Quantitative and Computational Biology Graduate Program

抽象的。要求提供支助，以延长综合性多学科培训方案， 基因组学的博士前学员，为未来的科学家提供定量和 成功的生物学研究所必需的计算工具。基因组训练计划 支持普林斯顿大学定量和计算研究生课程的学生 生物学（QCB）和其他合作部门，包括分子生物学，计算机科学， 化学，化学和生物工程，物理学，生态学和进化生物学， 由Lewis-Sigler综合基因组学研究所管理。基因组学的实习生能够 他们的实验室轮换和论文研究与任何24个附属教师在七个部门联合起来， 在定量和计算生物学的共同利益，在广泛的研究领域。 我们要求10个博士前职位（我们目前的水平），每年在拟议的赠款期间; 受训人员通常被指定领取培训补助金，为期两年。实习生做实验 和计算研究：各种模型和哺乳动物的实验功能基因组学 系统;计算项目，从大规模基因组学数据集成，分析， 人类起源和进化的可视化;单细胞基因组学和其他基因组学技术 发展;和系统生物学项目，从微生物代谢到生物物理学， 转录调控学员有个性化的，有效的培训计划，平均跨度 4.9对于那些获得博士学位的人来说，在过去的十年里。正规培训包括以下课程： 基因组学和基因组分析，系列研讨会，期刊俱乐部/演示课程，负责 进行适合实验和计算研究的研究培训，以及其他 以研究所为中心的多学科活动。学员有机会在一个 普林斯顿大学为本科生提供的创新的多学科入门课程。最后，学员和 符合条件的教师参加一些旨在招募和教授个人的活动， 代表性不足的少数群体成员。

Abstract. Support is requested for the renewal of an integrated, multidisciplinary training program for pre-doctoral trainees in genomics, with the goal of providing future scientists with the quantitative and computational tools necessary for successful biological research. The genome-training program supports students in Princeton University’s Graduate Program in Quantitative and Computational Biology (QCB) and other partner departments, including Molecular Biology, Computer Science, Chemistry, Chemical and Biological Engineering, Physics, and Ecology and Evolutionary Biology and is administered by the Lewis-Sigler Institute for Integrative Genomics. Genomics trainees are able to do their lab rotations and thesis research with any of 24 affiliated faculty in seven departments united by common interests in quantitative and computational biology, across a wide range of research areas. We request 10 pre-doctoral positions (our current level) each year during the proposed grant period; trainees typically are appointed to the training grant for a total of two years. Trainees do experimental and computational research in: experimental functional genomics in a variety of model and mammalian systems; computational projects ranging from large-scale genomics data integration, analysis, and visualization to human origins and evolution; single-cell genomics and other genomics technology development; and systems biology projects ranging from microbial metabolism to the biophysics of transcriptional regulation. Trainees have individualized, efficient training plans, which span on average 4.9 years, for those who received their Ph.D. in the last ten years. Formal training includes courses in genomics and genomic analysis, a seminar series, a journal club / presentation course, responsible conduct in research training appropriate for both experimental and computational research, and other multidisciplinary activities centered in the Institute. Trainees have the opportunity to teach in an innovative multidisciplinary introductory program for undergraduates at Princeton. Finally, trainees and eligible faculty participate in a number of activities designed to recruit and teach individuals who are members of under-represented minority groups.