Wyoming Sensory Biology COBRE
Wyoming Sensory Biology COBRE
批准号:
10871969
负责人:
Qian-Quan Sun
金额:
$35.64万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
未结题
起止时间:
2017-09-01 至 2027-07-31
关键词:
AccelerationAddressAffectAgingAlzheimer&aposs DiseaseAlzheimer&aposs disease related dementiaAmyotrophic Lateral SclerosisAreaAutomobile DrivingAwardBRAIN initiativeBehaviorBioinformaticsBiologyBrainCenters of Research ExcellenceChildChronic DiseaseCollaborationsCollectionCommunicationCommunitiesComplexDataData AnalysesData CollectionData ScienceData SetDisciplineDiseaseDrug TargetingEcosystemEducationEducational workshopElectrophysiology (science)Environmental Risk FactorFosteringGene ExpressionGeneticGenetic VariationGenomicsGoalsGrantHumanImprove AccessInfrastructureInstitutionInvestmentsKnowledgeMissionModelingMolecularNeurodevelopmental DisorderNeuronsNeurosciencesNeurosciences ResearchParentsPatternProcessProductivityPublic HealthRecoveryResearchResearch InfrastructureResearch PersonnelResourcesSensorySensory DisordersSpinal cord injurySupercomputingTechniquesTechnologyTherapeuticTrainingTraining and EducationUniversitiesVisualizationWorkWyomingbasebrain healthcell typedata accessdata resourcedata sharingdevelopmental diseasehealth datainnovationinsightinstrumentinterdisciplinary collaborationlarge datasetslarge scale datamodels and simulationnervous system disordernovel markersensory systemsharing platformsimulationskillsspatial relationshiptooltraining opportunitytranscriptomics
中文摘要
总结
数据科学补充旨在实现NOT-OD-23-123的目标2,开发
怀俄明州大学的基础设施,以支持生物信息学中的大脑健康研究,
超级计算、建模、仿真、培训和教育。怀俄明州感官生物学
COBRE(WSBC)对人类感觉系统进行高质量的科学研究,
相关疾病,解决关键的公共卫生问题,如阿尔茨海默病。而数据
科学是至关重要的WSBC的研究目标,它不是一个主要组成部分的父
奖华盛顿大学欠发达的数据科学研究基础设施对以下方面提出了挑战:
WSBC的研究人员,阻碍了组学技术的利用。因此,这项建议
概述了三个具体目标:1)建立脑健康数据的机构基础设施
科学研究2)加强对受控组学和电生理学数据集的访问,
促进研究合作和培训。3)扩大数据科学研究基地,
促进跨学科合作。这些目标对当地产生了重大影响。
神经科学研究社区通过推动创新,推进大脑健康研究,
创造一个富有成效的研究生态系统。
英文摘要
Summary
The data science supplement aims to achieve objective 2 of NOT-OD-23-123, developing
infrastructure at the University of Wyoming to support brain health research in bioinformatics,
supercomputing, modeling, simulation, training, and education. The Wyoming Sensory Biology
COBRE (WSBC) conducts high-quality scientific research on human sensory systems and
related disorders, addressing critical public health issues like Alzheimer's disease. While data
science is crucial for WSBC's research goals, it was not a major component of the parent
award. The underdeveloped data science research infrastructure at UW poses challenges for
WSBC researchers, hindering the leveraging of omics technologies. Therefore, this proposal
outlines three specific aims: 1) Establishing institutional infrastructure for brain health data
science research. 2) Enhancing access to controlled omics and electrophysiology datasets,
promoting research collaboration and training. 3) Expanding research bases in data science and
fostering interdisciplinary collaboration. These aims have a significant impact on local
neuroscience research communities by driving innovation, advancing brain health research, and
creating a productive research ecosystem.
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DOI:
10.3389/fpsyt.2022.876749
发表时间:
2022
期刊:
FRONTIERS IN PSYCHIATRY
影响因子:
4.7
作者:
[Jun, Rachel, Zhang, Wen, Beacher, Nicholas J., Zhang, Yan, Li, Yun, Lin, Da-Ting]
通讯作者:
Lin, Da-Ting
Preparations and Protocols for Whole Cell Patch Clamp Recording of Xenopus laevis Tectal Neurons.
