Human Subjects Core

人类受试者核心

• 批准号: 7510456
• 负责人: Robert D Frisina
• 金额: $ 10.38万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-23 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7510456
• 关键词: Age; Alzheimer' s Disease; Ataxia; Cognitive; Collaborations; Communication; Credentialing; Data; Databases; Degenerative Disorder; Faculty; Family; Goals; Grant; Growth; Guidelines; Hearing; Individual; Informed Consent; Inherited; Laboratories; Medical; Motor; Neurologic; Patients; Physiological; Population; Procedures; Productivity; Protocols documentation; Range; Rate; Records; Research; Research Personnel; Research Project Grants; Research Subjects; Schedule; Science; Screening procedure; Seasons; Sensorineural Hearing Loss; Sensory; Services; Structure; Students; Target Populations; Time; Training; Universities; Vision; human study; human subject; nervous system disorder; novel; research study; tool

A variety of research projects within the Core-Center employ human subjects. The Human Subjects Core (HSC) greatly facilitates our collective research goals by centralizing a set of common procedures, operated by a seasoned staff that interact effectively with both the subjects and with faculty, students, and laboratory staff within the research studies supported by the Core. The Core provides several key services. First, the Core coordinates recruitment and screening of human subjects across research projects (normal and patient). This includes identifying subjects and obtaining informed consent, followed by basic medical and sensorimotor/neurologic exams, as well as physiologic and cognitive screening relevant to the populations targeted by Core studies. Populations now under study include normal subjects across a broad range of ages, subjects with specific neurological disorders (e.g. inherited ataxias, Alzheimer's and other degenerative diseases), and subjects with specific sensory loss (hearing, vision, vestibular), but otherwise healthy. Second, the Core coordinates scheduling and tracking across projects in order to maximize efficiency and convenience for subjects, investigators and staff. Further, the use of common subjects across studies supplies novel and paired observations that enhance productivity and stimulate new and collaborative research. Third, the Core maintains a powerful modern database that provides protected access to data and analytic tools for investigators and staff. This central service promotes new studies while making existing ones more efficient. Fourth, Core services include the coordination of protocol approvals, staff credential ing, and record keeping required of all human studies. The above services and tasks are made exceedingly efficient by a centralized structure orchestrated by a seasoned and trained staff. The benefits unload time and effort for faculty and staff to pursue more directly relevant research goals, and simultaneously catalyze new projects and collaborations. This is apparent in the growth of human studies in the Core-Center, including those by new faculty and ongoing ones alike.

核心中心内的各种研究项目采用人类受试者。人类受试者 核心（HSC）通过集中一组公共程序， 由经验丰富的工作人员，有效地互动与双方的主题和教师，学生， 实验室工作人员在研究的核心支持。核心提供几项关键服务。 首先，核心协调整个研究中人类受试者的招募和筛选 项目（正常和患者）。这包括确定受试者并获得知情同意， 通过基本的医学和感觉运动/神经系统检查，以及相关的生理和认知筛查， 核心研究的目标人群。目前正在研究的人群包括跨年龄段的正常受试者。 广泛的年龄范围，患有特定神经系统疾病（例如遗传性共济失调、阿尔茨海默病和 其他退行性疾病）和具有特定感觉丧失（听力、视力、前庭）的受试者，但 其他方面都很健康 第二，核心协调跨项目的进度安排和跟踪，以最大限度地 为受试者、研究者和工作人员提供效率和便利。此外，跨学科的共同主题的使用 研究提供了新的和成对的观察，提高生产力，激发新的和 合作研究。 第三，核心维护一个强大的现代数据库，提供受保护的数据访问， 调查人员和工作人员的分析工具。这项中央服务促进新的研究，同时使现有的 更有效率。 第四，核心服务包括协议审批协调、人员认证和 所有人体研究均需保存记录。 上述服务和任务通过一个集中的结构来实现， 经验丰富训练有素的员工这些好处使教职员工可以更直接地追求时间和精力 相关的研究目标，并同时催化新的项目和合作。这一点在《 核心中心的人类研究的增长，包括新教师和正在进行的研究。