Molecular Biophysics Training Grant

描述（由申请人提供）：本申请为西北大学分子生物物理学博士预科培养项目申请支持。过去来自培训补助金的支持在促进温伯格艺术与科学学院、麦考密克工程学院和范伯格医学院五个参与部门的教师、学生和博士后之间的跨学科互动方面发挥了重要作用。在生物、化学和工程院系聘用了许多对分子生物物理学有研究兴趣的教员，创造了一个高度互动的研究环境，重点是应用定量物理方法和方法来解决大分子结构和功能问题。生物物理培训计划受益于最先进的设备设施，包括凯克生物物理设施内的仪器，先进光子源大分子晶体学的两条光束线和其他关键研究资源。

DESCRIPTION (provided by applicant): This proposal is a request for support of the Northwestern University pre-doctoral training program in Molecular Biophysics. Past support from the training grant has played a major role in stimulating interdisciplinary interactions between faculty, students and post-doctoral fellows within five participating departments in the Weinberg College of Arts and Sciences, the McCormick School of Engineering and the Feinberg School of Medicine. The hiring of many faculty in biology, chemistry and engineering departments with research interests in molecular biophysics has generated a highly-interactive research environment focused on the application of quantitative physical methods and approaches to problems of macromolecular structure and function. The Biophysics Training Program benefits from access to state-of-the-art equipment facilities, including instrumentation within the Keck Biophysics Facility, two beamlines for macromolecular crystallography at the Advanced Photon Source and other key research resources. The training program has a core biophysics curriculum to be followed by students entering through each of the participating graduate programs, providing a common didactic experience to students with diverse educational backgrounds. Advanced graduate-level courses in key research areas of the program, such as structural biology are central to the training experience. Students also participate in monthly Biophysics Club and Journal Club meetings, and attend a Biophysics Seminar Series as part of the program. Support for biophysics students is requested for the 2nd-4th years of graduate education, enhancing the Training Program role in mentoring students through key stages of their graduate studies. The training of graduate students in Biophysics provides them a quantitative foundation for studying biological processes relevant to a wide range of public health issues. Biophysical methods are centrally important in modern drug discovery and design, and graduate students trained in these methods are well positioned to further our understanding and intervention in a wide range of human diseases.