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TRANSGENIC MOUSE FACILITY (SHARED RESOURCE)

TRANSGENIC MOUSE FACILITY (SHARED RESOURCE)
转基因小鼠设施（共享资源）
批准号：
7944541
负责人：
Arthur D Lander
金额：
$5.07万
依托单位：
UNIVERSITY OF CALIFORNIA-IRVINE
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
项目状态：
已结题
起止时间：
2009-04-06 至 2012-01-31
来源：
https://reporter.nih.gov/project-details/7944541
关键词：
AgeAllelesAneuploidyAnimal ModelAntibiotic ResistanceApplications GrantsBackBase PairingBreedingCancer BiologyCancer Center Support GrantCancer ModelCancer Research ProjectCell Culture TechniquesCell LineCell LineageCellsCharacteristicsChimera organismChromosomesClientCodeComplexConsultationsCryopreservationDNADerivation procedureDevelopmentDiseaseES Cell LineElectroporationEmbryoEmbryo TransferEngineeringEquipmentEventFeesFemaleFertilization in VitroFosteringFreezingFundingGene ExpressionGene TargetingGenesGenomeGenomicsGenotypeGoalsGrantGreen Fluorescent ProteinsGrowthHandHarvestHeadHealth StatusHourIn VitroIndividualInjection of therapeutic agentInstitutionIntentionKaryotypeKaryotype determination procedureKnock-in MouseKnock-outKnowledgeLacZ GenesLettersLifeLinkLocationMalignant NeoplasmsMeasuresMethodsMicroinjectionsMissionMolecularMothersMouse StrainsMusMutationNatureNon-Commercial SourcesOocytesOutcomePartner in relationshipPatternPhenotypePlasmidsPositioning AttributeProcessProteinsReporter GenesResearchResearch PersonnelResistanceResource SharingResourcesRoleServicesSiteSouthern BlottingStagingStretchingTailTechnologyTemperatureTimeTissuesTransgenesTransgenic MiceTransgenic Mouse FacilityUniversity of California Irvine Cancer CenterWorkbaseblastocystcostembryonic stem cellexperiencehomologous recombinationhuman diseasein vivointerestmature animalmemberoffspringpathogenpluripotencypreimplantationpromoterrecombinasetransmission process

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中文摘要
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英文摘要
The mission of the Transgenic Mouse Facility at UC-lrvine is to facilitate the use of genetically modified mice in hypothesis-driven research by providing services for making, breeding, genotyping, importing, and preserving mouse strains. Our primary goal is to offer these services at the lowest possible cost while producing yields and outcomes that compare favorably with similar facilities at other academic institutions. We are in a strong position to assist in the development of in vivo mammalian models of cancer and to provide strains of mice that are critical to understanding the molecular basis of cancer.
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