MRI System for Neuroimaging Typical and Atypical Cognitive and Social Development

用于神经影像典型和非典型认知和社会发展的 MRI 系统

• 批准号: 7498224
• 负责人: MARCEL Adam JUST
• 金额: $ 200万
• 依托单位: CARNEGIE-MELLON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-13 至 2011-05-12
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7498224
• 关键词: Address; Area; Arts; Autistic Disorder; Brain; Clinical; Cognition; Cognitive; Computer Simulation; Development; Discipline; Dyslexia; Emotional; Funding; Health; Human; Institution; Language Pathology; Magnetic Resonance Imaging; Mind; Personal Satisfaction; Research; Scientist; Social Development; Social Functioning; Stroke; Support System; System; Techniques; Translational Research; United States National Institutes of Health; Universities; Work; base; cognitive neuroscience; improved; insight; instrument; language processing; method development; neurodevelopment; neuroimaging; programs; public health relevance; relating to nervous system; social neuroscience

DESCRIPTION (provided by applicant): This proposal seeks support to acquire a state-of-the-art Siemens Trio 3 Tesla MRI scanner system for the study of the brain systems underpinning various aspects of human cognitive and social functioning, as well as their typical and atypical development. Clinical and basic scientists from multiple disciplines and institutions stand poised to use the proposed scanner system to make field-leading contributions in the context of furthering their National Institutes of Health-funded, translational research programs. These research programs address critical questions in a number of areas including the cognitive neuroscience of autism, developmental cognitive neuroscience, aspects of high-level cognition, language processing and language pathology, MRI methods development, social neuroscience, and computational modeling of cognition and brain function. Scientists at Carnegie Mellon University and the University of Pittsburgh have been at the forefront of advances in MRI-based techniques particularly as they are applied to understanding the human mind and its development. While much progress has been made, fundamental questions about typical and atypical brain function remain to be addressed with the help of the requested instrument. PUBLIC HEALTH RELEVANCE: The work to be supported by the proposed MRI system focuses on the neural systems supporting cognitive and social functions, which are at the center of our emotional and intellectual well-being. In atypical neural systems, such as in autism, dyslexia, and stroke, the planned research will provide fundamental new insights that will help to improve human health and well-being. Many of the research programs that this scanner would support are in close concordance with current areas of emphasis for NIH, including autism, social neuroscience, and neurodevelopment.

描述(由申请人提供)：这项提案寻求支持，以获得最先进的西门子Trio 3特斯拉磁共振成像扫描系统，用于研究支撑人类认知和社会功能的各个方面的大脑系统，以及它们的典型和非典型发育。来自多个学科和机构的临床和基础科学家准备使用拟议的扫描仪系统，在推进他们的国家卫生研究院资助的翻译研究计划的背景下做出领域领先的贡献。这些研究项目涉及多个领域的关键问题，包括自闭症的认知神经科学、发展认知神经科学、高级认知方面、语言处理和语言病理学、磁共振成像方法开发、社会神经科学以及认知和大脑功能的计算建模。卡内基梅隆大学和匹兹堡大学的科学家一直处于基于磁共振成像技术进步的前沿，特别是在它们被应用于理解人类大脑及其发育的时候。虽然已经取得了很大的进展，但关于典型和非典型脑功能的基本问题仍有待于在所要求的仪器的帮助下解决。与公共健康相关：拟议的MRI系统将支持的工作重点是支持认知和社会功能的神经系统，这是我们情绪和智力健康的中心。在非典型神经系统中，如自闭症、阅读障碍和中风，计划中的研究将提供基本的新见解，有助于改善人类的健康和福祉。该扫描仪支持的许多研究项目与NIH目前的重点领域非常一致，包括自闭症、社会神经科学和神经发育。