Clinical Research and Assay Support

临床研究和检测支持

• 批准号: 7734330
• 负责人: Mary Walter
• 金额: $ 42.55万
• 依托单位: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7734330
• 关键词: Aliquot; Biological Assay; Clinical Investigator; Clinical Research; Contracts; Core Facility; Databases; Diabetes Mellitus; Goals; Human; Institutes; Instruction; Intramural Research Program; Kidney Diseases; Label; Leptin; Measures; Methods; Nonesterified Fatty Acids; Numbers; Plasma; Principal Investigator; Process; Protocols documentation; Research Personnel; Running; Sampling; Services; Shipping; Ships; Site; Specimen; System; Testing; Week; des-n-octanoyl ghrelin; ghrelin; glucagon-like peptide 1

The Clinical Research Core is responsible for processing human samples from numerous clinical studies currently in progress. Once the samples are acquired we process it according to the instructions on the protocol, aliquot, label and store the samples for the various principal investigators as per their instructions. We are currently processing an average of 986 samples/week. All samples processed in the lab are set up with a tracking number and entered into a database which is maintained by the Core lab. Studies that have started since January 2008 are labeled using a 2D-barcode system developed in our lab. The Core lab has also set up a biorepository service with Fisher Bioservices for long term off-site storage of samples. In addition to the biorepository needs of the PIs, the Clinical Research Core also provides assay services for analyses which are currently not available at DLM. We have tested and validated numerous methods to measure Glucagon-like Peptide-1, Acyl Ghrelin, Desacyl Ghrelin, Leptin and Free fatty acid in human plasma.

临床研究核心负责处理目前正在进行的大量临床研究中的人体样本。一旦采集到样本，我们就会根据规程上的说明进行处理，并根据首席调查员的指示对样本进行等量、标记和储存。我们目前平均每周处理986个样品。在实验室处理的所有样品都设置了跟踪号，并输入了由Core实验室维护的数据库。自2008年1月开始的研究使用我们实验室开发的2D条形码系统进行标记。核心实验室还与费希尔生物服务公司建立了一项生物储存库服务，用于长期非现场存储样本。 除了PIS的生物储存库需求外，临床研究核心还为DLM目前无法提供的分析提供分析服务。我们已经测试和验证了许多方法来测定人血浆中的胰高血糖素样肽-1、酰基生长素、去脂酰生长素、瘦素和游离脂肪酸。