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CRYSTALLOGRAPHIC STUDIES OF NATURAL PRODUCT BIOSYNTHESIS

CRYSTALLOGRAPHIC STUDIES OF NATURAL PRODUCT BIOSYNTHESIS
天然产物生物合成的晶体学研究
批准号：
7955170
负责人：
CATHERINE L DRENNAN
金额：
$1.07万
依托单位：
CORNELL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-01 至 2010-03-31
来源：
https://reporter.nih.gov/project-details/7955170
关键词：
AnabolismBiological FactorsComputer Retrieval of Information on Scientific Projects DatabaseEnzymesFundingGoalsGrantInstitutionInvestigationPathway interactionsRebeccamycinResearchResearch PersonnelResourcesSourceStructureUnited States National Institutes of Healthbasestructural biologyviolacein

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中文摘要
翻译
这个子项目是众多研究子项目之一
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Our research was centered on using structure-based analysis to investigate enzymes involved in the biosynthesis of bisindole natural products. Our goal was to determine the structures of key enzymes in the biosynthetic pathways. We focused specifically on rebeccamycin and violacein biosynthesis, and we targeted the enzymes RebC, VioE, and VioD for structural investigations.
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Metalloenzyme structure, function and assembly
Metalloenzyme structure, function and assembly
Metalloenzyme structure, function and assembly
Metalloenzyme structure, function and assembly
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