Cellular Visualization and Analysis

RMTSC实验室的主要研究重点是使用特定的分子探针来描述化学感觉系统中的细胞组成和功能。该核心的主要功能是促进参与研究人员的研究，这些研究依赖于解剖学导向的方法来探索化学感觉上皮或主要参与化学感觉信息处理的神经中枢的组织，发育或功能。核心功能包含三个具体目标：1。支持和发展先进的组织学技术共聚焦与电子显微镜复杂解剖数据集的定量分析和可视化。虽然每个RMTSC实验室都将解剖学技术作为其整体研究计划的一部分，但并非所有实验室都具有使用双重标记，功能成像和电子显微镜等先进方法的同等机会或经验。这一核心促进了各实验室之间的专业知识分享，并使所有实验室都可以使用，而专门设施只能在一所参与大学中使用。核心不仅将为当地的RMTSC调查人员服务，而且还将作为一种资源

A major focus of research in the RMTSC laboratories is the use of specific molecular probes to delineate cellular composition and function in chemosensory systems. The major function of this core is to facilitate research of the participating investigators which relies on anatomically oriented methods to probe the organization, development or function of chemosensory epithelia or neural centers primarily involved in processing chemosensory information. The Core functions are encompassed by 3 specific Aims: 1. Support & Development of advanced histoiogical techniques 2. Confocal and Electron Microscopy 3. Quantitative Analysis and Visualization of Complex Anatomical Data Sets. Although each of the RMTSC laboratories utilizes anatomical techniques as a part of their overall research program, not all laboratories have equal access or experience in using advanced methodologies such as dual-labeling, functional imaging and electron microscopy. This Core facilitates sharing of expertise among the laboratories and makes available to all, specialized facilities available only at one of the participating Universities. Not only will the Core serve the local RMTSC investigators, but it will also serve as a resource for other chemosensory researchers especially in regards to development of software for mapping chemosensory representation in the brain.