Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I-TEST BP/Stroke)

扩展受音乐启发的血压和中风预防策略的创新工具（I-TEST BP/中风）

• 批准号: 10937709
• 负责人: OLIVER CHUKWUJEKWU EZECHI
• 金额: $ 71.66万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-29 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10937709
• 关键词: Innovative; Tools; Expand; Music; Inspired

Expanding evidence-based blood pressure/stroke prevention interventions for youth and their older adult caregivers (parents, grandparents, etc.) is critical to achieving the World Health Organization (WHO) and Nigerian goals for reducing the hypertension and stroke burden. Innovative strategies that engage local communities, link younger and older generations, and decrease health disparities are urgently needed. Music is a positive social determinant of health that is inclusive and can allow people to achieve healthy outcomes. It is also a non-invasive, safe, inexpensive, evidence-based implementation strategy, that can be used to engage youth in intervention design and evaluation tailored to their specific needs and those of their older adult caregivers. The effectiveness of music as an implementation strategy has been documented in various randomized control trials, including blood pressure and stroke prevention interventions. Nigeria also has a rich music culture that can be leveraged to increase uptake of evidence-based BP/stroke interventions. We propose “Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I- TEST BP/Stroke)” to accelerate behavioral BP/stroke campaigns in Nigeria inspired by music. I-TEST- BP/stroke will use participatory crowdsourcing methods to drive BP/stroke prevention among youth/caregiver dyads in Nigeria. Crowdsourcing open calls will allow us to identify locally relevant music-inspired campaigns to increase uptake of BP/stroke prevention. Then, apprenticeships with music and public-health professionals will build capacity for implementing these campaigns using common music elements (i.e., rhythms, beats, lyrics) known to impact cardiovascular health. Our preliminary data from Nigeria demonstrate that youth can develop effective public health interventions using these participatory methods. Our partnership with the Nigerian Institute of Medical Research provides extensive experience in implementation research, participatory methods, and pragmatic trials. Building on this strong foundation, our multi-disciplinary research team proposes a hybrid type II implementation trial with these specific aims: (1) to develop a new, combined, music- inspired BP/stroke campaigns for youth/caregiver dyads using crowdsourcing open calls and apprenticeships; (2) to determine whether the final music-inspired campaign increases uptake of BP/stroke prevention interventions among youth and their caregivers using a stepped-wedge, pragmatic randomized controlled trial (RCT) in 30 geographic areas; (3) to use mixed-methods approach to explore multi-level factors that influence the uptake of the music-inspired strategy. Our primary outcomes will be the uptake of strategy and BP/stroke preventive measures defined here as maintenance of normal BP rates for youth, systolic blood pressure reduction for caregivers, and increase in stroke preparedness knowledge. Secondary outcomes are reach, fidelity, acceptability, and sustainment. Our study is responsive to the strategic priorities of the United States National Institutes of Health, Sound Health, the WHO, the Nigerian Ministry of Health and PAR-22-132.

扩大针对青年及其老年人的基于证据的血压/中风预防干预措施 照顾者（父母，祖父母等）对于实现世界卫生组织（WHO）和 尼日利亚减少高血压和中风的目标。吸引本地的创新策略 迫切需要社区，与年轻和年长的一代联系，并迫切需要减少健康差异。音乐 是一种积极的社会决定者，具有包容性，可以允许人们取得健康的结果。它 也是一种无创，安全，廉价，基于证据的实施策略，可用于参与 干预设计和评估的青年针对其特定需求和老年人的需求量 照顾者。音乐作为实施策略的有效性已在各种 随机对照试验，包括血压和预防中风干预措施。尼日利亚也有富人 可以利用的音乐文化可以增加循证基于证据的BP/中风干预措施。我们 提案“扩大音乐启发性血压和中风预防策略（I-）的创新工具（I-） 测试BP/中风）”以音乐启发的尼日利亚加速行为BP/中风运动。I-TEST- BP/Stroke将使用参与攀岩方法来推动青年/看护者的预防BP/中风 尼日利亚的二元。众包公开电话将使我们能够确定与当地相关的音乐启发的广告系列 增加预防BP/中风的摄取。然后，与音乐和公共卫生专业人士的学徒制 将使用常见的音乐元素（即节奏，节拍，， 歌词）已知会影响心血管健康。我们来自尼日利亚的初步数据表明，青年可以 使用这些参与方法制定有效的公共卫生干预措施。我们与 尼日利亚医学研究所在实施研究，参与方面提供丰富的经验 方法和务实的试验。我们的多学科研究团队以这个强大的基础为基础 提案采用这些特定目的的II型混合实施试验：（1）开发一种新的，合并的音乐 - 使用众包的公开电话和学徒制定了针对青年/照顾者二元组的BP/中风运动； （2）确定最终音乐启发的广告系列是否增加了BP/中风预防的吸收 使用阶梯式北向，务实的随机对照试验进行干预措施 （RCT）在30个地理区域； （3）使用混合方法方法来探索影响的多层次因素 音乐启发的策略的吸收。我们的主要结果将是策略和BP/中风的吸收 这里定义为预防措施是维持青年正常BP率，收缩压 减少护理人员，并增加中风准备知识。次要结果是触及的， 忠诚，可接受性和维持。我们的研究对美国的战略重点有回应 美国国立卫生研究院，卫生研究院，尼日利亚卫生部和22-132年。