Activity Space Adversity and Racial Disparities in Adolescent Health

青少年健康中的活动空间逆境和种族差异

• 批准号: 10754093
• 负责人: Christopher R Browning
• 金额: $ 68.62万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10754093
• 关键词: Adolescence; Adolescent; Adolescent Development; Adult; Age; Area; Black race; C-reactive protein; COVID-19 pandemic; Caregivers; Chronic Disease; Communities; Data; Data Analyses; Data Collection; Data Sources; Development; Dimensions; Disparity; Ecological momentary assessment; Exhibits; Exposure to; Hair; Health; Heterogeneity; Home; Hydrocortisone; Individual; Inflammation; Inflammatory; Intervention; Investigation; Link; Location; Measures; Mediating; Mental Health; Neighborhoods; Outcome; Patient Self-Report; Perception; Personal Satisfaction; Phase; Physiological; Police; Process; Race; Reaction; Research; Resolution; Risk; Role; Safety; Sampling; Shapes; Stress; Structural Racism; Surveys; Time; Victimization; Violence; Work; Youth; adolescent health; behavioral health; children of color; cohort; design; experience; heart rate variability; innovation; killings; metropolitan; microaggression; neglect; novel; psychologic; racial difference; racial disparity; racial diversity; racial identity; response; segregation; stress reactivity; substance use; violence exposure

PROJECT SUMMARY Prior research has documented substantial differences in levels of physiological stress among Black- and White- identifying individuals during adolescence, a period of particular importance from a developmental perspective, which may shape disparities in chronic disease in adulthood. The proposed project seeks to explore the role of exposure to multiple dimensions of activity-space adversity (ASA) – including area-level violence, elevated policing, and racial exclusivity – in contributing to everyday (real-time) perceptions of both physical and psychological unsafety and their contribution to explaining racial physiological stress disparities during adolescence (Aim 1). We will also consider the impact of ASA exposures, unsafety perceptions, and physiological stress as predictors of substance use and mental health outcomes (Aim 2). We will explore the moderating influence of other-perceived race – or the degree to which an individual believes others perceive their race to be Black in public interactions – on ASA exposure and unsafety effects on physiological stress and health outcomes. The project will collect aim-relevant data on a racially diverse cohort of adolescents residing in the Columbus, OH metropolitan area employing an innovative two-stage design: The first phase will produce rich cross-sectional data (N=700) including standard survey items for youth and their caregivers; estimates of youth ASA exposures from self-reported routine activity locations combined with extensive contextual ratings and administrative data, physiological stress markers (cortisol and inflammatory), and health outcomes. The second phase will involve a supplemental intensive longitudinal data collection period taking place over a six-month period for a subsample of Phase 1 youth (N=300) selected using a novel exposure-based sampling strategy. Data collected during this supplemental phase will include an unprecedented combination of continuous high- resolution GPS tracking; ecological momentary assessments of perceived psychological and physical safety; continuously-sensed heart rate variability; and hair cortisol concentration and C-reactive protein measured at three additional time points. In addition to analyses of the novel data sources produced by the project, by drawing on data from the Adolescent Health and Development in Context Study (2014-2016) previously conducted by our study team, we will also examine recent historical changes in ASA exposures, racial disparities in safety and physiological stress, and their health consequences.

项目摘要 先前的研究已经证明了黑人和白色之间的身体压力水平的实质性差异 在青少年期间识别个人，从发展的角度来看，一个特别重要的时期， 这可能会在成年中塑造慢性疾病的分布。拟议的项目旨在探索 暴露于活动空间广告（ASA）的多个维度 - 包括区域级暴力，提升 政策和种族排他性 - 在每天（实时）对身体和身体的看法中做出贡献 心理不安全及其对解释种族生理压力分布的贡献 青少年（AIM 1）。我们还将考虑ASA暴露，不安全的看法和 生理压力是物质使用和心理健康结果的预测因素（AIM 2）。我们将探索 调节其他感知种族的影响 - 或个人相信他人所感知的程度 他们在公众互动中成为黑人的竞赛 - 关于ASA暴露和对身体压力的不安全影响 健康结果。该项目将收集有关居住在大致多样化的青少年的相关数据 俄亥俄州哥伦布，采用创新的两阶段设计：第一阶段将产生丰富的 横断面数据（n = 700），包括针对青年及其护理人员的标准调查项目；青年的估计 ASA从自我报告的常规活动地点接触，结合了广泛的上下文评级和 行政数据，身体压力标记（皮质醇和炎症）以及健康结果。第二个 阶段将涉及在六个月内进行的补充密集纵向数据收集期 使用新型基于暴露的采样策略选择了1阶段青年的子样本（n = 300）的时期。 在此补充阶段收集的数据将包括连续高级的前所未有的组合 分辨率GPS跟踪；对感知的心理和身体安全的生态瞬时评估； 连续敏感的心率变异性；和头发皮质醇浓度和C反应蛋白 另外三个时间点。除了分析项目生产的新型数据源外， 关于上下文研究中青少年健康与发展的数据（2014- 2016年）先前由 我们的研究团队，我们还将研究ASA暴露的最新历史变化，安全性的种族分布和 生理压力及其健康后果。