Clinical Research and Assay Support

临床研究和检测支持

• 批准号: 8149684
• 负责人: Mary Walter
• 金额: $ 120.94万
• 依托单位: NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8149684
• 关键词: Biological Assay; Clinical Research

The Clinical Research Core is responsible for processing human samples from numerous clinical studies currently in progress. Once the samples are acquired we process it according to the instructions on the protocol, aliquot, label and store the samples for the various principal investigators as per their instructions. We are currently processing an average of 986 samples/week. All samples processed in the lab are set up with a tracking number and entered into a database which is maintained by the Core lab. Studies that have started since January 2008 are labeled using a 2D-barcode system. In addition to the biorepository needs of the PIs, the Clinical Research Core also provides assay services for analyses which are currently not available at DLM. We have tested and validated numerous methods to measure total and active Glucagon-like Peptide-1, Acyl Ghrelin, Desacyl Ghrelin, Leptin, Adiponectin, Oxyntomodulin and several other markers in human plasma.

临床研究核心负责处理目前正在进行的众多临床研究中的人体样本。 一旦获得样本，我们就会根据方案上的说明对其进行处理，按照各主要研究人员的指示等分、标记和存储样本。 目前我们平均每周处理 986 个样本。 实验室处理的所有样品均设置有跟踪编号，并输入由核心实验室维护的数据库中。自 2008 年 1 月开始的研究使用二维条形码系统进行标记。 除了 PI 的生物样本库需求外，临床研究核心还提供 DLM 目前无法提供的分析服务。 我们已经测试和验证了多种方法来测量总的和活性的胰高血糖素样肽-1、酰基生长素释放肽、去酰基生长素释放肽、瘦素、脂联素、泌酸调节素和人血浆中的几种其他标记物。