Center for End-of-Life Transition Research (CEoLTR)

描述（由申请人提供）：生命末期过渡研究中心的总体目的是推进对整个生命周期面临生命末期过渡的人的护理科学（例如，婴儿出生死亡，儿童，成人和老年人）。我们将强调以病人为中心，以家庭为中心的尊重死亡，规划与病人和家庭的价值观和优先事项一致的临终关怀（例如，对人们死亡方式的认识和提前的护理计划）和预期的死亡经历（例如，临终关怀、临终关怀和丧亲之痛）。本中心申请之具体捐献为：（1）促进与生命末期过渡相关之护理科学;（2）加强质量和数量的道德使用中心研究者/附属机构的（混合方法）方法，并培训新手关于临终研究中的伦理问题和生物行为的混合方法测量（生物、行为和经验）变量、数据管理和数据分析;（3）利用信息学解决方案扩大进行寿命终了研究的能力，这些解决方案有助于实现高度完整的流程和高效、有效、和可靠的结果在机构和社区为基础的设置;和（4）促进传播的生命结束的研究结果，以科学和临床社区和公众。由该中心支持的研究将被设计为：（一）阐明潜在的生理，经验和行为机制，间接或影响接近死亡或丧亲之痛;和（B）测试文化相关的干预措施，死亡意识和尊重死亡。由该中心支持的研究将有一个生物行为的方向，并将包括结束生命护理的概念，测量生理（生物功能），经验（症状，感知健康，生活质量），和行为（功能状态）。修订申请增加了护理和医疗保健 信息学核心通过增加多媒体数据分析和可视化以及数据挖掘的能力，以及工程学院教师的大量专业知识。

DESCRIPTION (provided by applicant): The overall purpose of the Center for End-of-Life Transition Research is to advance the science of care for people facing the end-of-life transition across the life span (e.g., babies born dying, children, adults, and older adults). We will emphasize patient-centered, family-focused respectful death with planning for end-of-life care that is consistent with the patients' and families' values and priorities (e.g., awareness about ways people die and advance care planning) and expected death experiences (e.g., palliative care, approaching dying, and bereavement). The specific alms of this Center application are to: (1) advance nursing science related to the end-of-life transition; (2) strengthen the ethical use of qualitative and quantitative (mixed methods) methodologies by Center investigators/affiliates and train novices regarding the ethical Issues in end of life research and mixed methods measurement of biobehavioral (biological, behavioral, and experiential) variables, management of data, and analysis of data; (3) expand the capacity to conduct end-of-life research with Informatics solutions that contribute to high integrity processes and efficient, valid, and reliable outcomes In Institutional and community-based settings; and (4) facilitate the dissemination of end-of-life research findings to the scientific and clinical communities and to the general public. Studies supported by the Center will be designed to: (a) elucidate underlying physiological, experiential, and behavioral mechanisms that prognosticate or influence approaching death or bereavement; and (b) test culturally relevant interventions for death awareness and respectful death. The research supported by the Center will have a biobehavioral orientation and will Include end-of life-care concepts that are measured physiologically (biologic function), experientially (symptoms, perceived health, quality of life), and behaviorally (functional status). The revision application adds to the Nursing and Healthcare Informatics Core by adding capacity for multimedia data analysis and visualization and data mining with substantial added expertise from faculty from the College of Engineering.