart rate variability; and hair cortisol concentration and C-reactive protein measured at three additional time points. In addition to analyses of the novel data sources produced by the project, by drawing on data from the Adolescent Health and Development in Context Study (2014-2016) previously conducted by our study team, we will also examine recent historical changes in ASA exposures, racial disparities in safety and physiological stress, and their health consequences.

项目摘要 先前的研究已经记录了黑人和白色人之间生理压力水平的实质性差异， 确定青少年时期的个人，从发展的角度来看，这是一个特别重要的时期， 这可能会形成成年期慢性病的差异。拟议的项目旨在探讨 暴露于活动空间逆境（阿萨）的多个方面-包括区域一级的暴力， 警务，种族排他性-在促进日常（实时）的看法，无论是身体和 心理不安全感及其对解释种族生理压力差异的贡献 青春期（目标1）。我们还将考虑阿萨暴露的影响，不安全的看法， 生理压力作为物质使用和心理健康结果的预测因子（目标2）。我们将探讨 调节他人感知种族的影响--或个人认为他人感知的程度 他们的种族是黑色的公共互动-对阿萨暴露和不安全的影响，对生理压力， 健康成果。该项目将收集与目标相关的数据，这些数据来自居住在美国的种族多样化的青少年队列。 俄亥俄州哥伦布大都市区采用创新的两阶段设计：第一阶段将产生丰富的 横断面数据（N=700），包括青年及其照顾者的标准调查项目; 来自自我报告的常规活动地点的阿萨暴露与广泛的背景评级相结合， 管理数据、生理应激标记物（皮质醇和炎症）和健康结果。第二 该阶段将涉及为期六个月的补充密集纵向数据收集期 阶段1青年（N=300）的子样本使用一种新的基于抽样的策略选择。 在这一补充阶段收集的数据将包括前所未有的持续高- 全球定位系统跟踪;心理和身体安全感的生态瞬时评估; 持续感知心率变异性;毛发皮质醇浓度和C反应蛋白在 三个额外的时间点除了分析该项目产生的新数据源外， 青少年健康与发展背景研究（2014-2016）的数据， 我们的研究小组还将研究阿萨暴露的近期历史变化，安全性的种族差异， 生理压力及其健康后果。