A Bridge to Treatment for Out-of-Treatment Injection Heroin Users

为停止治疗的注射海洛因使用者提供治疗的桥梁

基本信息

  • 批准号:
    7848886
  • 负责人:
  • 金额:
    $ 64.38万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2007
  • 资助国家:
    美国
  • 起止时间:
    2007-09-30 至 2012-05-31
  • 项目状态:
    已结题

项目摘要

DESCRIPTION (provided by applicant): Injection drug use is a common mode of HIV transmission. Methadone can reduce injection heroin use and injection-related HIV risk behaviors, but most injection heroin users are difficult to engage in treatment. A randomized study is planned over 5 years to evaluate the effectiveness of the Therapeutic Workplace in promoting engagement in methadone treatment and increasing drug abstinence in unemployed, out-of- treatment, injection heroin users. The Therapeutic Workplace is a novel employment-based intervention that uses wages for work to reinforce clinically important behavior change. Workplace participants are paid to work in a supported workplace. To promote clinically important behaviors, wages are arranged contingent both on work and those behaviors. In this study, participants will be invited to attend the workplace and enroll in methadone treatment. During a workplace induction period, participants will be allowed to work and earn wages independent of whether they enroll in methadone treatment and independent of their drug use. After 4 weeks, workplace participants (N = 162) will be randomly assigned to one of three groups. All groups will be invited to attend the workplace for 26 weeks. "Methadone Contingency" participants will be required to take methadone to work, and will receive a brief pay decrease for missing a dose. Because many heroin users also use cocaine, even during methadone treatment, "Methadone and Abstinence Contingency" participants will be required to take methadone to work, and will receive a brief pay decrease for missing a methadone dose or for providing a cocaine-positive urine sample. "Usual Care" participants will be allowed to work independent of their methadone use or urinalysis results. We expect that the "Methadone Contingency" group will increase methadone adherence and decrease heroin use; and that the "Methadone and Abstinence Contingency" group will increase methadone adherence, and decrease heroin and cocaine use. Since methadone is effective at retaining patients in treatment once enrolled, we expect that once the "Methadone Contingency" engages participants in methadone treatment, the methadone will serve to maintain their participation in treatment after exposure to the Therapeutic Workplace ends. The Therapeutic Workplace could serve as a bridge to engage out-of-treatment injection heroin users into methadone treatment, and to reduce their drug use and injection-related HIV risk behaviors.
描述(申请人提供):注射吸毒是一种常见的艾滋病毒传播方式。美沙酮可以减少注射海洛因的使用和注射相关的艾滋病毒危险行为,但大多数注射海洛因使用者很难从事治疗。计划在5年内进行一项随机研究,以评估治疗工作场所在促进参与美沙酮治疗和增加失业、未接受治疗的注射海洛因吸毒者戒毒方面的有效性。治疗工作场所是一种新型的以就业为基础的干预措施,它使用工作工资来加强临床上重要的行为改变。工作场所参与者在支持的工作场所工作是有报酬的。为了促进临床上重要的行为,工资是根据工作和这些行为安排的。在这项研究中,参与者将被邀请参加工作场所并参加美沙酮治疗。在工作场所入职期间,参与者将被允许工作和赚取工资,无论他们是否参加美沙酮治疗,也与他们的药物使用无关。4周后,工作场所参与者(N=162)将被随机分配到三组中的一组。所有团体都将被邀请参加为期26周的工作场所。“美沙酮应急”参与者将被要求服用美沙酮上班,并将因错过一剂药物而获得短暂的减薪。由于许多海洛因使用者也使用可卡因,即使在美沙酮治疗期间,“美沙酮和戒毒应急”参与者将被要求服用美沙酮上班,并将因错过美沙酮剂量或提供可卡因阳性尿样而获得短暂的减薪。“日常护理”参与者将被允许独立于他们的美沙酮使用或尿液分析结果而工作。我们预期“美沙酮应变”组会增加美沙酮的依从性,减少海洛因的使用;而“美沙酮和戒毒应变”的组会增加美沙酮的依从性,减少海洛因和可卡因的使用。由于美沙酮在登记后能有效地留住病人接受治疗,我们预期一旦“美沙酮应急计划”促使参与者接受美沙酮治疗,美沙酮将可在暴露于治疗工场结束后维持他们继续参与治疗。治疗工作场所可以作为一座桥梁,让未接受治疗的注射海洛因使用者参与美沙酮治疗,并减少他们的吸毒和与注射有关的艾滋病毒危险行为。

项目成果

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Kenneth Silverman其他文献

Kenneth Silverman的其他文献

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{{ truncateString('Kenneth Silverman', 18)}}的其他基金

Long-Term Treatment of Opioid Use Disorder
阿片类药物使用障碍的长期治疗
  • 批准号:
    10371356
  • 财政年份:
    2022
  • 资助金额:
    $ 64.38万
  • 项目类别:
Long-Term Treatment of Opioid Use Disorder
阿片类药物使用障碍的长期治疗
  • 批准号:
    10598546
  • 财政年份:
    2022
  • 资助金额:
    $ 64.38万
  • 项目类别:
Incentives for Suppression of HIV-1 RNA in People Living with HIV
抑制 HIV 感染者中 HIV-1 RNA 的激励措施
  • 批准号:
    8846864
  • 财政年份:
    2015
  • 资助金额:
    $ 64.38万
  • 项目类别:
Abstinence-Contingent Wage Supplements for Long-Term Treatment of Drug Addiction
用于长期治疗毒瘾的戒断工资补贴
  • 批准号:
    9220802
  • 财政年份:
    2015
  • 资助金额:
    $ 64.38万
  • 项目类别:
Incentives for Suppression of HIV-1 RNA in People Living with HIV
抑制 HIV 感染者中 HIV-1 RNA 的激励措施
  • 批准号:
    9194382
  • 财政年份:
    2015
  • 资助金额:
    $ 64.38万
  • 项目类别:
A Bridge to Treatment for Out-of-Treatment Injection Heroin Users
为停止治疗的注射海洛因使用者提供治疗的桥梁
  • 批准号:
    7501320
  • 财政年份:
    2007
  • 资助金额:
    $ 64.38万
  • 项目类别:
A Bridge to Treatment for Out-of-Treatment Injection Heroin Users
为停止治疗的注射海洛因使用者提供治疗的桥梁
  • 批准号:
    8081710
  • 财政年份:
    2007
  • 资助金额:
    $ 64.38万
  • 项目类别:
A Bridge to Treatment for Out-of-Treatment Injection Heroin Users
为停止治疗的注射海洛因使用者提供治疗的桥梁
  • 批准号:
    7643431
  • 财政年份:
    2007
  • 资助金额:
    $ 64.38万
  • 项目类别:
A Bridge to Treatment for Out-of-Treatment Injection Heroin Users
为停止治疗的注射海洛因使用者提供治疗的桥梁
  • 批准号:
    7339450
  • 财政年份:
    2007
  • 资助金额:
    $ 64.38万
  • 项目类别:
Employment-Based Addiction Pharmacotherapy
基于就业的成瘾药物治疗
  • 批准号:
    6852277
  • 财政年份:
    2005
  • 资助金额:
    $ 64.38万
  • 项目类别:

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