Optimisation of a potent and fast acting antimalarial class that is orally efficacious in vivo
Optimisation of a potent and fast acting antimalarial class that is orally efficacious in vivo
批准号:
nhmrc : GNT1135421
负责人:
A/Pr Justin Boddey
金额:
$68.39万
依托单位国家:
澳大利亚
项目类别:
Development Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 --
中文摘要
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英文摘要
Malaria is a devastating disease that results in 600 000 deaths annually. Current therapeutics used to combat malaria have a limited duration of use in the clinic due to the onset of resistance. We have identified a highly active antimalarial series that we propose to further develop to meet the prerequisites required for partnership with the Medicines for Malaria Venture (MMV) for progression into the clinic.
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会议论文
Role of plasmepsin V and PTEX complex in Plasmodium liver infection
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批准号:nhmrc : GNT1139153
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项目类别:Project Grants
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资助金额:$84.84万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
The role of protein glycosylation in the malaria parasite
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批准号:nhmrc : 1139546
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项目类别:Project Grants
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资助金额:$43.57万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
The role of protein glycosylation in the malaria parasite
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批准号:nhmrc : GNT1139546
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项目类别:Project Grants
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资助金额:$64.44万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
Role of plasmepsin V and PTEX complex in Plasmodium liver infection
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批准号:nhmrc : 1139153
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项目类别:Project Grants
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资助金额:$57.36万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
Optimisation of a potent and fast acting antimalarial class that is orally efficacious in vivo
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批准号:nhmrc : 1135421
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项目类别:Development Grants
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资助金额:$46.24万
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财政年份:2018
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负责人:A/Pr Justin Boddey
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依托单位:
Functional genomics of malaria liver infection and transmission
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批准号:nhmrc : 1123727
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项目类别:Career Development Fellowships
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资助金额:$32.12万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Functional genomics of malaria liver infection and transmission
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批准号:nhmrc : GNT1123727
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项目类别:Career Development Fellowships
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资助金额:$47.01万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Effector export in P. falciparum infected human erythrocytes
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批准号:nhmrc : 1121178
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项目类别:Project Grants
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资助金额:$72.85万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Effector export in P. falciparum infected human erythrocytes
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批准号:nhmrc : GNT1121178
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项目类别:Project Grants
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资助金额:$106.69万
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财政年份:2017
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负责人:A/Pr Justin Boddey
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依托单位:
Role of exported proteins in malaria parasite development in the liver
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批准号:nhmrc : 1049811
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项目类别:Project Grants
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资助金额:$34.71万
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财政年份:2013
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负责人:A/Pr Justin Boddey
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依托单位:
Function and inhibition of Plasmepsin V in targeting malaria virulence proteins into human erythrocytes
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批准号:nhmrc : 1010326
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项目类别:Project Grants
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资助金额:$27.2万
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财政年份:2011
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负责人:A/Pr Justin Boddey
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依托单位:
Identification of the Plasmodium falciparum translocon that exports parasite proteins into their erythocytic hosts.
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批准号:nhmrc : 516740
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项目类别:NHMRC Project Grants
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资助金额:$27.27万
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财政年份:2008
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负责人:A/Pr Justin Boddey
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依托单位:
characterisation of P. Flaciparum erythrocyte-targeted proteins
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批准号:nhmrc : 461281
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项目类别:Early Career Fellowships
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资助金额:$18.8万
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财政年份:2007
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负责人:A/Pr Justin Boddey
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依托单位:
海外基金