Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I-TEST BP/Stroke)

扩展受音乐启发的血压和中风预防策略的创新工具（I-TEST BP/中风）

• 批准号: 10937709
• 负责人: OLIVER CHUKWUJEKWU EZECHI
• 金额: $ 71.66万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-29 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10937709
• 关键词: Innovative; Tools; Expand; Music; Inspired

Expanding evidence-based blood pressure/stroke prevention interventions for youth and their older adult caregivers (parents, grandparents, etc.) is critical to achieving the World Health Organization (WHO) and Nigerian goals for reducing the hypertension and stroke burden. Innovative strategies that engage local communities, link younger and older generations, and decrease health disparities are urgently needed. Music is a positive social determinant of health that is inclusive and can allow people to achieve healthy outcomes. It is also a non-invasive, safe, inexpensive, evidence-based implementation strategy, that can be used to engage youth in intervention design and evaluation tailored to their specific needs and those of their older adult caregivers. The effectiveness of music as an implementation strategy has been documented in various randomized control trials, including blood pressure and stroke prevention interventions. Nigeria also has a rich music culture that can be leveraged to increase uptake of evidence-based BP/stroke interventions. We propose “Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I- TEST BP/Stroke)” to accelerate behavioral BP/stroke campaigns in Nigeria inspired by music. I-TEST- BP/stroke will use participatory crowdsourcing methods to drive BP/stroke prevention among youth/caregiver dyads in Nigeria. Crowdsourcing open calls will allow us to identify locally relevant music-inspired campaigns to increase uptake of BP/stroke prevention. Then, apprenticeships with music and public-health professionals will build capacity for implementing these campaigns using common music elements (i.e., rhythms, beats, lyrics) known to impact cardiovascular health. Our preliminary data from Nigeria demonstrate that youth can develop effective public health interventions using these participatory methods. Our partnership with the Nigerian Institute of Medical Research provides extensive experience in implementation research, participatory methods, and pragmatic trials. Building on this strong foundation, our multi-disciplinary research team proposes a hybrid type II implementation trial with these specific aims: (1) to develop a new, combined, music- inspired BP/stroke campaigns for youth/caregiver dyads using crowdsourcing open calls and apprenticeships; (2) to determine whether the final music-inspired campaign increases uptake of BP/stroke prevention interventions among youth and their caregivers using a stepped-wedge, pragmatic randomized controlled trial (RCT) in 30 geographic areas; (3) to use mixed-methods approach to explore multi-level factors that influence the uptake of the music-inspired strategy. Our primary outcomes will be the uptake of strategy and BP/stroke preventive measures defined here as maintenance of normal BP rates for youth, systolic blood pressure reduction for caregivers, and increase in stroke preparedness knowledge. Secondary outcomes are reach, fidelity, acceptability, and sustainment. Our study is responsive to the strategic priorities of the United States National Institutes of Health, Sound Health, the WHO, the Nigerian Ministry of Health and PAR-22-132.

扩大青年及其老年人的循证血压/中风预防干预措施 照顾者（父母、祖父母等）对实现世界卫生组织（WHO）和 尼日利亚降低高血压和中风负担的目标。使当地参与的创新战略 因此，迫切需要建立社区、联系年轻一代和老年一代以及减少健康差距的机制。音乐 是健康的一个积极的社会决定因素，具有包容性，可以使人们实现健康的结果。它 也是一种非侵入性，安全，廉价，循证的实施策略，可用于参与 青年参与针对他们和老年人具体需要的干预措施设计和评价 照顾者音乐作为一种实施策略的有效性已被记录在各种文件中。 随机对照试验，包括血压和中风预防干预。尼日利亚也有一个富有的 音乐文化，可以利用，以增加吸收循证BP/中风干预措施。我们 提出“创新工具，以扩大音乐启发的血压和中风预防策略（I- 测试血压/中风）”，以加快行为BP/中风运动在尼日利亚的灵感来自音乐。I-TEST- BP/中风将使用参与式众包方法在青少年/护理人员中推动BP/中风预防 在尼日利亚的二分体。众包公开电话将使我们能够确定当地相关的音乐灵感的运动 以增加BP/中风预防的摄取。然后，与音乐和公共卫生专业人员的学徒 将利用共同的音乐元素（即，节奏，节拍， 歌词）已知影响心血管健康。我们从尼日利亚获得的初步数据表明， 利用这些参与性方法制定有效的公共卫生干预措施。我们与 尼日利亚医学研究所在实施研究、参与性研究和 方法和务实的尝试。在这个坚实的基础上，我们的多学科研究团队 提出了一个混合型II实施试验，这些具体目标：（1）开发一个新的，结合，音乐- 利用众包公开电话和学徒制，为青年/护理人员二人组开展有启发性的BP/中风运动; (2)以确定最终的音乐启发运动是否增加了BP/中风预防的摄取 在青少年及其照顾者中进行干预：一项采用阶梯楔形、实用的随机对照试验 (RCT)（3）采用混合方法探讨多层次影响因素 对音乐启发策略的理解我们的主要结果将是策略的采用和BP/卒中 这里定义的预防措施是维持年轻人的正常血压率， 减少护理人员的死亡率，增加卒中准备知识。次要结果是达到， 忠诚度、可接受性和可持续性。我们的研究响应了美国的战略重点 国立卫生研究院，健全的健康，世界卫生组织，尼日利亚卫生部和PAR-22-132。