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Optimisation of a potent and fast acting antimalarial class that is orally efficacious in vivo

Optimisation of a potent and fast acting antimalarial class that is orally efficacious in vivo
优化一种有效且快速起效的抗疟药物,该药物在体内口服有效
批准号:
nhmrc : 1135421
负责人:
A/Pr Justin Boddey
金额:
$46.24万
依托单位国家:
澳大利亚
项目类别:
Development Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2019-12-31

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中文摘要
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英文摘要
Malaria is a devastating disease that results in 600 000 deaths annually. Current therapeutics used to combat malaria have a limited duration of use in the clinic due to the onset of resistance. We have identified a highly active antimalarial series that we propose to further develop to meet the prerequisites required for partnership with the Medicines for Malaria Venture (MMV) for progression into the clinic.
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会议论文
Role of plasmepsin V and PTEX complex in Plasmodium liver infection
  • 批准号:
    nhmrc : GNT1139153
  • 项目类别:
    Project Grants
  • 资助金额:
    $84.84万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Justin Boddey
  • 依托单位:
The role of protein glycosylation in the malaria parasite
The role of protein glycosylation in the malaria parasite
  • 批准号:
    nhmrc : GNT1139546
  • 项目类别:
    Project Grants
  • 资助金额:
    $64.44万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Justin Boddey
  • 依托单位:
Role of plasmepsin V and PTEX complex in Plasmodium liver infection
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