Administrative and Field Coordination Core

项目摘要/摘要(行政和外地协调核心) 为了最大限度地提高心血管疾病的精确度和影响 CARRS队列中的病理生理途径(Precision-CARRS)，管理和领域 协调(亚足联)核心将提供科学和业务治理(目标1)；实地和实验室监督 (目标2)；和通信服务(目标3)，以支持这一多地点方案项目赠款(PPG)。亚足联 CORE将建立在埃默里大学和埃默里大学之间长达十年的富有成效的合作和无缝协调的基础上 其在印度的合作机构进行跨国科学发现。核心基地将设在埃默里和 慢性病控制中心(CCDC)。亚足联核心-埃默里将利用现有的行政管理 基础设施、多名首席调查员、项目负责人以及数据管理和分析核心 领导团队。亚足联的核心-埃默里将负责监管和沟通职能。亚足联核心- CCDC由CVD表型鉴定核心、德里和金奈现场引线以及现场和实验室组成 领袖们。AFC Core-CCDC将监督现场数据收集和实验室质量监督过程， 凭借十年的经验、当地知识、与社区的伙伴关系以及与当地居民的联系 和国家政府。亚足联核心将成立指导委员会，促进凝聚力和联动性 三个核心和四个项目。为了提供有效的治理(目标1)，亚足联核心将容纳一个 执行委员会由有良好合作记录的知名科学家组成，他们共同 制定了PPG的愿景和组织结构。核心招聘了一名杰出的内部顾问 小组，并制定了一个外部咨询小组的计划，以获得战略指导并提高对 精度-CARRS。亚足联核心将加强以前制定的透明行政政策和 进程，包括定期报告机制，以确保实现PPG目标。政策和流程 旨在提高PPG的效率和凝聚力。支持质量保证和控制 对于所有数据收集、处理和实验室方法(目标2)，AFC核心包含现场操作和 实验室委员会，由具有专业知识和管理经验的调查人员组成 卡尔·科霍特。该小组将更新和实施操作、培训、监测和 报告包括将在未来五年的PPG收集的精确措施。为了促进 有效的内部沟通、传播、扩大协作和影响(目标3)，亚足联核心将 扩大现有的出版、演示和辅助研究委员会。亚足联核心也将建立 互动、跟踪和报告的新渠道。通过其结构、活动和人员的组合， AFC Core准备支持这个PPG的交叉目标、科学影响和可见性。

PROJECT SUMMARY / ABSTRACT (Administrative and Field Coordination Core) To maximize the cohesiveness and impacts of the Precision Cardiovascular Disease Phenotyping and Pathophysiological Pathways in the CARRS cohort (Precision-CARRS), the Administrative and Field Coordination (AFC) Core will provide scientific and operational governance (Aim 1); field and laboratory oversight (Aim 2); and communication services (Aim 3) to support this multi-site Program Project Grant (PPG). The AFC Core will build on ten years of productive collaboration and seamless coordination between Emory University and its partner institutions in India to conduct cross-national scientific discovery. The Core will be based at Emory and the Centre for Chronic Disease Control (CCDC). The AFC Core-Emory will leverage existing administrative infrastructure, the multiple Principal Investigators, Project Leads, and the Data Management and Analysis Core leadership team. The AFC Core-Emory will oversee governance and communication functions. The AFC Core- CCDC is comprised of the CVD Phenotyping Core, Delhi and Chennai Site Leads, and field and laboratory leaders. The AFC Core-CCDC will oversee field data collection and laboratory quality oversight processes, drawing on ten years of experience, local knowledge, partnerships with communities, and connections with local and national government. The AFC Core will establish a Steering Committee to facilitate cohesion and linkage across the three Cores and four Projects. To provide effective governance (Aim 1), the AFC Core will house an Executive Committee comprised of established scientists with a strong track-record of collaboration who co- developed the PPG’s vision and organizational structure. The Core has recruited an illustrious Internal Advisory Group, and laid out plans for an External Advisory Group to obtain strategic guidance and raise the visibility of Precision-CARRS. The AFC Core will augment previously-developed transparent administrative policies and processes, including regular reporting mechanisms to ensure PPG goals are being met. Policies and processes are intended to stimulate efficiency and cohesiveness across the PPG. To support quality assurance and control for all data collection, handling, and laboratory methods (Aim 2), the AFC Core houses the Field Operations and Laboratory Committee which is comprised of investigators with expertise and experience in managing the CARRS Cohort. This group will update and operationalize manuals of operation, training, monitoring, and reporting to include precision measures that will be collected in the coming five years of the PPG. To promote effective internal communication, dissemination, and grow collaborations and impact (Aim 3), the AFC Core will expand the existing Publication, Presentation, and Ancillary Studies Committee. The AFC Core will also establish new channels of interaction, tracking, and reporting. Through its mix of structures, activities and personnel, the AFC Core is poised to support this PPG’s cross-cutting goals, scientific impacts, and visibility.