Oncogenic Signaling and Cancer Therapy

致癌信号和癌症治疗

• 批准号: nhmrc : 1053792
• 负责人: Prof Grant Mcarthur
• 金额: $ 531.41万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Program Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/oncogenic-signaling-cancer-therapy/112350
• 关键词: Oncogenic; Signaling; Cancer; Therapy

Central to improving the management of patients with cancer is an understanding of the molecular drivers of cancer. Based on our fundamental discoveries about the role of cell growth and perturbed cell signalling as drivers of cancer we will use the integration of molecular and imaging biomarkers with targeted therapies to translate this knowledge into better outcomes for cancer patients with defined molecular drivers of their cancer.

改善癌症患者管理的核心是了解癌症的分子驱动因素。基于我们对细胞生长和干扰细胞信号传导作为癌症驱动因素的作用的基本发现，我们将使用分子和成像生物标志物与靶向治疗的整合，将这些知识转化为具有明确的癌症分子驱动因素的癌症患者的更好结果。