Clinical and Translational Science Institute at Childrens National-Mentored Career Development Core

儿童国家指导职业发展核心的临床和转化科学研究所

• 批准号: 9308042
• 负责人: NAOMI L LUBAN
• 金额: $ 36.4万
• 依托单位: CHILDREN'S RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9308042
• 关键词: Acceleration; Adult; Affinity; Applications Grants; Area; Bioinformatics; Biological; Biomedical Engineering; Chemicals; Child; Child health care; Childhood; Clinic; Clinical Research; Clinical Sciences; Clinical Trials; Competence; Data; Development Plans; Disease; Distance Education; E-learning; Education; Educational Curriculum; Ensure; Epidemiology; Evaluation; Funding; Genomics; Grant; Health Policy; Health Services; Health Services Research; Health system; Industry; Institutes; Institution; Laboratories; Lead; Leadership; Learning; Measures; Medical; Mentors; Mentorship; Methodology; Methods; Recruitment Activity; Research; Resources; Science; South Carolina; Structure; Systems Biology; Time; Training; Training Programs; Translating; Translational Research; United States National Institutes of Health; Universities; Virginia; Washington; bioimaging; career; career development; clinical application; clinical phenotype; clinical translation; design; education research; externship; health disparity; innovation; meetings; multidisciplinary; novel; programs; skill acquisition; skills; symposium

Contact PD/PI: Guay-Woodford, Lisa Marie Inst-Career-Dev-001 (495) Project Summary Abstract   We propose a Mentored Career Development Plan that will utilize the resources of CTSI-CN v2.0 and our partner institutions, Children's National Health System, the George Washington University and Virginia Tech/Carilion Clinic. The focus of the KL2 program is on childhood disorders as precursors of adult disease. We propose an approach with team mentorship, multi-institutional courses and access to a large research skills development toolbox. It will also provide a strong portfolio of biomedical, health services, pharma, industry, and not-for-profit externships. Our research education paradigm utilizes blended learning that includes distance education and an online learning portal. Through the resources of the CTSA Scholarly Oversight Committee and the Grants Enhancement Program, the KL2 scholar will master CTR core competencies and be well prepared in all aspects of developing and submitting competitive NIH grant applications by the end of their training period. Of high priority is promoting diversity among recruited scholars and mentors, with specific strategies proposed for recruitment, retention and individualized supports. The KL2 scholar will: 1) complete graduate level courses in CTR, bioinformatics, systems biology, and health policy relevant to their area of research; 2) learn state-of-the-art laboratory, statistical, and epidemiological methodologies; 3) collect and analyze preliminary data with guidance from a Lead Mentor and Mentorship Team; 4) prepare and submit an NIH grant application; and 5) become versed in various strategies to translate their scientific findings into the next stages of clinical applications. Our proposed program ensures scholars will have 75% protected time. We draw on 48 mentors/co-mentors in affinity areas that include genomics/proteinomic with clinical phenotyping; chemical/biological/cellular therapies; biomedical imaging and engineering; rigorous clinical trials; and health disparities/health services research. Our scholars will participate in CTSA-network activities including a distance externship program initiated by the Medical University of South Carolina CTSA; our novel R25 curriculum entitled “Innovations in Pediatric CTR Education”; a planned R13- supported satellite conference for pediatric-focused KL2s at the annual Association for Clinical and Translation Science meeting, and a multidisciplinary consortium pilot program proposed in the CTSI-CN U54-application, the “Child Health Research Acceleration through Multisite Planning (CHAMP)”. The administrative structure of the KL2 includes a Project Lead and three Project Co-Leads with complementary skill sets in clinical research, team science/leadership, and educational design. We propose to select and train 9 scholars over the grant period, 4 with federal and 5 with institutional funding. We will use ongoing evaluation methods to continuously strengthen and refine out training program and measure its long-term impact on scientific careers and research contributions in CTR.

请联系PD/PI：Lisa Marie Inst-Career-Dev-001（495）Guay-Woodford， 项目摘要摘要   我们提出了一项指导的职业发展计划，该计划将利用CTSI-CN V2.0的资源和我们的资源 合作伙伴机构，儿童国家卫生系统，乔治华盛顿大学和弗吉尼亚州 技术/汽车诊所。 KL2计划的重点是作为成人疾病的前体儿童疾病。 我们提出了一种通过团队心态，多机构课程和大型研究的方法 技能开发工具箱。它还将提供强大的生物医学，健康服务，制药， 行业和非营利的实质性。我们的研究教育范式利用了混合学习 包括远程教育和在线学习门户。通过CTSA学术的资源 监督委员会和赠款增强计划，KL2学校将掌握CTR Core 能力并在开发和提交有竞争力的NIH赠款的各个方面做好准备 在培训期结束时申请。优先级是促进招募学者的多样性 和导师，并提出了针对招聘，保留和个性化支持的具体策略。 KL2 学校将：1）CTR，生物信息学，系统生物学和卫生政策的完整研究生级课程 与他们的研究领域有关； 2）学习最先进的实验室，统计和流行病学 方法; 3）在主要导师和指导的指导下收集和分析初步数据 团队; 4）准备并提交NIH赠款申请； 5）精通各种策略来翻译 他们的科学发现进入了临床应用的下一个阶段。我们提议的计划确保学者将 有75％的保护时间。我们在亲和力地区的48位导师/联合官员中绘制 带有临床表型的基因组/蛋白质组学；化学/生物/细胞疗法；生物医学成像和 工程;严格的临床试验；以及健康差异/健康服务研究。我们的学者将参加 在CTSA网络活动中，包括南方医科大学发起的距离实习计划 Carolina CTSA；我们的小说R25课程题为“小儿CTR教育的创新”；计划的R13- 在年度临床和翻译协会中，支持小儿的KL2卫星会议 科学会议，以及CTSI-CN U54申请中提出的多学科联盟试点计划 “通过多站点计划（Champ）的儿童健康研究加速”。的行政结构 KL2包括一个项目负责人和三位项目共同领导者，具有临床研究的完整技能， 团队科学/领导力和教育设计。我们建议选择和培训9个学者对赠款 时期为4，联邦为4，提供机构资金。我们将使用正在进行的评估方法继续 加强和完善培训计划，并衡量其对科学职业和研究的长期影响 CTR的贡献。