Hispanic Alliance for Clinical and Translational Research (Alliance)

西班牙裔临床和转化研究联盟（联盟）

• 批准号: 10876761
• 负责人: Carlos A. Luciano
• 金额: $ 7.43万
• 依托单位: UNIVERSITY OF PUERTO RICO MED SCIENCES
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-02 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10876761
• 关键词: Academia; Address; Adoption; Affect; Bioinformatics; Biometry; Cardiometabolic Disease; Clinical Research; Collaborations; Communicable Diseases; Communication; Communities; Community Health; Community Networks; Community Outreach; Dedications; Development; Development Plans; Disasters; Disease; Emerging Communicable Diseases; Ensure; Epidemiology; Ethnic Origin; Ethnic Population; Evaluation; Foundations; Funding; Generations; Goals; Government; Health; Health Sciences; Healthcare; Hispanic; Hispanic Populations; Human Resources; Infrastructure; Institution; Island; Knowledge; Laboratories; Leadership; Malignant Neoplasms; Medical; Mentors; Methods; Mission; Modeling; Outcome; Participant; Pilot Projects; Population; Positioning Attribute; Process; Public Health; Puerto Rico; Research; Research Design; Research Personnel; Resources; Safety; Science; Scientist; Services; Structure; System; Technology; Training; Training Activity; Translational Research; United States; United States National Institutes of Health; Universities; Work; biomedical informatics; career development; clinical translation; community engaged research; community engagement; community organizations; cyber infrastructure; data infrastructure; effective therapy; health care delivery; health data; hispanic community; improved; innovation; interdisciplinary collaboration; medical schools; medically underserved; next generation; programs; recruit; research and development; research facility; statistics; synergism; translational research program

Hispanic Alliance for Clinical & Translational Research (Alliance) ABSTRACT Improving health care for the medically underserved, including our Hispanic population, afflicted by prevalent diseases, such as cancer, cardio-metabolic and infectious diseases, remains a major challenge. The current supplement application is to support the development of Hispanic Alliance for Clinical & Translational Research in Puerto Rico (Alliance), which aims to build on the existing infrastructure of the Puerto Rico Clinical and Translational Research Consortium (the Alliance, PR-CTRC) and the unique expertise on emerging infectious diseases and strategic positioning for the study of disaster-related conditions and their impact on Health. The Alliance expands the scope of our successful decade long partnership by leveraging intellectual and physical resources of the three major academic health sciences centers on the Island: the University of Puerto Rico Medical Sciences Campus, the Universidad Central del Caribe, and the Ponce Medical School Foundation and key-collaborating institutions to support an integrated, island-wide program dedicated to the conduct clinical and translational research. The Alliance is founded on our hypothesis that research-driven improvements in health outcomes requires an integrated network of key stakeholders representing academia, government, community - based organizations, and health care delivery systems working together in an interdisciplinary, multi -sectorial clinical- translational research model. The objective of the Alliance is to serve as the catalytic center to enhance the competitiveness of investigators to conduct research and obtain additional funding for clinical and translational research addressing highly prevalent diseases and those that affect the medically underserved in PR. The long-term goal of the Alliance is to transform clinical and translational research in Hispanic populations in the mainland and in Puerto Rico by promoting inter-disciplinary collaboration and leverage of resources to address diseases affecting Hispanic communities.

西班牙裔临床和转化研究联盟（联盟） 摘要 改善医疗服务不足的人的医疗保健，包括我们的西班牙裔人口， 癌症、心脏代谢病和传染病等疾病仍然是一个重大挑战。当前 补充申请是为了支持西班牙裔临床和转化研究联盟的发展 在波多黎各（联盟），旨在建立在现有的基础设施的波多黎各临床和 转化研究联盟（联盟，PR-CTRC）和新兴传染病的独特专业知识 疾病和战略定位的研究与灾害有关的条件及其对健康的影响。的 联盟扩大了我们的成功的十年合作伙伴关系的范围，利用智力和体力 岛上三大学术健康科学中心的资源：波多黎各大学 中央加勒比大学医学院和庞塞医学院基金会， 主要合作机构，以支持一个综合的，全岛范围内的计划，致力于进行临床和 翻译研究该联盟建立在我们的假设之上，即研究驱动的健康改善 成果需要一个由代表学术界、政府、社区- 的组织和卫生保健提供系统在一个跨学科，多部门的合作， 临床-转化研究模式。联盟的目标是作为促进中心， 研究者进行研究和获得额外临床资金的竞争力， 针对高度流行的疾病和那些影响医疗服务不足的疾病的转化研究 PR.该联盟的长期目标是改变西班牙裔人群的临床和转化研究 在大陆和波多黎各，通过促进跨学科合作和利用资源， 解决影响西班牙裔社区的疾病。

项目成果

Multilayer subwavelength gratings or sandwiches with periodic structure shape light reflection in the tapetum lucidum of taxonomically diverse vertebrate animals.

• DOI: 10.1002/jbio.202200002
• 发表时间: 2022-06
• 期刊: JOURNAL OF BIOPHOTONICS
• 影响因子: 2.8
• 作者: Zueva, Lidia;Zayas-Santiago, Astrid;Rojas, Legier;Sanabria, Priscila;Alves, Janaina;Tsytsarev, Vassiliy;Inyushin, Mikhail
• 通讯作者: Inyushin, Mikhail

Longitudinal association between adiposity measures and regression of prediabetes/diabetes.

• DOI: 10.1016/j.numecd.2021.07.005
• 发表时间: 2021-10-28
• 期刊: Nutrition, metabolism, and cardiovascular diseases : NMCD
• 作者: Modi A;Gadhavi R;Pérez CM;Joshipura K
• 通讯作者: Joshipura K

Dental anomaly detection using intraoral photos via deep learning.

• DOI: 10.1038/s41598-022-15788-1
• 发表时间: 2022-07-08
• 期刊: SCIENTIFIC REPORTS
• 影响因子: 4.6
• 作者: Ragodos, Ronilo;Wang, Tong;Padilla, Carmencita;Hecht, Jacqueline T.;Poletta, Fernando A.;Orioli, Ieda M.;Buxo, Carmen J.;Butali, Azeez;Valencia-Ramirez, Consuelo;Restrepo Muneton, Claudia;Wehby, George L.;Weinberg, Seth M.;Marazita, Mary L.;Moreno Uribe, Lina M.;Howe, Brian J.
• 通讯作者: Howe, Brian J.

Coaching tailored by stages: A valuable educational strategy to achieve independence in research.

• DOI: 10.1017/cts.2021.804
• 发表时间: 2021
• 期刊: Journal of clinical and translational science
• 影响因子: 2.6
• 作者: Martínez KG;Jorge JC;Noboa-Ramos C;Estapé ES
• 通讯作者: Estapé ES

A genome-wide association study of asthma hospitalizations in adults.

• DOI: 10.1016/j.jaci.2020.08.020
• 发表时间: 2021-03
• 期刊: The Journal of allergy and clinical immunology
• 作者: Yan Q;Forno E;Herrera-Luis E;Pino-Yanes M;Yang G;Oh S;Acosta-Pérez E;Hu D;Eng C;Huntsman S;Rodriguez-Santana JR;Cloutier MM;Canino G;Burchard EG;Chen W;Celedón JC
• 通讯作者: Celedón JC