Enhancing Participation of Historically Minoritized Groups in Alzheimer Disease and Related Dementias Research

项目摘要/摘要 题为“加强阿尔茨海默氏症历史上少数群体的参与”的全国会议 疾病及相关痴呆症研究“，在本申请中提出，代表有意(但COVID 大流行延迟)2018年全国研讨会的后续行动，“非裔美国人参与阿尔茨海默氏症 研究：有效战略“，2018年10月10日在圣路易斯华盛顿大学(吴)举行。这个 研讨会由R13 AG059415(JC Morris，Pi)资助，由吴氏阿尔茨海默病骑士主办 研究中心(ADRC)。2018年研讨会的听众包括来自国家(例如， 国家老龄研究所、阿尔茨海默氏症协会和非洲裔美国人抗阿尔茨海默氏症 网络)和圣路易斯社区(例如，骑士ADRC非裔美国人咨询委员会、圣路易斯社区 路易神职人员联盟和The Links，Inc.圣路易斯分会)致力于 提高了解、可靠诊断和有效治疗阿尔茨海默病的研究工作的多样性 和相关痴呆症(ADRD)。然而，主要的听众是每个NIA的领导层- 资助ADRC，因为ADRC网络支持招募、登记、评估和 纵向跟踪，以提供对ADRD的科学研究至关重要的数据和生物谱。 拟议的会议将于2023年10月12日至13日在圣路易斯的华盛顿大学举行，以 解决区域发展报告中仍然缺乏协调战略以确保适当征聘的问题， 参与和保留来自历史上少数群体的研究参与者。一共有四个 会议目标：1)使ADRC网络采用统一的定义、术语和语言，用于 在ADRD研究中对人口进行小型化；2)审查获得社会调查数据的新电池 促进消除种族歧视的种族和族裔差异的健康决定因素；3)鼓励消除种族歧视委员会 网络，以解决社区发起的研究课题；以及4)使ADRC网络纳入 统一框架，以加强招募、聘用和留住小规模团体的人员 在ADRD研究中。迄今为止，拟议会议已获得6名主持人(2名妇女；3名妇女)的接受。 黑人，1名亚裔，1名西班牙裔/拉丁裔)和22名发言者(15名女性，8名黑人，3名亚洲人，1名美国印第安人/阿拉斯加人 原住民；2西班牙裔/拉丁裔/x/a)。会议制定的有效战略将由 红十字与红新月会网络不仅向广大科学界传播。

Project Summary/Abstract The national Conference, entitled “Enhancing Participation of Historically Minoritized Groups in Alzheimer Disease and Related Dementias Research”, proposed in this application represents the intentional (but COVID pandemic-delayed) follow-up to the 2018 national Workshop, “African American Participation in Alzheimer Research: Effective Strategies”, held at Washington University (WU) in St. Louis on October 10th, 2018. The Workshop was funded by R13 AG059415 (JC Morris, PI) and was hosted by WU’s Knight Alzheimer Disease Research Center (ADRC). The audience for the 2018 Workshop included representatives from national (e.g., the National Institute on Aging, the Alzheimer’s Association, and the AfricanAmericansAgainstAlzheimer’s Network) and St. Louis community (e.g., the African American Advisory Board for the Knight ADRC, the St. Louis Clergy Coalition, and the St. Louis Chapter of the Links, Inc.) organizations that are committed to improving diversity in research efforts to understand, reliably diagnose, and effectively treat Alzheimer Disease and Related Dementias (ADRD). However, the primary audience was the leadership of each of the NIA- funded ADRCs as the ADRC network supports the clinical cohorts that are recruited, enrolled, assessed, and longitudinally followed to provide the data and biospecimens that are essential for scientific studies in ADRD. The proposed Conference will be held at Washington University in St. Louis on October 12-13, 2023, to address the continuing lack in the ADRCs of coordinated strategies to ensure the appropriate recruitment, engagement, and retention of research participants from historically minoritized populations. There are four Conference objectives: 1) to have the ADRC network adopt uniform definitions, terms, and language for use for minoritized populations in ADRD research; 2) to review new batteries that obtain data on the social determinants of health that contribute to racial and ethnic differences in ADRD; 3) to encourage the ADRC network to address community-initiated research topics; and 4) to have the ADRC network incorporate a uniform framework to enhance the recruitment, engagement, and retention of persons from minoritized groups in ADRD research. To date, the proposed Conference has acceptances from 6 Moderators (2 women; 3 Black, 1 Asian; 1 Hispanic/Latinx) and 22 speakers (15 women; 8 Black, 3 Asian, 1 American Indian/Alaska Native; 2 Hispanic/Latino/x/a). The effective strategies developed by the Conference will be used by the ADRC network but also disseminated to the scientific community at large.