2009 Vitamin B12 and Corphins Gordon Conference

描述(由申请者提供)：第四届戈登维生素B12和海豚研究会议将于2009年8月2日至7日在英国牛津大学马格达伦学院举行。这次会议是一个多学科会议，在欧洲(2005年在牛津举行)和美国(2007年在缅因州比德福德举行)之间轮流举行，反映了两大洲在维生素B12和Corphins领域的相当大的社区。2009年会议的主席是奥地利因斯布鲁克大学有机化学教授Bernhard Kréutler，副主席是来自美国马萨诸塞州剑桥市麻省理工学院的Catherine L.Drennan教授。2009年会议的目标是：1.邀请一群来自流行病学、毒理学、遗传学、生物化学、微生物学、化学和物理学等不同领域的科学家参加。他们都在维生素B12和海黄素领域的研究前沿工作。演讲的主题将有所不同，从疾病模型、营养、B12的摄取和运输，到B12辅因子和Corphins的酶催化机制。2.组织一次激动人心的会议，让不同社区和资深人士积极参与，讨论最新和最热门的事态发展，最重要的是分享从不同观点和背景获得的见解。增加的多学科互动也是为了促进合作。3.确保不断涌入新的想法和调查人员。为了实现这一目标，发言者名单主要由以前或最近没有发言的发言者组成，已经确定了几名初级和其他科学家，特别是博士后，他们将介绍他们的工作。 维生素B12辅因子是在寻找致命性贫血的原因后发现的，在医学上起着重要的作用。甲基丙二酸尿症和同型半胱氨酸尿症是维生素B12代谢的先天缺陷。此外，老年人中的B12营养不足与痴呆症有关。

DESCRIPTION (provided by applicant): The fourth biannual Gordon Research Conference on Vitamin B12 and Corphins will be held August 2-7, 2009, at Magdalen College, Oxford (UK). This conference is a multidisciplinary meeting that alternates between this European site (in 2005 it was held in Oxford) and the sites in the United States (in 2007 in Biddeford, Maine), reflecting the sizeable communities in the field of vitamin B12 and Corphins on both continents. The Chair of the 2009 meeting is Bernhard Kr¿utler, Professor of Organic Chemistry at the University of Innsbruck in Austria, with the vice- Chair being Prof. Catherine L. Drennan from the Massachusetts Institute of Technology (MIT), Cambridge, MA USA. The aims for the 2009 meeting are: 1. To feature a group of scientists from widely different fields including epidemiology, toxicology, genetics, biochemistry, microbiology, chemistry, and physics. All of them are working at the forefront of research in the fields of vitamin B12 and corphins. The topics presented will vary from disease models, nutrition, B12 uptake and transport, to mechanisms of enzyme catalysis with B12-cofactors and corphins. 2. To organize an exciting and stimulating conference in which the members of the different communities and seniorities actively participate, discuss the latest and hottest developments and most importantly, share insights obtained from diverse viewpoints and backgrounds. The increased multidisciplinary interactions are also intended to promote collaborations. 3. To ensure a continuing influx of new ideas and investigators. To achieve this, the speakers list has been made up mostly of speakers that have not spoken before or recently and several junior and other scientists, in particular postdocs, have been identified that will present on their work. The vitamin B12 cofactor, discovered as a result of the search for the cause of pernicious anemia, plays an important role in medicine. Conditions such as methylmalonic aciduria and homocystinuria are inborn errors of vitamin B12 metabolism. In addition, B12 nutritional deficiencies in the elderly are linked to dementia.