Integration of Hypertension Management into HIV Care in Nigeria: A Task Strengthening Strategy

摘要 “将高血压管理融入尼日利亚的艾滋病毒护理：加强战略的任务”(TASSH NIMR)Parent研究是一项正在进行的临床有效性实施试验，旨在评估 整合艾滋病毒高血压控制(TASSH)任务强化战略的实施战略 拉各斯州的诊所(R01HL147811)。为了回应NOT-OD-21-020，我们建议此管理 增刊《通过任务建立艾滋病-高血压综合伦理学学习协作组》 尼日利亚拉各斯州加强高血压控制战略“(E-LINC TASSH)。E-Linc TASSH将 利用TASSH NIMR指导委员会组成道德学习协作(ELC)，该委员会将 确定、分析和描述实施实践促进导向任务的伦理考虑因素- 在整个初级卫生保健中心加强高血压和艾滋病毒夫妇治疗的方法 拉各斯州立大学。此外，E-Linc TASSH将开发一种道德知情的战略，以扩大、传播和 继续在拉各斯州的艾滋病毒诊所开展TASSH NIMR干预。为了更好地欣赏 实施研究提供信息的学习协作，以促进艾滋病毒的生物伦理考虑- 高血压综合，本补充还将评估使用以伦理为重点的协作学习。 扩展到这一生物伦理学研究领域将使我们能够全面理解和了解背景 实施这种治疗和管理模式的伦理思考。这项生命伦理学研究将 使我们能够制定战略，以管理和解决在实施过程中出现的道德挑战 TASSH NIMR战略的研究和放大。TASSH NIMR目前处于实施前或 规划阶段，并将及时开始招聘，以便进行拟议的研究，以增强干预措施的影响 并告知下一步在拉各斯州内扩大、传播和维持干预的步骤 初级卫生保健网络。除了从事拟议的生物伦理学研究外，E-Linc TASSH还将建立 通过专家促成的讨论和活动提高ELC成员的研究伦理和生物伦理能力 参与制定调查、与利益相关方接触、解释调查结果以及整合这一新的 将知识转化为实际的战略。 根据NOT-OD-21-020中的说明，本补编专门针对生物伦理研究和能力建设。

Abstract The “Integration of Hypertension Management into HIV Care in Nigeria: A Task Strengthening Strategy” (TASSH NIMR) parent study is an ongoing clinical effectiveness implementation trial that evaluates the effectiveness of an implementation strategy to integrate a task-strengthening strategy for hypertension control (TASSH) in HIV clinics in Lagos State (R01HL147811). In response to NOT-OD-21-020, we propose this administrative supplement, “Establishing an Ethics Learning Collaborative for HIV-Hypertension Integration through a TAsk Strengthening Strategy for Hypertension Control in Lagos State, Nigeria” (E-LinC TASSH). E-LinC TASSH will leverage the TASSH NIMR Steering Committee to form an Ethics Learning Collaborative (ELC), which will identify, analyze, and characterize ethical considerations for implementing a practice facilitation–guided task- strengthening approach to couple hypertension and HIV treatment within primary health care centers throughout Lagos State. Additionally, E-LinC TASSH will develop an ethics-informed strategy for scaling up, spreading, and sustaining the TASSH NIMR intervention in HIV clinics throughout Lagos State. To better appreciate an implementation research informed learning collaboratives to advance bioethical considerations in HIV- hypertension integration, this supplement will also evaluate use of an ethics focused learning collaborative. Expansion into this area of bioethics research will allow us to comprehensively understand and contextualize ethical considerations of implementing this treatment and management model. This bioethics research will enable us to develop strategies for managing and solving ethical challenges arising in our implementation research and scale-up of the TASSH NIMR strategy. TASSH NIMR is currently in the pre-implementation or planning phase and will begin recruitment in time for the proposed research to enhance the intervention's impact and to inform the next steps for scaling up, spreading, and sustaining the intervention within the Lagos State primary healthcare network. In addition to engaging in the proposed bioethics research, E-LinC TASSH will build research ethics and bioethics capacity among ELC members through expert-facilitated discussions and activities involved in developing the survey, engaging stakeholders, interpreting findings, and integrating this new knowledge into practical strategies. Per instructions in NOT-OD-21-020, this supplement is specific to bioethics research and capacity building.