Albany 2009: The 16th Conversation

奥尔巴尼 2009：第 16 次对话

• 批准号: 7742543
• 负责人: RAMASWAMY H SARMA
• 金额: $ 0.5万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT ALBANY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7742543
• 关键词: Aging; Alternative Splicing; Area; Biochemistry; Catalysis; Cell physiology; Chromatin; Communication; Cryoelectron Microscopy; DNA; Disease; Educational workshop; Epigenetic Process; Faculty; Female; Fire - disasters; Future; Gene Expression Regulation; Gene Silencing; Genome; Genomics; Hereditary Disease; Hour; Imagery; Informatics; Left; Macromolecular Complexes; Malignant Neoplasms; Medical; Nanotechnology; New York; Nucleosomes; Paper; Positioning Attribute; Postdoctoral Fellow; Protein Biosynthesis; Proteins; RNA; RNA Interference; Research Personnel; Ribosomes; Scientist; Selfish DNA; Senior Scientist; Structure; Systems Biology; Time; abstracting; base; design; embryonic stem cell; graduate student; human disease; innovation; lectures; nucleic acid structure; posters; programs; public health relevance; single molecule; structural biology; symposium; synthetic biology; tomography

DESCRIPTION (provided by applicant): Albany 2009: The 16th Conversation will be held in June 16-20 2009 at the State Univ. of New York at Albany. The Keynote evening lecture will be delivered by Nobel Laureate Andrew Fire, Stanford Univ. on RNA interference and nucleic acid structures associated with gene silencing. The Conversation will cover the following areas of structural biology: Alternative Splicing, Disordered Proteins and Embryonic Stem Cells; Genomics: System Biology and Networks; Chromatin and Epigenetics; RNA: Silencing of the Genome; RNA: Ribosome and Control of Protein Synthesis; RNA: Catalysis, Folding and Interactions; RNA: Structural Informatics; Repeats: Selfish DNA and Toxic RNA -Human Diseases; Protein-DNA, DNA-DNA, Protein- Protein Contacts and Gene Regulation; Proteins: Allostery, Network Communications and Design; Single Molecules Visualization at the Level of Cellular Processes; Innovation: Structure of Transients to Synthetic Biology; Ned Seeman's DNA Nanotechnology Session; Macromolecular complexes: cryo-electron microscopy & tomography. In addition a satellite workshop on Nucleosome Positioning will be held immediately following the Conversation. The subjects will be covered by invited lectures and poster discussion papers. There will be a total of 80 lectures, 56 by senior scientists and 24 by young researchers. Lectures by young researchers (graduate students, post-doctoral fellows and starting faculty) will be based on selection from abstracts submitted for poster presentation. 5.5 hours of the symposium time will be left vacant until abstracts for posters are received so that a significant number of lectures can be selected from the abstracts. The number of posters presented will be over 200. Out of a total of 80 talks, a minimum of 30 will be delivered by female scientists. The program will admit some 400 scientists from over 20 Nations. PUBLIC HEALTH RELEVANCE: Several of the sessions, such as Repeats: Selfish DNA and Toxic RNA -Human Diseases; Alternative Splicing, Disordered Proteins and Embryonic Stem Cells; Chromatin and Epigenetics; Protein-DNA, DNA-DNA, Protein-Protein Contacts and Gene Regulation; and Single Molecules Visualization at the Level of Cellular Processes deal directly with molecular diseases, and how one devises approaches to cure and manage them. The remaining topics look at advances in fundamental areas of medical biochemistry, and progress here will have profound impact on the way we will manage disease, including aging and cancer, in the future.

描述（由申请人提供）：奥尔巴尼2009年：第16次对话将于2009年6月16日至20日在纽约州立大学奥尔巴尼。当晚的主题演讲将由诺贝尔奖获得者、斯坦福大学的Andrew Fire发表，主题是RNA干扰和与基因沉默相关的核酸结构。对话将涵盖结构生物学的以下领域：选择性剪接，无序蛋白质和胚胎干细胞;基因组学：系统生物学和网络;染色质和表观遗传学; RNA：基因组的沉默; RNA：核糖体和蛋白质合成的控制; RNA：催化，折叠和相互作用; RNA：结构信息学;重复：自私的DNA和有毒的RNA -人类疾病;蛋白质-DNA，DNA-DNA，蛋白质-蛋白质接触和基因调控;蛋白质：Allostery，网络通信和设计;在细胞过程水平的单分子可视化;创新：合成生物学的瞬态结构; Ned Seeman的DNA纳米技术会议;大分子复合物：冷冻电子显微镜和断层扫描。此外，一个关于核小体定位的卫星研讨会将在对话后立即举行。这些主题将由特邀讲座和海报讨论文件涵盖。共有80场讲座，56场由资深科学家主讲，24场由年轻研究人员主讲。青年研究人员（研究生、博士后研究员和初级教员）的讲座将根据提交海报展示的摘要进行选择。5.5在收到海报的摘要之前，专题讨论会将空出几个小时的时间，以便从摘要中选择大量的演讲。提交的海报数量将超过200张。在总共80场演讲中，至少有30场将由女科学家主讲。该计划将接纳来自20多个国家的约400名科学家。 公共卫生关系：几个会议，如重复：自私的DNA和有毒的RNA -人类疾病;替代剪接，无序蛋白质和胚胎干细胞;染色质和表观遗传学;蛋白质-DNA，DNA-DNA，蛋白质-蛋白质接触和基因调控;和单分子可视化在细胞过程的水平直接处理分子疾病，以及如何设计治疗和管理它们的方法。其余的主题着眼于医学生物化学基本领域的进展，这里的进展将对我们未来管理疾病（包括衰老和癌症）的方式产生深远的影响。