2-Generation Interventions to Improve Cardiovascular Health in Indiana and Illinois Through Home Visiting (2-NOURISH)

通过家访改善印第安纳州和伊利诺伊州心血管健康的第二代干预措施 (2-NOURISH)

基本信息

  • 批准号:
    10622594
  • 负责人:
  • 金额:
    $ 81.48万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-05-16 至 2024-06-30
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY This application proposing the 2-GeneratioN Interventions to ImprOve CardiovascUlaR Health in Indiana and IllinoiS Through Home Visiting (2-NOURISH) is in response to the RFA “Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite Clinical Center (RFA-HL-22-007)”. Given growing rates of maternal morbidity and mortality, interventions to optimize maternal cardiovascular health (CVH) are urgently needed. Poor maternal CVH is also associated with poor offspring CVH. As a result, the perinatal period is an opportune time to intervene, but evidence-based interventions are limited. Home visiting (HV) programs serve as an ideal setting to conduct intervention research aimed at improving maternal and child CVH as they already serve an at-risk population across the United States with a high prevalence of poor CVH. The proposed Clinical Center, 2-NOURISH, led by Northwestern, in partnership with two evidence-based HV models (Healthy Families America [HFA] and Parents as Teachers [PAT]), and an evidence-based virtual platform for lifestyle intervention, Weight Watchers International (WW), is uniquely qualified to participate in all aspects of the ENRICH Network and to substantially enhance the Network’s goals. In our application, we demonstrate key prior experiences, which include: (1) long-standing collaborations with HV models, including MPI Tandon’s evidence-based perinatal depression and stress management intervention (Mothers and Babies); (2) significant expertise in the development and assessment of maternal and child CVH, particularly during the perinatal period; and (3) extensive experience with recruitment and retention of diverse populations for behavior interventions. During the UG3 phase (Years 1-2), we will work collaboratively within the ENRICH Network to develop a common study protocol, adapt the intervention content, and conduct pilot tests. During the UH3 phase (Years 3-7), we will recruit 600 mother-child dyads in partnership with 40 HV programs in Illinois and Indiana within the proposed study timeline to achieve the ENRICH Network Goal of 3000 total dyads to examine the effectiveness of an implementation-ready, CVH-focused, evidence-based intervention. We carefully considered potential study designs and propose a Hybrid Effectiveness-Implementation Type 1 trial with a cluster randomized design that would randomize at the home visitor-level. Additionally, given the potential maternal and offspring benefits of intervention during pregnancy, we propose prenatal recruitment. Our proposed intervention also includes innovative prenatal (promotion of stress management techniques, home visitor patient navigation) and postpartum (intensive lifestyle intervention with a virtual delivery platform, peer support) components. Our Clinical Center is additionally committed to developing the skills of Early Stage Investigators related to clinical trial design and the skills of home visitors related to the construct of CVH, its components, and the common study protocol. 2-NOURISH is ideally suited to serve as a Clinical Center and contribute to the Network’s long-term mission to equitably improve maternal and early childhood CVH.
项目总结

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Matthew M Davis其他文献

Risk factors for death during newborn and post-newborn hospitalizations among preterm infants
早产儿新生儿和新生儿住院期间死亡的危险因素
  • DOI:
    10.1038/s41372-022-01363-z
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    N. Matoba;Soyang Kwon;J. Collins;Matthew M Davis
  • 通讯作者:
    Matthew M Davis
Being specific about being special: defining children's conditions and special health care needs.
明确特殊性:定义儿童的状况和特殊的医疗保健需求。
Reimbursement for Prevnar: a modern-day version of Hercules and the Hydra.
Prevnar 的报销:现代版的大力神和九头蛇。
  • DOI:
  • 发表时间:
    2002
  • 期刊:
  • 影响因子:
    8
  • 作者:
    G. Freed;Matthew M Davis;M. Andreae;Susan Bass;H. Weinblatt
  • 通讯作者:
    H. Weinblatt
Correction to: Hospital discharges for fever and neutropenia in pediatric cancer patients: United States, 2009
更正:儿童癌症患者因发烧和中性粒细胞减少症出院:美国,2009 年
  • DOI:
  • 发表时间:
    2017
  • 期刊:
  • 影响因子:
    3.8
  • 作者:
    Emily L. Mueller;K. Walkovich;R. Mody;A. Gebremariam;Matthew M Davis
  • 通讯作者:
    Matthew M Davis
Increasing Incidence and Geographic Distribution of Neonatal Abstinence Syndrome: United States 2009-2012
新生儿戒断综合症发病率上升及地理分布:美国 2009-2012 年
  • DOI:
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    S. Patrick;Matthew M Davis;C. U. Lehman;W. Cooper
  • 通讯作者:
    W. Cooper

Matthew M Davis的其他文献

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{{ truncateString('Matthew M Davis', 18)}}的其他基金

2-Generation Interventions to Improve Cardiovascular Health in Indiana and Illinois Through Home Visiting (2-NOURISH)
通过家访改善印第安纳州和伊利诺伊州心血管健康的第二代干预措施 (2-NOURISH)
  • 批准号:
    10427796
  • 财政年份:
    2022
  • 资助金额:
    $ 81.48万
  • 项目类别:
Using MEPS Data to Inform Public-Plan Consumerism
使用 MEPS 数据为公共计划消费主义提供信息
  • 批准号:
    7322652
  • 财政年份:
    2007
  • 资助金额:
    $ 81.48万
  • 项目类别:
Understanding & Estimating Costs of Vaccine Development,Production and Pricing
理解
  • 批准号:
    7282371
  • 财政年份:
    2006
  • 资助金额:
    $ 81.48万
  • 项目类别:
Understanding & Estimating Costs of Vaccine Development,Production and Pricing
理解
  • 批准号:
    7229176
  • 财政年份:
    2006
  • 资助金额:
    $ 81.48万
  • 项目类别:
Understanding & Estimating Costs of Vaccine Development,Production and Pricing
理解
  • 批准号:
    7684335
  • 财政年份:
    2006
  • 资助金额:
    $ 81.48万
  • 项目类别:
Pediatric Health Services Research Training
儿科健康服务研究培训
  • 批准号:
    8069249
  • 财政年份:
    2000
  • 资助金额:
    $ 81.48万
  • 项目类别:
Pediatric Health Services Research Training
儿科健康服务研究培训
  • 批准号:
    8263057
  • 财政年份:
    2000
  • 资助金额:
    $ 81.48万
  • 项目类别:
Pediatric Health Services Research Training
儿科健康服务研究培训
  • 批准号:
    8658117
  • 财政年份:
    2000
  • 资助金额:
    $ 81.48万
  • 项目类别:
Pediatric Health Services Research Training
儿科健康服务研究培训
  • 批准号:
    8461119
  • 财政年份:
    2000
  • 资助金额:
    $ 81.48万
  • 项目类别:

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