Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I-TEST BP/Stroke)

扩大针对青年及其老年人的循证血压/中风预防干预措施 照顾者(父母、祖父母等)对实现世界卫生组织(世卫组织)和 尼日利亚降低高血压和中风负担的目标。与当地接洽的创新战略 迫切需要在社区建立联系，将年轻一代和年长一代联系起来，缩小健康差距。乐谱 是健康的一个积极的社会决定因素，具有包容性，能够使人们实现健康的结果。它 也是一种非侵入性、安全、廉价、基于证据的实施战略，可用于 青少年的干预设计和评估是根据他们和老年人的特定需求量身定做的 照顾者。音乐作为一种实施战略的有效性已在各种不同的文件中得到记录 随机对照试验，包括血压和中风预防干预。尼日利亚也有一个富有的 音乐文化，可以被用来增加循证BP/中风干预的接受。我们 建议“创新工具以扩展音乐启发的血压和中风预防策略(I- 测试血压/中风)“，以加快尼日利亚在音乐启发下的行为血压/中风运动。I-测试- BP/中风将使用参与性众包方法在青年/照顾者中推动BP/中风预防 尼日利亚的双胞胎。众包开放呼叫将使我们能够识别受当地音乐启发的活动 以增加对BP/中风预防的摄取。然后，与音乐和公共卫生专业人员一起当学徒 将利用共同的音乐元素(即节奏、节拍、 歌词)已知会影响心血管健康。我们来自尼日利亚的初步数据表明，年轻人可以 利用这些参与性方法制定有效的公共卫生干预措施。我们的合作伙伴关系 尼日利亚医学研究所在实施研究、参与性研究方面提供丰富的经验 方法和实践性试验。在这个坚实的基础上，我们的多学科研究团队 提出了一项混合类型II实施试验，具体目标如下：(1)开发一种新的、组合的MUSIC- 通过众包开放电话和学徒制，为青年/照顾者二人组发起了受启发的BP/中风运动； (2)确定最终以音乐为灵感的运动是否增加了对BP/中风预防的接受 采用阶梯式楔形务实随机对照试验对青少年及其照顾者进行干预 (3)采用混合方法探索影响因素的多层次 对音乐启发策略的理解。我们的主要成果将是采用战略和BP/卒中 这里定义的预防措施是维持青年正常的血压、收缩压 减少护理人员，增加中风预防知识。次要结果是达到， 忠诚度、可接受性和支持性。我们的研究是对美国的战略重点的回应 国家卫生、健康、世界卫生组织、尼日利亚卫生部和PAR-22-132。

Expanding evidence-based blood pressure/stroke prevention interventions for youth and their older adult caregivers (parents, grandparents, etc.) is critical to achieving the World Health Organization (WHO) and Nigerian goals for reducing the hypertension and stroke burden. Innovative strategies that engage local communities, link younger and older generations, and decrease health disparities are urgently needed. Music is a positive social determinant of health that is inclusive and can allow people to achieve healthy outcomes. It is also a non-invasive, safe, inexpensive, evidence-based implementation strategy, that can be used to engage youth in intervention design and evaluation tailored to their specific needs and those of their older adult caregivers. The effectiveness of music as an implementation strategy has been documented in various randomized control trials, including blood pressure and stroke prevention interventions. Nigeria also has a rich music culture that can be leveraged to increase uptake of evidence-based BP/stroke interventions. We propose “Innovative Tools to Expand Music-Inspired Strategies for Blood Pressure and Stroke Prevention (I- TEST BP/Stroke)” to accelerate behavioral BP/stroke campaigns in Nigeria inspired by music. I-TEST- BP/stroke will use participatory crowdsourcing methods to drive BP/stroke prevention among youth/caregiver dyads in Nigeria. Crowdsourcing open calls will allow us to identify locally relevant music-inspired campaigns to increase uptake of BP/stroke prevention. Then, apprenticeships with music and public-health professionals will build capacity for implementing these campaigns using common music elements (i.e., rhythms, beats, lyrics) known to impact cardiovascular health. Our preliminary data from Nigeria demonstrate that youth can develop effective public health interventions using these participatory methods. Our partnership with the Nigerian Institute of Medical Research provides extensive experience in implementation research, participatory methods, and pragmatic trials. Building on this strong foundation, our multi-disciplinary research team proposes a hybrid type II implementation trial with these specific aims: (1) to develop a new, combined, music- inspired BP/stroke campaigns for youth/caregiver dyads using crowdsourcing open calls and apprenticeships; (2) to determine whether the final music-inspired campaign increases uptake of BP/stroke prevention interventions among youth and their caregivers using a stepped-wedge, pragmatic randomized controlled trial (RCT) in 30 geographic areas; (3) to use mixed-methods approach to explore multi-level factors that influence the uptake of the music-inspired strategy. Our primary outcomes will be the uptake of strategy and BP/stroke preventive measures defined here as maintenance of normal BP rates for youth, systolic blood pressure reduction for caregivers, and increase in stroke preparedness knowledge. Secondary outcomes are reach, fidelity, acceptability, and sustainment. Our study is responsive to the strategic priorities of the United States National Institutes of Health, Sound Health, the WHO, the Nigerian Ministry of Health and PAR-22-132.