CHARACTERIZATION OF BLOOD FLOW IN DENTAL PULP

牙髓中血流的表征

• 批准号: 8169517
• 负责人: PETRA E WILDER-SMITH
• 金额: $ 0.21万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169517
• 关键词: Blood flow; Computer Retrieval of Information on Scientific Projects Database; Data; Dental; Dental Pulp; Diagnosis; Funding; Grant; Health; Image; In Vitro; Institution; Lasers; Measurement; Monitor; Periodontal Diseases; Research; Research Personnel; Resources; Source; Techniques; Tooth structure; United States National Institutes of Health; in vivo; instrument; prototype; pulpal blood flow; treatment planning; treatment response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Periodontal disease: Characterization of dental pulp, with Petra Wilder-Smith, UC-Irvine The ability to monitor pulpal vitality is crucial for accurate diagnosis and optimal treatment planning. Currently, there exists no accurate means of clinically assessing pulpal health and treatment response. The aim of this study is to develop and validate a non-invasive technique for non-invasively determining pulpal blood flow. In vitro studies have shown that laser speckle imaging using a 633 nm HeNe laser can detect blood flow values within the pulpal chambers of teeth. The ability to detect and semi-quantify different flow rates in the dental pulp has been clearly demonstrated. The data show that with higher flow rates, high speckle flow values are given. We currently are performing in vivo measurements with a prototype dental LSI instrument

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 牙周病：牙髓的表征，与加州大学欧文分校 Petra Wilder-Smith 合作 监测牙髓活力的能力对于准确诊断和最佳治疗计划至关重要。目前，尚无准确的临床评估牙髓健康和治疗反应的方法。本研究的目的是开发和验证一种用于非侵入性确定牙髓血流量的非侵入性技术。体外研究表明，使用 633 nm HeNe 激光进行激光散斑成像可以检测牙齿牙髓腔内的血流值。检测和半量化牙髓中不同流速的能力已得到明确证明。数据显示，流速越高，散斑流值就越高。我们目前正在使用原型牙科 LSI 仪器进行体内测量