Administrative and Field Coordination Core

项目概要/摘要（行政和外地协调核心） 为了最大限度地提高精确心血管疾病表型分析的凝聚力和影响力， CARRS队列（Precision-CARRS）中的病理生理学途径，管理和现场 协调（AFC）核心将提供科学和业务管理（目标1）;现场和实验室监督 (Aim 2）;和通信服务（目标3），以支持这一多地点计划项目补助金（PPG）。亚足联 核心将建立在埃默里大学和 它与印度的合作机构合作，进行跨国科学发现。核心将设在埃默里大学， 慢性病控制中心（CCDC）。AFC核心-埃默里将利用现有的行政 基础设施、多个主要研究者、项目负责人以及数据管理和分析核心 领导团队。AFC核心埃默里将监督治理和沟通职能。AFC核心- CCDC由CVD表型核心、德里和钦奈研究中心负责人以及现场和实验室组成 领导人的人选信号AFC核心-CCDC将监督现场数据收集和实验室质量监督过程， 利用十年的经验，当地知识，与社区的伙伴关系，以及与当地 和国家政府。亚足联核心将成立一个指导委员会，以促进凝聚力和联系 三个核心和四个项目。为了提供有效的治理（目标1），AFC核心将容纳一个 执行委员会由具有良好合作记录的知名科学家组成， 制定了PPG的愿景和组织结构。核心招募了一位杰出的内部顾问 小组，并制定了外部咨询小组的计划，以获得战略指导和提高 精密-CARRS。AFC核心将增强先前制定的透明行政政策， （c）确保实现项目编制小组目标的定期报告机制。政策和进程 旨在提高PPG的效率和凝聚力。支持质量保证和控制 对于所有数据收集、处理和实验室方法（目标2），AFC核心包含现场操作， 实验室委员会由具有管理 CARRS队列。该小组将更新业务、培训、监测和培训手册， 报告包括将在未来五年的PPG中收集的精确测量。促进 有效的内部沟通，传播，并扩大合作和影响（目标3），AFC核心将 扩大现有的出版，演示和辅助研究委员会。AFC核心还将建立 互动、跟踪和报告的新渠道。通过其结构、活动和人员的组合， AFC核心准备支持这个PPG的跨领域目标，科学影响和知名度。

PROJECT SUMMARY / ABSTRACT (Administrative and Field Coordination Core) To maximize the cohesiveness and impacts of the Precision Cardiovascular Disease Phenotyping and Pathophysiological Pathways in the CARRS cohort (Precision-CARRS), the Administrative and Field Coordination (AFC) Core will provide scientific and operational governance (Aim 1); field and laboratory oversight (Aim 2); and communication services (Aim 3) to support this multi-site Program Project Grant (PPG). The AFC Core will build on ten years of productive collaboration and seamless coordination between Emory University and its partner institutions in India to conduct cross-national scientific discovery. The Core will be based at Emory and the Centre for Chronic Disease Control (CCDC). The AFC Core-Emory will leverage existing administrative infrastructure, the multiple Principal Investigators, Project Leads, and the Data Management and Analysis Core leadership team. The AFC Core-Emory will oversee governance and communication functions. The AFC Core- CCDC is comprised of the CVD Phenotyping Core, Delhi and Chennai Site Leads, and field and laboratory leaders. The AFC Core-CCDC will oversee field data collection and laboratory quality oversight processes, drawing on ten years of experience, local knowledge, partnerships with communities, and connections with local and national government. The AFC Core will establish a Steering Committee to facilitate cohesion and linkage across the three Cores and four Projects. To provide effective governance (Aim 1), the AFC Core will house an Executive Committee comprised of established scientists with a strong track-record of collaboration who co- developed the PPG’s vision and organizational structure. The Core has recruited an illustrious Internal Advisory Group, and laid out plans for an External Advisory Group to obtain strategic guidance and raise the visibility of Precision-CARRS. The AFC Core will augment previously-developed transparent administrative policies and processes, including regular reporting mechanisms to ensure PPG goals are being met. Policies and processes are intended to stimulate efficiency and cohesiveness across the PPG. To support quality assurance and control for all data collection, handling, and laboratory methods (Aim 2), the AFC Core houses the Field Operations and Laboratory Committee which is comprised of investigators with expertise and experience in managing the CARRS Cohort. This group will update and operationalize manuals of operation, training, monitoring, and reporting to include precision measures that will be collected in the coming five years of the PPG. To promote effective internal communication, dissemination, and grow collaborations and impact (Aim 3), the AFC Core will expand the existing Publication, Presentation, and Ancillary Studies Committee. The AFC Core will also establish new channels of interaction, tracking, and reporting. Through its mix of structures, activities and personnel, the AFC Core is poised to support this PPG’s cross-cutting goals, scientific impacts, and visibility.