非洲爪蟾 Tectal 神经元全细胞膜片钳记录的制备和方案。
DOI:
10.3791/57465
发表时间:
2018
期刊:
Journal of visualized experiments : JoVE
影响因子:
--
作者:
[Liu,Zhenyu, Donnelly,KatelynneB, Pratt,KaraG]
通讯作者:
Pratt,KaraG
DOI:
10.3389/fncir.2021.762441
发表时间:
2021
期刊:
Frontiers in neural circuits
影响因子:
3.5
作者:
[Beacher NJ, Washington KA, Werner CT, Zhang Y, Barbera G, Li Y, Lin DT]
通讯作者:
Lin DT
DOI:
10.1038/sdata.2018.260
发表时间:
2018-12-04
期刊:
Scientific data
影响因子:
9.8
作者:
[Santoro SW, Jakob S]
通讯作者:
Jakob S
DOI:
10.3389/fnins.2023.1295998
发表时间:
2023
期刊:
FRONTIERS IN NEUROSCIENCE
影响因子:
4.3
作者:
[Jeffs, Quiana L., Prather, Jonathan F., Todd, William D.]
通讯作者:
Todd, William D.
共 17 条
A Long-range Recurrent Neural Network Mediates Threat Induced Innate Sensorimotor Integrations
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批准号:10539071
-
项目类别:
-
资助金额:$21.68万
-
财政年份:2022
-
负责人:Qian-Quan Sun
-
依托单位:
A Long-range Recurrent Neural Network Mediates Threat Induced Innate Sensorimotor Integrations
-
批准号:10626968
-
项目类别:
-
资助金额:$18.06万
-
财政年份:2022
-
负责人:Qian-Quan Sun
-
依托单位:
Core A: Administrative Core
-
批准号:10216276
-
项目类别:
-
资助金额:$80.22万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10395258
-
项目类别:
-
资助金额:$28.74万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10372244
-
项目类别:
-
资助金额:$35.09万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10398656
-
项目类别:
-
资助金额:$25.0万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10714606
-
项目类别:
-
资助金额:$35.65万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10216275
-
项目类别:
-
资助金额:$200.41万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Administrative Core
-
批准号:10923745
-
项目类别:
-
资助金额:$90.79万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10798707
-
项目类别:
-
资助金额:$25.0万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10118881
-
项目类别:
-
资助金额:$32.25万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Administrative Core
-
批准号:10892568
-
项目类别:
-
资助金额:$35.64万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10852744
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项目类别:
-
资助金额:$90.79万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Wyoming Sensory Biology COBRE
-
批准号:10164428
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项目类别:
-
资助金额:$14.45万
-
财政年份:2017
-
负责人:Qian-Quan Sun
-
依托单位:
Mechanisms underlying continuous spike-waves during slow-wave sleep in a mouse model of focal cortical dysplasia
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批准号:9008476
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项目类别:
-
资助金额:$30.28万
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财政年份:2015
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负责人:Qian-Quan Sun
-
依托单位:
Mechanisms underlying continuous spike-waves during slow-wave sleep in a mouse model of focal cortical dysplasia
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批准号:9281055
-
项目类别:
-
资助金额:$31.34万
-
财政年份:2015
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负责人:Qian-Quan Sun
-
依托单位:
Inhibitory Circuits Underlying Long-range Sensorimotor Integration
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批准号:8583267
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项目类别:
-
资助金额:$21.23万
-
财政年份:2013
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负责人:Qian-Quan Sun
-
依托单位:
Excitation and Inhibition Balance: Sensitive Period Plasticity
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批准号:8574483
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项目类别:
-
资助金额:$42.11万
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财政年份:2013
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负责人:Qian-Quan Sun
-
依托单位:
Mechanisms Underlying Maladaptive Organization of Long-range Epileptic Circuits A
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批准号:8569852
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项目类别:
-
资助金额:$20.19万
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财政年份:2013
-
负责人:Qian-Quan Sun
-
依托单位:
Inhibitory Circuits Underlying Long-range Sensorimotor Integration
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批准号:8710356
-
项目类别:
-
资助金额:$17.51万
-
财政年份:2013
-
负责人:Qian-Quan Sun
-
依托单位:
海外基金