Role of plasmepsin V and PTEX complex in Plasmodium liver infection
Role of plasmepsin V and PTEX complex in Plasmodium liver infection
批准号:
nhmrc : GNT1139153
负责人:
A/Pr Justin Boddey
金额:
$84.84万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
Plasmepsin V and PTEX are essential proteins for malaria parasites to grow inside red blood cells. These proteins control the export of parasite proteins into red cells, causing disease. Before red blood cells are infected, parasites invade liver cells. Plasmepsin V and PTEX are expressed during liver infection but their function is currently unknown. We hypothesise that they allow parasites to export proteins into liver cells in order to survive and, thus, are antimalarial drug targets.
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The role of protein glycosylation in the malaria parasite
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批准号:nhmrc : 1139546
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项目类别:Project Grants
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资助金额:$43.57万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
The role of protein glycosylation in the malaria parasite
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批准号:nhmrc : GNT1139546
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项目类别:Project Grants
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资助金额:$64.44万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
Role of plasmepsin V and PTEX complex in Plasmodium liver infection
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批准号:nhmrc : 1139153
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项目类别:Project Grants
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资助金额:$57.36万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
Optimisation of a potent and fast acting antimalarial class that is orally efficacious in vivo
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批准号:nhmrc : GNT1135421
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项目类别:Development Grants
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资助金额:$68.39万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
Optimisation of a potent and fast acting antimalarial class that is orally efficacious in vivo
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批准号:nhmrc : 1135421
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项目类别:Development Grants
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资助金额:$46.24万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
Functional genomics of malaria liver infection and transmission
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批准号:nhmrc : 1123727
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项目类别:Career Development Fellowships
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资助金额:$32.12万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Functional genomics of malaria liver infection and transmission
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批准号:nhmrc : GNT1123727
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项目类别:Career Development Fellowships
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资助金额:$47.01万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Effector export in P. falciparum infected human erythrocytes
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批准号:nhmrc : 1121178
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项目类别:Project Grants
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资助金额:$72.85万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Effector export in P. falciparum infected human erythrocytes
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批准号:nhmrc : GNT1121178
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项目类别:Project Grants
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资助金额:$106.69万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Role of exported proteins in malaria parasite development in the liver
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批准号:nhmrc : 1049811
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项目类别:Project Grants
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资助金额:$34.71万
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财政年份:2013
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负责人:A/Pr Justin Boddey
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依托单位:
Function and inhibition of Plasmepsin V in targeting malaria virulence proteins into human erythrocytes
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批准号:nhmrc : 1010326
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项目类别:Project Grants
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资助金额:$27.2万
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财政年份:2011
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负责人:A/Pr Justin Boddey
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依托单位:
Identification of the Plasmodium falciparum translocon that exports parasite proteins into their erythocytic hosts.
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批准号:nhmrc : 516740
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项目类别:NHMRC Project Grants
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资助金额:$27.27万
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财政年份:2008
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负责人:A/Pr Justin Boddey
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依托单位:
characterisation of P. Flaciparum erythrocyte-targeted proteins
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批准号:nhmrc : 461281
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项目类别:Early Career Fellowships
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资助金额:$18.8万
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财政年份:2007
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负责人:A/Pr Justin Boddey
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依托单位:
海外基金